(Q34488383)

2 August 2017

Crucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation (English)

1 reference

2 August 2017

0 references

Florian Stengel

6

0 references

Janine Kirstein

Janine Kirstein

2

0 references

Matthias P. Mayer

Matthias P Mayer

14

0 references

Rebecca C Wade

Rebecca C Wade

12

0 references

Bernd Bukau

15

Bernd Bukau

1 reference

2 August 2017

10

Ruedi Aebersold

1 reference

2 August 2017

Nadinath B Nillegoda

1

0 references

Xuechao Gao

8

Xuechao Gao

1 reference

2 August 2017

11

D Lys Guilbride

1 reference

2 August 2017

4

Mykhaylo Berynskyy

1 reference

2 August 2017

7

Kristin Arnsburg

1 reference

2 August 2017

9

Annika Scior

1 reference

2 August 2017

3

Anna Szlachcic

1 reference

2 August 2017

Antonia Stank

5

1 reference

PubMed ID

26245380

2 August 2017

Richard I Morimoto

13

1 reference

PubMed ID

26245380

2 August 2017

language of work or name

English

0 references

publication date

5 August 2015

1 reference

2 August 2017

1 reference

2 August 2017

524

1 reference

2 August 2017

7564

1 reference

2 August 2017

247-251

1 reference

https://scigraph.springernature.com/pub.10.1038/nature14884

2 August 2017

0 references

cites work

SDA 7: A modular and parallel implementation of the simulation of diffusional association software

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Specification of Hsp70 function by Type I and Type II Hsp40.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Proteostasis impairment in protein-misfolding and -aggregation diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Regulated structural transitions unleash the chaperone activity of αB-crystallin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

The nascent polypeptide-associated complex is a key regulator of proteostasis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Metazoan Hsp70 machines use Hsp110 to power protein disaggregation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Expanding the chemical cross-linking toolbox by the use of multiple proteases and enrichment by size exclusion chromatography

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Dynamics of the T4 bacteriophage DNA packasome motor: endonuclease VII resolvase release of arrested Y-DNA substrates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Peptide-binding sites as revealed by the crystal structures of the human Hsp40 Hdj1 C-terminal domain in complex with the octapeptide from human Hsp70

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: a historical perspective.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

The SWISS-MODEL Repository and associated resources

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Functional divergence between co-chaperones of Hsc70.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Identification of cross-linked peptides from large sequence databases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Network of general and specialty J protein chaperones of the yeast cytosol

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Molecular chaperones of the Hsp110 family act as nucleotide exchange factors of Hsp70s

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Chaperone network in the yeast cytosol: Hsp110 is revealed as an Hsp70 nucleotide exchange factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Hsp70 chaperones accelerate protein translocation and the unfolding of stable protein aggregates by entropic pulling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Hsp70 chaperones: cellular functions and molecular mechanism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Low resolution structural study of two human HSP40 chaperones in solution. DJA1 from subfamily A and DJB4 from subfamily B have different quaternary structures

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Thermotolerance requires refolding of aggregated proteins by substrate translocation through the central pore of ClpB.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

The SWISS-MODEL Repository of annotated three-dimensional protein structure homology models

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

The crystal structure of the yeast Hsp40 Ydj1 complexed with its peptide substrate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Scanning mutagenesis identifies amino acid residues essential for the in vivo activity of the Escherichia coli DnaJ (Hsp40) J-domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Folding of malate dehydrogenase inside the GroEL-GroES cavity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Sequential mechanism of solubilization and refolding of stable protein aggregates by a bichaperone network

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Structural features required for the interaction of the Hsp70 molecular chaperone DnaK with its cochaperone DnaJ.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Computer simulation of protein-protein association kinetics: acetylcholinesterase-fasciculin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Protein folding activity of Hsp70 is modified differentially by the hsp40 co-chaperones Sis1 and Ydj1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Role of the J-domain in the cooperation of Hsp40 with Hsp70.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Structure, function and evolution of DnaJ: conservation and adaptation of chaperone function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Simulation of the diffusional association of barnase and barstar.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Nuclear magnetic resonance solution structure of the human Hsp40 (HDJ-1) J-domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

A conserved HPD sequence of the J-domain is necessary for YDJ1 stimulation of Hsp70 ATPase activity at a site distinct from substrate binding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Protein disaggregation mediated by heat-shock protein Hsp104.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

WHAT IF: a molecular modeling and drug design program

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4830470

Conserved central domains control the quaternary structure of type I and type II Hsp40 molecular chaperones.

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14884

Hsp110 is a nucleotide-activated exchange factor for Hsp70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14884

A chaperone pathway in protein disaggregation. Hsp26 alters the nature of protein aggregates to facilitate reactivation by Hsp104.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14884

Disassembling protein aggregates in the yeast cytosol. The cooperation of Hsp26 with Ssa1 and Hsp104.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14884

Structural and functional specificity of small heat shock protein HspB1 and HspB4, two cellular partners of HspB5: role of the in vitro hetero-complex formation in chaperone activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14884

False discovery rate estimation for cross-linked peptides identified by mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14884

New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14884

The roles of the two zinc binding sites in DnaJ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14884

Hsc70 contacts helix III of the J domain from polyomavirus T antigens: addressing a dilemma in the chaperone hypothesis of how they release E2F from pRb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14884

Electrostatics and diffusion of molecules in solution: simulations with the University of Houston Brownian Dynamics program

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14884

On the Contributions of Diffusion and Thermal Activation to Electron Transfer betweenPhormidium laminosumPlastocyanin and Cytochromef: Brownian Dynamics Simulations with Explicit Modeling of Nonpolar Desolvation Interactions and Electron Transfer Eve

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14884

Improved photostable FRET-competent biarsenical-tetracysteine probes based on fluorinated fluoresceins

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26245380

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The conserved carboxyl terminus and zinc finger-like domain of the co-chaperone Ydj1 assist Hsp70 in protein folding

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26245380

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Development and Testing of the OPLS All-Atom Force Field on Conformational Energetics and Properties of Organic Liquids

1 reference

https://api.crossref.org/works/10.1038%2FNATURE14884

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE14884

1 reference

journals/nature/NillegodaKSBSSA15

2 August 2017

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

2 August 2017

1 reference

PubMed ID

26245380