(Q34518175)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

0 references

0 references

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Joana A Revez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Joseph E. Powell

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

David L. Duffy

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Eco de Geus

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

David A Hinds

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Nick Martin

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Grant W. Montgomery

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Manuel A Ferreira

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

9

B W Penninx

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

12

D I Boomsma

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

author name string

L Bain

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

B Chapman

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

R Jansen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

J Y Tung

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

AAGC Collaborators

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

publication date

15 August 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

page(s)

441-446

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

7 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

The Adult Netherlands Twin Register: twenty-five years of survey and biological data collection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Role of IL-6 in asthma and other inflammatory pulmonary diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

An integrated map of genetic variation from 1,092 human genomes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

An integrated encyclopedia of DNA elements in the human genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

The Brisbane Systems Genetics Study: genetical genomics meets complex trait genetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

A large-scale, consortium-based genomewide association study of asthma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Heritability of renal function and inflammatory markers in adult male twins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

METAL: fast and efficient meta-analysis of genomewide association scans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Recent advances in the pathophysiology of asthma

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Elevation of IL-6 in the allergic asthmatic airway is independent of inflammation but associates with loss of central airway function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Common variants in the trichohyalin gene are associated with straight hair in Europeans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

A flexible and accurate genotype imputation method for the next generation of genome-wide association studies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

A genome-wide association study identifies protein quantitative trait loci (pQTLs)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Genome-wide association of major depression: description of samples for the GAIN Major Depressive Disorder Study: NTR and NESDA biobank projects

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Pathological role of IL-6 in the experimental allergic bronchial asthma in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

The soluble interleukin-6 receptor is generated by shedding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Soluble receptors for cytokines and growth factors: generation and biological function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Molecular cloning and expression of an IL-6 signal transducer, gp130

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233139

Endogenous and exogenous IL-6 inhibit aeroallergen-induced Th2 inflammation.

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2013.38

Differential expression of CD126 and CD130 mediates different STAT-3 phosphorylation in CD4+CD25- and CD25high regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2013.38

Polymorphisms in the IL-6 receptor (IL-6R) gene: strong evidence that serum levels of soluble IL-6R are genetically influenced.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2013.38

Variance components analyses of multiple asthma traits in a large sample of Australian families ascertained through a twin proband.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2013.38

A genome-wide scan for naevus count: linkage to CDKN2A and to other chromosome regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2013.38

The soluble human IL-6 receptor. Mutational characterization of the proteolytic cleavage site

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23945879

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23945879

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/GENE.2013.38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23945879%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

23945879

1 reference