(Q34513677)

2 August 2017

title

Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2). (English)

1 reference

2 August 2017

5

Ulla M Wewer

0 references

author name string

Marie Kveiborg

1

1 reference

2 August 2017

Jonas Jacobsen

2

1 reference

2 August 2017

Meng-Huee Lee

3

1 reference

2 August 2017

Hideaki Nagase

4

1 reference

2 August 2017

Ulla M Wewer

5

1 reference

2 August 2017

Gillian Murphy

6

1 reference

2 August 2017

language of work or name

English

0 references

publication date

1 August 2010

1 reference

2 August 2017

1 reference

2 August 2017

volume

430

1 reference

2 August 2017

issue

1

1 reference

2 August 2017

page(s)

79-86

1 reference

ADAM12 localizes with c-Src to actin-rich structures at the cell periphery and regulates Src kinase activity

2 August 2017

cites work

1 reference

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Targeting ADAM12 in human disease: head, body or tail?

7 July 2018

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The ADAMs: signalling scissors in the tumour microenvironment

7 July 2018

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Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex

7 July 2018

1 reference

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Cellular roles of ADAM12 in health and disease.

7 July 2018

1 reference

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The isolated N-terminal domains of TIMP-1 and TIMP-3 are insufficient for ADAM10 inhibition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025530

Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases.

7 July 2018

1 reference

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Proteolytic processing of delta-like 1 by ADAM proteases

7 July 2018

1 reference

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Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx

7 July 2018

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MT1-MMP shedding involves an ADAM and is independent of its localization in lipid rafts

7 July 2018

1 reference

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Towards third generation matrix metalloproteinase inhibitors for cancer therapy

7 July 2018

1 reference

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Structure and function of matrix metalloproteinases and TIMPs

7 July 2018

1 reference

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Total conversion of tissue inhibitor of metalloproteinase (TIMP) for specific metalloproteinase targeting: fine-tuning TIMP-4 for optimal inhibition of tumor necrosis factor-{alpha}-converting enzyme

7 July 2018

1 reference

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Regulation of ADAM12 cell-surface expression by protein kinase C epsilon

7 July 2018

1 reference

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Phenotypic analysis of Meltrin alpha (ADAM12)-deficient mice: involvement of Meltrin alpha in adipogenesis and myogenesis

7 July 2018

1 reference

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E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A)

7 July 2018

1 reference

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Mapping and characterization of the functional epitopes of tissue inhibitor of metalloproteinases (TIMP)-3 using TIMP-1 as the scaffold: a new frontier in TIMP engineering

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025530

The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025530

Engineering N-terminal domain of tissue inhibitor of metalloproteinase (TIMP)-3 to be a better inhibitor against tumour necrosis factor-alpha-converting enzyme

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025530

ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025530

Remarkable roles of proteolysis on and beyond the cell surface

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025530

Identification of the (183)RWTNNFREY(191) region as a critical segment of matrix metalloproteinase 1 for the expression of collagenolytic activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025530

Specific sequence elements are required for the expression of functional tumor necrosis factor-alpha-converting enzyme (TACE).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025530

Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025530

Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025530

A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025530

17 The kinetics of reversible tight-binding inhibition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3025530

ADAMs, a disintegrin and metalloproteinases, mediate shedding of oxytocinase

7 July 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100649

Catalytic properties of ADAM12 and its domain deletion mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100649

Unveiling the surface epitopes that render tissue inhibitor of metalloproteinase-1 inactive against membrane type 1-matrix metalloproteinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100649

Threonine 98, the pivotal residue of tissue inhibitor of metalloproteinases (TIMP)-1 in metalloproteinase recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100649

Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100649

Fluorescent substrates for the proteinases ADAM17, ADAM10, ADAM8, and ADAM12 useful for high-throughput inhibitor screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100649

ADAM12 Is a Four-leafed Clover

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20100649

TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5)

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20533908

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Folding and characterization of the amino-terminal domain of human tissue inhibitor of metalloproteinases-1 (TIMP-1) expressed at high yield in E. coli

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20533908

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20533908

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1042/BJ20100649

1 reference

2 August 2017

1 reference

2 August 2017

1 reference