(Q34504952)

2 August 2017

Cerebrospinal fluid IL-12p40, CXCL13 and IL-8 as a combinatorial biomarker of active intrathecal inflammation (English)

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2 August 2017

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Bibiana Bielekova

1

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2 August 2017

Mika Komori

2

1 reference

2 August 2017

Quangang Xu

3

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2 August 2017

Daniel S Reich

4

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2 August 2017

Tianxia Wu

5

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2 August 2017

language of work or name

English

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publication date

30 November 2012

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2 August 2017

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2 August 2017

7

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2 August 2017

11

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2 August 2017

e48370

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Creative Commons CC0 License

2 August 2017

start time

30 November 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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cites work

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Intrathecal effects of daclizumab treatment of multiple sclerosis

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Francisella tularensis LVS-induced Interleukin-12 p40 cytokine production mediates dendritic cell migration through IL-12 Receptor β1.

7 July 2018

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7 July 2018

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Diagnostic accuracy and receiver-operating characteristics curve analysis in surgical research and decision making

7 July 2018

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Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course.

7 July 2018

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Analysis of biomarker data: logs, odds ratios, and receiver operating characteristic curves

7 July 2018

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The chemokine CXCL13 is a prognostic marker in clinically isolated syndrome (CIS).

7 July 2018

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IL-8 in cerebrospinal fluid from children with acute encephalopathy is higher than in that from children with febrile seizure

7 July 2018

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CXCL13 as a cerebrospinal fluid marker for neurosyphilis in HIV-infected patients with syphilis

7 July 2018

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The chemokine CXCL13 is a key regulator of B cell recruitment to the cerebrospinal fluid in acute Lyme neuroborreliosis.

7 July 2018

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Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation

7 July 2018

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The relation between inflammation and neurodegeneration in multiple sclerosis brains.

7 July 2018

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IL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12R beta 1.

7 July 2018

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Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study

7 July 2018

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IL-12p40: an inherently agonistic cytokine

7 July 2018

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Rituximab reduces B cells and T cells in cerebrospinal fluid of multiple sclerosis patients

7 July 2018

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The chemokine CXCL13 is a key molecule in autoimmune myasthenia gravis

7 July 2018

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Monocyte-like and mature macrophages produce CXCL13 (B cell-attracting chemokine 1) in inflammatory lesions with lymphoid neogenesis

7 July 2018

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IL-12 p40 homodimer-dependent macrophage chemotaxis and respiratory viral inflammation are mediated through IL-12 receptor beta 1.

7 July 2018

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The power of combinatorial immunology: IL-12 and IL-12-related dimeric cytokines in infectious diseases

7 July 2018

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Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node development

7 July 2018

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IL-12: the role of p40 versus p75

7 July 2018

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7 July 2018

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Reduced T helper 1 responses in IL-12 p40 transgenic mice.

7 July 2018

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Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine.

7 July 2018

1 reference

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Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity

7 July 2018

1 reference

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Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions

7 July 2018

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Production of hemolymphopoietic cytokines (IL-6, IL-8, colony-stimulating factors) by normal human astrocytes in response to IL-1 beta and tumor necrosis factor-alpha

7 July 2018

1 reference

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Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology.

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048370

Meningeal T cells associate with diffuse axonal loss in multiple sclerosis spinal cords.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048370

Cerebrospinal fluid abnormalities in a phase III trial of Avonex (IFNbeta-1a) for relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048370

Differences in the inducible gene expression and protein production of IL-12p40, IL-12p70 and IL-23: involvement of p38 and JNK kinase pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048370

The ratio of P40 monomer to dimer is an important determinant of IL-12 bioactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048370

Increased cerebrospinal fluid concentrations of the chemokine CXCL13 in active MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048370

Chemokines in multiple sclerosis: CXCL12 and CXCL13 up-regulation is differentially linked to CNS immune cell recruitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048370

Key role of CXCL13/CXCR5 axis for cerebrospinal fluid B cell recruitment in pediatric OMS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048370

BLC (CXCL13) is expressed by different dendritic cell subsets in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048370

Expression of B-cell-attracting chemokine 1 (CXCL13) by malignant lymphocytes and vascular endothelium in primary central nervous system lymphoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048370

Intracerebral expression of CXCL13 and BAFF is accompanied by formation of lymphoid follicle-like structures in the meninges of mice with relapsing experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048370

Approach to discriminate subgroups in multiple sclerosis with cerebrospinal fluid (CSF) basic inflammation indices and TNF-alpha, IL-1beta, IL-6, IL-8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048370

Detection of MCP-1 and IL-8 in the serum and cerebrospinal fluid of a child with Miller Fisher syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0048370

Herpes simplex virus type 1-mediated up-regulation of IL-12 (p40) mRNA expression. Implications in immunopathogenesis and protection.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3511462

Lymphoid chemokine B cell-attracting chemokine-1 (CXCL13) is expressed in germinal center of ectopic lymphoid follicles within the synovium of chronic arthritis patients

27 October 2018

1 reference

12 December 2020

Ectopic expression of the B cell-attracting chemokine BCA-1 (CXCL13) on endothelial cells and within lymphoid follicles contributes to the establishment of germinal center-like structures in Sjögren's syndrome

1 reference

12 December 2020

Expression of the B cell-attracting chemokine CXCL13 in the target organ and autoantibody production in ectopic lymphoid tissue in the chronic inflammatory disease Sjögren's syndrome

1 reference

12 December 2020

IL-8 is a key mediator of neuroinflammation in severe traumatic brain injuries

1 reference

12 December 2020

The IL-12 p40 homodimer as a specific antagonist of the IL-12 heterodimer

1 reference

12 December 2020

IL-12 p40 messenger RNA expression in target organs during acute graft-versus-host disease. Possible involvement of IFN-gamma

1 reference

12 December 2020

Differential effects of IL-12 receptor blockade with IL-12 p40 homodimer on the induction of CD4+ and CD8+ IFN-gamma-producing cells

1 reference

12 December 2020

Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis

1 reference

12 December 2020

Systematic microanatomical analysis of CXCL13 and CCL21in situ production and progressive lymphoid organization in rheumatoid synovitis

1 reference

12 December 2020

B-Cells in ocular adnexal lymphoproliferative lesions express B-cell attracting chemokine 1 (CXCL13)

1 reference

12 December 2020

The secreted form of the p40 subunit of interleukin (IL)-12 inhibits IL-23 functions and abrogates IL-23-mediated antitumour effects

1 reference

12 December 2020

Characterization of CXCL13+ neoplastic t cells in cutaneous lesions of angioimmunoblastic T-cell lymphoma (AITL)

1 reference

12 December 2020

CXCL13 and CCL21 are expressed in ectopic lymphoid follicles in cutaneous lymphoproliferative disorders

1 reference

12 December 2020

Diagnostic reliability of cerebral spinal fluid tests for acute confusional state (delirium) in patients with systemic lupus erythematosus: interleukin 6 (IL-6), IL-8, interferon-alpha, IgG index, and Q-albumin

1 reference

12 December 2020

IL-6 and IL-8 in cerebrospinal fluid from patients with aseptic meningitis and bacterial meningitis: their potential role as a marker for differential diagnosis

1 reference

12 December 2020

Multiple sclerosis: BAFF and CXCL13 in cerebrospinal fluid

1 reference

12 December 2020

Cerebrospinal fluid levels of CXCL13 are elevated in neuromyelitis optica

1 reference

12 December 2020

Induction of lymphotoxin-alpha by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70

1 reference

12 December 2020

Natalizumab treatment in multiple sclerosis: marked decline of chemokines and cytokines in cerebrospinal fluid

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0048370

Identifiers

DOI

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2 August 2017

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2 August 2017

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