(Q34509716)

2 August 2017

title

Plasma membrane cholesterol as a regulator of human and rodent P2X7 receptor activation and sensitization (English)

1 reference

2 August 2017

Philip Smith

3

0 references

author name string

Lucy E Robinson

series ordinal

1

1 reference

2 August 2017

Mitesh Shridar

series ordinal

2

1 reference

2 August 2017

Ruth D Murrell-Lagnado

series ordinal

4

1 reference

2 August 2017

language of work or name

English

0 references

publication date

3 October 2014

1 reference

Journal of Biological Chemistry

2 August 2017

published in

1 reference

2 August 2017

volume

289

1 reference

2 August 2017

issue

46

1 reference

2 August 2017

page(s)

31983-31994

1 reference

describes a project that uses

2 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4231676/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

The trafficking and targeting of P2X receptors

1 reference

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Multiple roles of the extracellular vestibule amino acid residues in the function of the rat P2X4 receptor

7 July 2018

1 reference

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A dual polybasic motif determines phosphoinositide binding and regulation in the P2X channel family

7 July 2018

1 reference

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Innate immunosenescence: effect of aging on cells and receptors of the innate immune system in humans

7 July 2018

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Splice variants of the P2X7 receptor reveal differential agonist dependence and functional coupling with pannexin-1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Multiple cholesterol recognition/interaction amino acid consensus (CRAC) motifs in cytosolic C tail of Slo1 subunit determine cholesterol sensitivity of Ca2+- and voltage-gated K+ (BK) channels

7 July 2018

1 reference

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Fluvastatin suppresses native and recombinant human P2X4 receptor function

7 July 2018

1 reference

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7 July 2018

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The human P2X7 receptor and its role in innate immunity

7 July 2018

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Lipid rafts control P2X3 receptor distribution and function in trigeminal sensory neurons of a transgenic migraine mouse model

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Plasma membrane cholesterol plays a critical role in the Salmonella-induced anti-inflammatory response in intestinal epithelial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Intracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Identification of human P2X1 receptor-interacting proteins reveals a role of the cytoskeleton in receptor regulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Purinergic P2X7 receptor regulates lung surfactant secretion in a paracrine manner.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Functional characterization of putative cholesterol binding sequence (CRAC) in human type-1 cannabinoid receptor

7 July 2018

1 reference

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Probes for studying cholesterol binding and cell biology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Activation of P2X receptors induces apoptosis in human retinal pigment epithelium

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Lipid raft association and cholesterol sensitivity of P2X1-4 receptors for ATP: chimeras and point mutants identify intracellular amino-terminal residues involved in lipid regulation of P2X1 receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Interaction and interrelation of P2X7 and P2X4 receptor complexes in mouse lung epithelial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

C-terminal calmodulin-binding motif differentially controls human and rat P2X7 receptor current facilitation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Cholesterol and ion channels

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Lipid rafts as a membrane-organizing principle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Extracellular ATP dissociates nonmuscle myosin from P2X(7) complex: this dissociation regulates P2X(7) pore formation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Analysis of assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Sterols are mainly in the cytoplasmic leaflet of the plasma membrane and the endocytic recycling compartment in CHO cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

The P2X7 receptor channel pore dilates under physiological ion conditions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Signaling at purinergic P2X receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Facilitation of P2X7 receptor currents and membrane blebbing via constitutive and dynamic calmodulin binding.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Characterization of the molecular interaction between caveolin-1 and the P2X receptors 4 and 7 in E10 mouse lung alveolar epithelial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

P2X(7) receptor: Death or life?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Agonist potency at P2X7 receptors is modulated by structurally diverse lipids

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Caveolin-1 influences P2X7 receptor expression and localization in mouse lung alveolar epithelial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Regulation of ATP-gated P2X receptors by phosphoinositides

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Characterization and comparison of raft-like membranes isolated by two different methods from rat submandibular gland cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

P2X7 and phospholipid signalling: the search of the "missing link" in epithelial cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Coupling of two pools of P2X7 receptors to distinct intracellular signaling pathways in rat submandibular gland

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Involvement of de novo ceramide biosynthesis in macrophage death induced by activation of ATP-sensitive P2X7 receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

ATP-induced apoptosis of thymocytes is mediated by activation of P2 X 7 receptor and involves de novo ceramide synthesis and mitochondria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

N-methyl-D-glucamine and propidium dyes utilize different permeation pathways at rat P2X(7) receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Disruption of lipid rafts inhibits P2X1 receptor-mediated currents and arterial vasoconstriction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Lipid rafts: heterogeneity on the high seas

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Identification of a conserved domain of the HIV-1 transmembrane protein gp41 which interacts with cholesteryl groups

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Molecular physiology of P2X receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

P2X receptor trafficking in neurons is subunit specific.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Pharmacology of cloned P2X receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231676

Lipid rafts are disrupted in mildly inflamed intestinal microenvironments without overt disruption of the epithelial barrier.

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.574699

P2X7 receptor channels allow direct permeation of nanometer-sized dyes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.574699

Potential roles of membrane fluidity and ceramide in hyperthermia and alcohol stimulation of TRAIL apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.574699

Identification of a conserved domain of the HIV-1 transmembrane protein gp41 which interacts with cholesteryl groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.574699

Extracellular ATP triggers IL-1 beta release by activating the purinergic P2Z receptor of human macrophages

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25281740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25281740

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M114.574699

1 reference

2 August 2017

1 reference

2 August 2017

1 reference