(Q34509761)

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Insulin secretion induced by glucose-dependent insulinotropic polypeptide requires phosphatidylinositol 3-kinase γ in rodent and human β-cells.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25288806%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Insulin secretion induced by glucose-dependent insulinotropic polypeptide requires phosphatidylinositol 3-kinase γ in rodent and human β-cells (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25288806%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

Patrick E. Macdonald

5

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20 February 2020

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Jelena Kolic

1

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20 February 2020

Aliya F Spigelman

2

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20 February 2020

Alannah M Smith

3

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20 February 2020

Jocelyn E Manning Fox

4

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20 February 2020

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6 October 2014

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20 February 2020

Journal of Biological Chemistry

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20 February 2020

289

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20 February 2020

46

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20 February 2020

32109-32120

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Europe PubMed Central

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20 February 2020

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4231687/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Secretion of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes: systematic review and meta-analysis of clinical studies

1 reference

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Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cells

1 reference

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Incretin action in the pancreas: potential promise, possible perils, and pathological pitfalls

1 reference

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7 July 2018

Pharmacology, physiology, and mechanisms of incretin hormone action

1 reference

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7 July 2018

Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin

1 reference

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7 July 2018

PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance

1 reference

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7 July 2018

Two incretin hormones GLP-1 and GIP: comparison of their actions in insulin secretion and β cell preservation.

1 reference

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7 July 2018

Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance

1 reference

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7 July 2018

Snapin mediates incretin action and augments glucose-dependent insulin secretion

1 reference

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7 July 2018

Class IA phosphatidylinositol 3-kinase in pancreatic β cells controls insulin secretion by multiple mechanisms

1 reference

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7 July 2018

Roles of cAMP signalling in insulin granule exocytosis

1 reference

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7 July 2018

Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells

1 reference

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7 July 2018

Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins

1 reference

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7 July 2018

Role of PI3Kdelta and PI3Kgamma in inflammatory arthritis and tissue localization of neutrophils

1 reference

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7 July 2018

Filamentous actin regulates insulin exocytosis through direct interaction with Syntaxin 4.

1 reference

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7 July 2018

Epac: effectors and biological functions

1 reference

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7 July 2018

PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?

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7 July 2018

Actions of glucagon-like peptide-1 on KATP channel-dependent and -independent effects of glucose, sulphonylureas and nateglinide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

The biology of incretin hormones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

Activation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cells

1 reference

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7 July 2018

Novel regulation by Rac1 of glucose- and forskolin-induced insulin secretion in INS-1 beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

Glucagon-like peptide 1 induces pancreatic beta-cell proliferation via transactivation of the epidermal growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

The multiple actions of GLP-1 on the process of glucose-stimulated insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

The glucagon-like peptides

1 reference

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7 July 2018

Glucose-dependent insulinotropic polypeptide stimulates insulin secretion via increased cyclic AMP and [Ca2+]1 and a wortmannin-sensitive signalling pathway

1 reference

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7 July 2018

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

1 reference

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7 July 2018

Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor

1 reference

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7 July 2018

Cloning and functional expression of the human glucagon-like peptide-1 (GLP-1) receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

Cloning and characterization of a G protein-activated human phosphoinositide-3 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

Molecular cloning, functional expression, and signal transduction of the GIP‐receptor cloned from a human insulinoma

1 reference

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7 July 2018

Cloning, functional expression, and chromosomal localization of the human pancreatic islet glucose-dependent insulinotropic polypeptide receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

7 July 2018

Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.577510

21 January 2018

GLP-1: target for a new class of antidiabetic agents?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.577510

21 January 2018

Impaired glucose-stimulated insulin secretion, enhanced intraperitoneal insulin tolerance, and increased beta-cell mass in mice lacking the p110gamma isoform of phosphoinositide 3-kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.577510

21 January 2018

Role of phosphatidylinositol 3-kinasegamma in the beta-cell: interactions with glucagon-like peptide-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.577510

21 January 2018

Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.577510

21 January 2018

Inhibition of phosphoinositide 3-kinase γ attenuates inflammation, obesity, and cardiovascular risk factors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.577510

21 January 2018

Involvement of phosphoinositide 3-kinase gamma, Rac, and PAK signaling in chemokine-induced macrophage migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.577510

21 January 2018

Glucose-stimulated insulin secretion is coupled to the interaction of actin with the t-SNARE (target membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein) complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.577510

21 January 2018

Gastric inhibitory polypeptide receptor, a member of the secretin- vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.577510

21 January 2018

Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

27 October 2018

Tissue distribution and subcellular localization of a G-protein activated phosphoinositide 3-kinase. An immunohistochemical study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4231687

27 October 2018

Reduced Incretin Effect in Type 2 Diabetes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.577510

21 January 2018

Pancreatic Beta-Cell Web: Its Possible Role in Insulin Secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/25288806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The insulinotropic action of gastric inhibitory polypeptide in the perfused isolated rat pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/25288806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced incretin effect in type 2 (non-insulin-dependent) diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25288806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose activates both K(ATP) channel-dependent and K(ATP) channel-independent signaling pathways in human islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/25288806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of pancreatic -cell insulin secretion by actin cytoskeleton remodelling: role of gelsolin and cooperation with the MAPK signalling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/25288806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Effect of incretin hormones GIP and GLP-1 for the pathogenesis of type 2 diabetes mellitus]

1 reference

https://pubmed.ncbi.nlm.nih.gov/25288806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/25288806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct and opposing roles for the phosphatidylinositol 3-OH kinase catalytic subunits p110α and p110β in the regulation of insulin secretion from rodent and human beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25288806

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M114.577510

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25288806%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25288806%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25288806%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

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