(Q34509446)

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Neuroprotective drug riluzole amplifies the heat shock factor 1 (HSF1)- and glutamate transporter 1 (GLT1)-dependent cytoprotective mechanisms for neuronal survival

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098017%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Neuroprotective drug riluzole amplifies the heat shock factor 1 (HSF1)- and glutamate transporter 1 (GLT1)-dependent cytoprotective mechanisms for neuronal survival (English)

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098017%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1

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16 January 2020

Bonnie L Firestein

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098017%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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Rohan Mathur

2

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16 January 2020

Newton Mei

3

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16 January 2020

Christopher G Langhammer

4

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16 January 2020

Bruce Babiarz

5

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16 January 2020

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22 November 2010

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16 January 2020

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10

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Journal of Biological Chemistry

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16 January 2020

286

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16 January 2020

4

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16 January 2020

2785-2794

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Europe PubMed Central

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16 January 2020

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11 June 2022

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Chemical and biological approaches synergize to ameliorate protein-folding diseases.

1 reference

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7 July 2018

New candidate genes for heat resistance in Drosophila melanogaster are regulated by HSF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

7 July 2018

Riluzole increases the amount of latent HSF1 for an amplified heat shock response and cytoprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

7 July 2018

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1 reference

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7 July 2018

Changes in the regulation of heat shock gene expression in neuronal cell differentiation

1 reference

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7 July 2018

Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

7 July 2018

Genome-wide analysis of human HSF1 signaling reveals a transcriptional program linked to cellular adaptation and survival

1 reference

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7 July 2018

Genome-wide analysis reveals new roles for the activation domains of the Saccharomyces cerevisiae heat shock transcription factor (Hsf1) during the transient heat shock response

1 reference

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7 July 2018

Dynamic regulation and involvement of the heat shock transcriptional response in arsenic carcinogenesis

1 reference

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7 July 2018

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7 July 2018

Heat shock response modulators as therapeutic tools for diseases of protein conformation

1 reference

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7 July 2018

A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans

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7 July 2018

Glutamate inhibition in MS: the neuroprotective properties of riluzole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

7 July 2018

Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression.

1 reference

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7 July 2018

Modulation of neurodegeneration by molecular chaperones

1 reference

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7 July 2018

Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs

1 reference

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7 July 2018

Genome-wide analysis of the biology of stress responses through heat shock transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

7 July 2018

Riluzole enhances glutamate uptake in rat astrocyte cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

7 July 2018

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

1 reference

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7 July 2018

Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

7 July 2018

High threshold for induction of the stress response in motor neurons is associated with failure to activate HSF1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

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1 reference

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Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay

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7 July 2018

Expression of a variant form of the glutamate transporter GLT1 in neuronal cultures and in neurons and astrocytes in the rat brain

1 reference

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7 July 2018

Roles of the heat shock transcription factors in regulation of the heat shock response and beyond

1 reference

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7 July 2018

Evaluation of the neuroprotective effects of sodium channel blockers after spinal cord injury: improved behavioral and neuroanatomical recovery with riluzole.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

7 July 2018

Glutamate transporters in neurologic disease

1 reference

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7 July 2018

HSF1 is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

7 July 2018

Rapid and reversible relocalization of heat shock factor 1 within seconds to nuclear stress granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

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Targeted disruption of heat shock transcription factor 1 abolishes thermotolerance and protection against heat-inducible apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

7 July 2018

HSF1 granules: a novel stress-induced nuclear compartment of human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

7 July 2018

Differential action of riluzole on tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

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Riluzole. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3024774

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Cells in stress: transcriptional activation of heat shock genes

1 reference

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7 July 2018

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1 reference

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Transduction of the stress signal and mechanisms of transcriptional regulation of heat shock/stress protein gene expression in higher eukaryotes.

1 reference

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1 reference

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7 July 2018

Stress-induced oligomerization and chromosomal relocalization of heat-shock factor

1 reference

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Transcriptional regulation of heat shock genes. A paradigm for inducible genomic responses

1 reference

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7 July 2018

Neural differentiation and the attenuated heat shock response.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.158220

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Alpha-linolenic acid and riluzole treatment confer cerebral protection and improve survival after focal brain ischemia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.158220

21 January 2018

Neuroprotective effects of riluzole and ketamine during transient spinal cord ischemia in the rabbit.

1 reference

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Riluzole reduces brain swelling and contusion volume in rats following controlled cortical impact injury.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.158220

21 January 2018

Riluzole slows the progression of neuromuscular dysfunction in the wobbler mouse motor neuron disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.158220

21 January 2018

Stress, aging, and neurodegenerative disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21098017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astroglia-mediated effects of uric acid to protect spinal cord neurons from glutamate toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21098017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between heat shock transcription factors (HSFs) and divergent binding sequences: binding specificities of yeast HSFs and human HSF1

1 reference

https://pubmed.ncbi.nlm.nih.gov/21098017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of intracellular protein degradation in IMR-90 human diploid fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/21098017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/21098017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HSF1 transcription factor concentrates in nuclear foci during heat shock: relationship with transcription sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/21098017

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.158220

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098017%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098017%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21098017%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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