(Q34506519)

2 August 2017

title

ATP binding to p97/VCP D1 domain regulates selective recruitment of adaptors to its proximal N-domain (English)

1 reference

2 August 2017

Feng Rao

3

0 references

author name string

Wei Sheng Chia

1

1 reference

2 August 2017

Diana Xueqi Chia

2

1 reference

2 August 2017

Shoshana Bar Nun

4

1 reference

2 August 2017

Susana Geifman Shochat

5

1 reference

2 August 2017

language of work or name

English

0 references

publication date

3 December 2012

1 reference

2 August 2017

1 reference

2 August 2017

volume

7

1 reference

2 August 2017

issue

12

1 reference

2 August 2017

page(s)

e50490

1 reference

Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

3 December 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD model

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A novel ATP-dependent conformation in p97 N–D1 fragment revealed by crystal structures of disease-related mutants

7 July 2018

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7 July 2018

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ATP-bound form of the D1 AAA domain inhibits an essential function of Cdc48p/p97.

7 July 2018

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7 July 2018

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Analysis of Npl4 deletion mutants in mammalian cells unravels new Ufd1-interacting motifs and suggests a regulatory role of Npl4 in ERAD.

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7 July 2018

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Insights into adaptor binding to the AAA protein p97.

7 July 2018

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The use of differential scanning fluorimetry to detect ligand interactions that promote protein stability

7 July 2018

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7 July 2018

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7 July 2018

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Central pore residues mediate the p97/VCP activity required for ERAD

7 July 2018

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Conformational changes in the AAA ATPase p97-p47 adaptor complex

7 July 2018

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7 July 2018

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7 July 2018

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Nucleotide dependent motion and mechanism of action of p97/VCP

7 July 2018

1 reference

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p97 and close encounters of every kind: a brief review

7 July 2018

1 reference

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Physical and functional interaction between Dorfin and Valosin-containing protein that are colocalized in ubiquitylated inclusions in neurodegenerative disorders

7 July 2018

1 reference

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Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein

7 July 2018

1 reference

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Structural basis of the interaction between the AAA ATPase p97/VCP and its adaptor protein p47

7 July 2018

1 reference

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Molecular clearance of ataxin-3 is regulated by a mammalian E4

7 July 2018

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The crystal structure of murine p97/VCP at 3.6A

7 July 2018

1 reference

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Distinct roles for the AAA ATPases NSF and p97 in the secretory pathway

7 July 2018

1 reference

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Distinct steps in dislocation of luminal endoplasmic reticulum-associated degradation substrates: roles of endoplamic reticulum-bound p97/Cdc48p and proteasome

7 July 2018

1 reference

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Complete structure of p97/valosin-containing protein reveals communication between nucleotide domains

7 July 2018

1 reference

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What determines the intracellular ATP concentration

7 July 2018

1 reference

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Motions and negative cooperativity between p97 domains revealed by cryo-electron microscopy and quantised elastic deformational model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

Hexamerization of p97-VCP is promoted by ATP binding to the D1 domain and required for ATPase and biological activities

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

ATPase activity of p97-valosin-containing protein (VCP). D2 mediates the major enzyme activity, and D1 contributes to the heat-induced activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

Cdc48 can distinguish between native and non-native proteins in the absence of cofactors.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

Cdc48-Ufd1-Npl4: stuck in the middle with Ub.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

Structure of the AAA ATPase p97

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

AAA proteins. Lords of the ring

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

The p47 co-factor regulates the ATPase activity of the membrane fusion protein, p97

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

Involvement of valosin-containing protein, an ATPase Co-purified with IkappaBalpha and 26 S proteasome, in ubiquitin-proteasome-mediated degradation of IkappaBalpha

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

p47 is a cofactor for p97-mediated membrane fusion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

Cdc48p interacts with Ufd3p, a WD repeat protein required for ubiquitin-mediated proteolysis in Saccharomyces cerevisiae.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3513293

Conformational changes of p97 during nucleotide hydrolysis determined by small-angle X-Ray scattering

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050490

Cdc48 (p97): a "molecular gearbox" in the ubiquitin pathway?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050490

VCP/p97 in abnormal protein aggregates, cytoplasmic vacuoles, and cell death, phenotypes relevant to neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050490

Involvement of valosin-containing protein (VCP)/p97 in the formation and clearance of abnormal protein aggregates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050490

Vacuole-creating protein in neurodegenerative diseases in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050490

The AAA ATPase p97/VCP interacts with its alternative co-factors, Ufd1-Npl4 and p47, through a common bipartite binding mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050490

Werner syndrome protein directly binds to the AAA ATPase p97/VCP in an ATP-dependent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050490

Ubiquitous soluble Mg2+-ATPase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0050490

A Major Conformational Change in p97 AAA ATPase upon ATP Binding

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23226521

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Going through the motions: The ATPase cycle of p97

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23226521

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0050490

1 reference

release_hw5oxwskq5fylkykpjvvxoet2u

2 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hw5oxwskq5fylkykpjvvxoet2u

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

3513293

1 reference

2 August 2017

1 reference