(Q52620496)

4 May 2018

title

Lipid rafts are disrupted in mildly inflamed intestinal microenvironments without overt disruption of the epithelial barrier. (English)

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5

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Padraic G. Fallon

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author name string

Rachel V Bowie

1

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4 May 2018

Simona Donatello

2

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Clíona Lyes

3

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Mark B Owens

4

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Lance Hudson

6

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Shaun V Walsh

7

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Diarmuid P O'Donoghue

8

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Sylvie Amu

9

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Sean P Barry

10

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Ann M Hopkins

12

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4 May 2018

publication date

12 January 2012

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4 May 2018

American Journal of Physiology - Gastrointestinal and Liver Physiology

published in

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4 May 2018

volume

302

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4 May 2018

issue

8

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4 May 2018

page(s)

G781-93

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4 May 2018

Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse

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Functions of lipid rafts in biological membranes

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Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

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Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms

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Resolvin E1-induced intestinal alkaline phosphatase promotes resolution of inflammation through LPS detoxification.

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A porous defense: the leaky epithelial barrier in intestinal disease.

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Effects of Lactobacillus salivarius 433118 on intestinal inflammation, immunity status and in vitro colon function in two mouse models of inflammatory bowel disease

21 January 2018

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Rapid reduction of MDCK cell cholesterol by methyl-beta-cyclodextrin alters steady state transepithelial electrical resistance

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Caveolae, DIGs, and the dynamics of sphingolipid-cholesterol microdomains

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Pathologic features and clinical significance of "backwash" ileitis in ulcerative colitis.

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Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function.

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Increased intestinal permeability precedes the onset of Crohn's disease in a subject with familial risk

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Interferon-gamma is causatively involved in experimental inflammatory bowel disease in mice.

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Interleukin-10-deficient mice develop chronic enterocolitis

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Depletion of Caco-2 cell cholesterol disrupts barrier function by altering the detergent solubility and distribution of specific tight-junction proteins

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Methyl-β-Cyclodextrin Increases Permeability of Caco-2 Cell Monolayers by Displacing Specific Claudins from Cholesterol Rich Domains Associated with Tight Junctions

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Interferon-gamma and tumor necrosis factor-alpha disrupt epithelial barrier function by altering lipid composition in membrane microdomains of tight junction

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n-3 polyunsaturated fatty acids prevent disruption of epithelial barrier function induced by proinflammatory cytokines

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Endocytosis of cholera toxin by human enterocytes is developmentally regulated

21 January 2018

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Cholesterol depletion alters detergent-specific solubility profiles of selected tight junction proteins and the phosphorylation of occludin

21 January 2018

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Interferon-gamma directly affects barrier function of cultured intestinal epithelial monolayers

21 January 2018

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Omega-3 polyunsaturated fatty acids ameliorate the severity of ileitis in the senescence accelerated mice (SAM)P1/Yit mice model

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Signalling to and from tight junctions

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Intestinal barrier dysfunction in inflammatory bowel diseases.

21 January 2018

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Expression of tight and adherens junction proteins in ulcerative colitis associated colorectal carcinoma: upregulation of claudin-1, claudin-3, claudin-4, and beta-catenin

21 January 2018

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Characterization of proteins in detergent-resistant membrane complexes from Madin-Darby canine kidney epithelial cells

21 January 2018

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Keynote review: epithelial and endothelial barriers in human disease

21 January 2018

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Modification of tight junction structure and permeability by nutritional means.

21 January 2018

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Intestinal permeability in patients with Crohn's disease and ulcerative colitis and their first degree relatives

21 January 2018

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Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins

21 January 2018

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Lipid rafts: bringing order to chaos

21 January 2018

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Transforming growth factor-beta1 preserves epithelial barrier function: identification of receptors, biochemical intermediates, and cytokine antagonists

21 January 2018

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Epithelial dysfunction associated with the development of colitis in conventionally housed mdr1a-/- mice

21 January 2018

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Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis

21 January 2018

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A detergent-free method for purifying caveolae membrane from tissue culture cells

21 January 2018

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Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains. Detergent-free purification of caveolae microdomains

21 January 2018

1 reference

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Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis.

21 January 2018

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Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2011

Intestinal permeability in patients with Crohn's disease and their first degree relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPGI.00002.2011

Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPGI.00002.2011

Polyunsaturated fatty acids support epithelial barrier integrity and reduce IL-4 mediated permeability in vitro

21 January 2018

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21 January 2018

Identifiers

DOI

10.1152/AJPGI.00002.2011

1 reference

4 May 2018

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4 May 2018