(Q34520401)

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Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate

scientific article published on November 15, 2010

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2 August 2017

Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate (English)

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2 August 2017

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Connie Cheung

1

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Europe PubMed Central

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2 August 2017

Shea Loy

2

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2 August 2017

Guang Xun Li

3

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2 August 2017

Anna B. Liu

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081470

27 August 2024

Chung S. Yang

5

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27 August 2024

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15 November 2010

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2 August 2017

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27 August 2024

http://carcin.oxfordjournals.org/cgi/content/abstract/32/2/233

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27 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21081470/?tool=EBI

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27 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21081470/pdf/?tool=EBI

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27 August 2024

https://europepmc.org/articles/PMC3026842

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Europe PubMed Central

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081470

27 August 2024

https://europepmc.org/articles/PMC3026842?pdf=render

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27 August 2024

https://doi.org/10.1093/carcin/bgq235

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081470

27 August 2024

http://academic.oup.com/carcin/article-pdf/32/2/233/17288779/bgq235.pdf

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1 reference

10.1093/CARCIN/BGQ235

https://api.crossref.org/works/10.1093/CARCIN/BGQ235

27 August 2024

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Europe PubMed Central

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2 August 2017

32

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Europe PubMed Central

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2 August 2017

2

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Europe PubMed Central

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2 August 2017

233-239

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Europe PubMed Central

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2 August 2017

A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this association

1 reference

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Western-style diets induce oxidative stress and dysregulate immune responses in the colon in a mouse model of sporadic colon cancer.

1 reference

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1 reference

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1 reference

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Inflammation and atrophy precede prostatic neoplasia in a PhIP-induced rat model

1 reference

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Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus

1 reference

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High-grade prostatic intraepithelial neoplasia

1 reference

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7 July 2018

A rat colon cancer model induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, PhIP.

1 reference

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7 July 2018

Role of nitric oxide in carcinogenesis and tumour progression

1 reference

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7 July 2018

More frequent beta-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026842

7 July 2018

Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026842

7 July 2018

Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.

1 reference

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7 July 2018

Effects of long-term feeding with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in C57BL/ByA and E mu-pim-1 mice.

1 reference

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7 July 2018

Assessment of the human exposure to heterocyclic amines

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7 July 2018

Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes

1 reference

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7 July 2018

Efficient method for rapid induction of aberrant crypt foci in rats with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

1 reference

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7 July 2018

Signal transduction through beta-catenin and specification of cell fate during embryogenesis

1 reference

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7 July 2018

Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis.

1 reference

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7 July 2018

Exposure to heterocyclic amines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026842

7 July 2018

Metabolic activation pathway for the formation of DNA adducts of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat extrahepatic tissues.

1 reference

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7 July 2018

Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes.

1 reference

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7 July 2018

The role of fat and calcium in the production of foci of aberrant crypts in the colon of rats fed 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine

1 reference

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Metabolic activation of N-hydroxy arylamines and N-hydroxy heterocyclic amines by human sulfotransferase(s).

1 reference

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7 July 2018

Species differences in the biotransformation of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by hepatic microsomes and cytosols from humans, rats, and mice

1 reference

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Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings

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Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

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Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon

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Induction of lymphoma in CDF1 mice by the food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

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Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2.

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Colonic adenocarcinomas rapidly induced by the combined treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate in male ICR mice possess beta-catenin gene mutations and increases immunoreactivity for beta-catenin, c

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Re: "Fried foods and the risk of colon cancer".

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27 October 2018

Identifiers

10.1093/CARCIN/BGQ235

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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