(Q34491446)

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CK2-mediated hyperphosphorylation of topoisomerase I targets serine 506, enhances topoisomerase I-DNA binding, and increases cellular camptothecin sensitivity

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

CK2-mediated hyperphosphorylation of topoisomerase I targets serine 506, enhances topoisomerase I-DNA binding, and increases cellular camptothecin sensitivity (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

author name string

Keya Bandyopadhyay

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Pingchuan Li

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Ruth A Gjerset

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

language of work or name

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publication date

21 November 2012

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

e50427

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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Creative Commons Attribution 4.0 International

21 November 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Overexpression of nuclear protein kinase CK2 α catalytic subunit (CK2α) as a poor prognosticator in human colorectal cancer

1 reference

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6 July 2018

Protein kinase CK2 is a central regulator of topoisomerase I hyperphosphorylation and camptothecin sensitivity in cancer cell lines

1 reference

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6 July 2018

Inhibition of topoisomerase I prevents chromosome breakage at common fragile sites

1 reference

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6 July 2018

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

1 reference

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6 July 2018

Protein kinase CK2 in health and disease: CK2: a key player in cancer biology

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6 July 2018

Mitotic phosphorylation stimulates DNA relaxation activity of human topoisomerase I

1 reference

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6 July 2018

Serine phosphorylation-dependent coregulation of topoisomerase I by the p14ARF tumor suppressor

1 reference

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6 July 2018

DNA damage disrupts the p14ARF-B23(nucleophosmin) interaction and triggers a transient subnuclear redistribution of p14ARF.

1 reference

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p53 stimulates human topoisomerase I activity by modulating its DNA binding.

1 reference

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6 July 2018

Delineation of the domains required for physical and functional interaction of p14ARF with human topoisomerase I.

1 reference

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6 July 2018

The development of camptothecin analogs in childhood cancers

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A human topoisomerase I cleavage complex is recognized by an additional human topisomerase I molecule in vitro.

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DNA topoisomerases: structure, function, and mechanism

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6 July 2018

Human ARF protein interacts with topoisomerase I and stimulates its activity

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Megabase chromatin domains involved in DNA double-strand breaks in vivo

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Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA

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DNA topoisomerases

1 reference

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Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

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Topoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiae

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Phosphorylation of topoisomerase I in L5178Y-S cells is associated with poly(ADP-ribose) metabolism.

1 reference

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Association of elevated protein kinase CK2 activity with aggressive behavior of squamous cell carcinoma of the head and neck.

1 reference

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Functionally distinct human marrow stromal cell lines immortalized by transduction with the human papilloma virus E6/E7 genes.

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Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung

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DNA topoisomerase poisons as antitumor drugs

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Vaccinia DNA topoisomerase I promotes illegitimate recombination in Escherichia coli

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Phosphorylation sites for type N II protein kinase in DNA-topoisomerase I from calf thymus

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Cleavage of DNA by mammalian DNA topoisomerase II

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Interactions between eukaryotic DNA topoisomerase I and a specific binding sequence.

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DNA strand transfer reactions catalyzed by vaccinia topoisomerase I

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Nuclear casein kinase 2 (CK-2) activity in human normal, benign hyperplastic, and cancerous prostate

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1 reference

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Identifiers

10.1371/JOURNAL.PONE.0050427

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

2012PLoSO...750427B

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

ResearchGate publication ID

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