(Q34498165)

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Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture

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scholarly article

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Europe PubMed Central

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2 August 2017

Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture (English)

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Europe PubMed Central

PubMed publication ID

2 August 2017

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Werner syndrome

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Hiroyuki Seimiya

object named as

Hiroyuki Seimiya

14

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author name string

Akira Shimamoto

1

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Europe PubMed Central

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2 August 2017

Harunobu Kagawa

2

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2 August 2017

Kazumasa Zensho

3

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2 August 2017

Yukihiro Sera

4

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2 August 2017

Yasuhiro Kazuki

5

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2 August 2017

Mitsuhiko Osaki

6

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2 August 2017

Mitsuo Oshimura

7

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2 August 2017

Yasuhito Ishigaki

8

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2 August 2017

Kanya Hamasaki

9

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2 August 2017

Yoshiaki Kodama

10

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2 August 2017

Shinsuke Yuasa

11

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2 August 2017

Keiichi Fukuda

12

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2 August 2017

Kyotaro Hirashima

13

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2 August 2017

Hirofumi Koyama

15

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2 August 2017

Takahiko Shimizu

16

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2 August 2017

Minoru Takemoto

17

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Europe PubMed Central

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2 August 2017

Koutaro Yokote

18

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Europe PubMed Central

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2 August 2017

Makoto Goto

19

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2 August 2017

Hidetoshi Tahara

20

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2 August 2017

language of work or name

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publication date

12 November 2014

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2 August 2017

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Europe PubMed Central

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2 August 2017

9

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Europe PubMed Central

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2 August 2017

11

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Europe PubMed Central

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2 August 2017

e112900

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Europe PubMed Central

PubMed publication ID

2 August 2017

copyright license

Creative Commons Attribution 4.0 International

12 November 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

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describes a project that uses

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TIG-3 iPSC #10-2

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Telomerase protects Werner syndrome lineage-specific stem cells from premature aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Cellular senescence and its effector programs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Werner syndrome: a changing pattern of clinical manifestations in Japan (1917~2008).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

The STAT3-IGFBP5 axis is critical for IL-6/gp130-induced premature senescence in human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Induced pluripotent stem cells: opportunities and challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

DNA damage-mediated induction of a chemoresistant niche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Induced pluripotency: history, mechanisms, and applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Robust activation of the human but not mouse telomerase gene during the induction of pluripotency.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Spontaneous reversal of the developmental aging of normal human cells following transcriptional reprogramming

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Inflammaging (inflammation + aging): A driving force for human aging based on an evolutionarily antagonistic pleiotropy theory?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Roles of Werner syndrome protein in protection of genome integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Angiopoietin-like protein 2 promotes chronic adipose tissue inflammation and obesity-related systemic insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Generation of pluripotent stem cells from adult mouse liver and stomach cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Induced pluripotent stem cell lines derived from human somatic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Telomere dysfunction as a cause of genomic instability in Werner syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Werner Syndrome as an example of inflamm-aging: possible therapeutic opportunities for a progeroid syndrome?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Molecular biology of Werner syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Werner's syndrome: from clinics to genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Plat-E: an efficient and stable system for transient packaging of retroviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Excess of rare cancers in Werner syndrome (adult progeria)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Positional cloning of the Werner's syndrome gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4229309

7 July 2018

Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0112900

21 January 2018

Karotypic abnormalities in human induced pluripotent stem cells and embryonic stem cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0112900

21 January 2018

Dysadipocytokinemia in werner syndrome and its recovery by treatment with pioglitazone

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0112900

21 January 2018

Telomerase expression prevents replicative senescence but does not fully reset mRNA expression patterns in Werner syndrome cell strains

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0112900

21 January 2018

Analysis of helicase gene mutations in Japanese Werner's syndrome patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25390333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation and haplotype analyses of the Werner's syndrome gene based on its genomic structure: genetic epidemiology in the Japanese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/25390333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recurrent copy number variations in human induced pluripotent stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25390333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homozygous and compound heterozygous mutations at the Werner syndrome locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/25390333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/25390333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging-associated inflammation in healthy Japanese individuals and patients with Werner syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/25390333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of radical-scavenging enzymes and reduced oxygen exposure on growth and chromosome abnormalities of Werner syndrome cultured skin fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/25390333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of clonal attenuation, clonal succession, and clonal expansion in mass cultures of aging Werner's syndrome skin fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/25390333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of osteoporosis in a patient with Werner's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/25390333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aneuploidy in somatic cells of in utero exposed A-bomb survivors in Hiroshima

1 reference

https://pubmed.ncbi.nlm.nih.gov/25390333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of interleukin-1 alpha and beta in early passage fibroblasts from aging individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/25390333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased blood plasminogen activator inhibitor-1 and intercellular adhesion molecule-1 as possible risk factors of atherosclerosis in Werner syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/25390333

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0112900

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

2014PLoSO...9k2900S

0 references

release_6xs5ti4jyfffnmey6wxgkeljvq

1 reference

https://api.fatcat.wiki/v0/release/6xs5ti4jyfffnmey6wxgkeljvq

24 November 2022

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mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

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2 August 2017

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