(Q34520401)

English

Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

Rapid induction of colon carcinogenesis in CYP1A-humanized mice by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

1 reference

based on heuristic

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author name string

Connie Cheung

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Shea Loy

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Guang Xun Li

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Anna B Liu

4

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Europe PubMed Central

PubMed publication ID

2 August 2017

Chung S Yang

5

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Europe PubMed Central

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2 August 2017

language of work or name

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publication date

15 November 2010

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Europe PubMed Central

PubMed publication ID

2 August 2017

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Europe PubMed Central

PubMed publication ID

2 August 2017

32

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Europe PubMed Central

PubMed publication ID

2 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

233-239

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Europe PubMed Central

PubMed publication ID

2 August 2017

A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this association

1 reference

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Molecular origins of cancer: Molecular basis of colorectal cancer

1 reference

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Western-style diets induce oxidative stress and dysregulate immune responses in the colon in a mouse model of sporadic colon cancer.

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Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.

1 reference

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Generation of 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-) mouse line

1 reference

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Inflammation and atrophy precede prostatic neoplasia in a PhIP-induced rat model

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The canonical Wnt signalling pathway and its APC partner in colon cancer development

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7 July 2018

A rat colon cancer model induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, PhIP.

1 reference

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Role of nitric oxide in carcinogenesis and tumour progression

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7 July 2018

More frequent beta-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026842

7 July 2018

Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026842

7 July 2018

Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.

1 reference

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7 July 2018

Effects of long-term feeding with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in C57BL/ByA and E mu-pim-1 mice.

1 reference

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7 July 2018

Assessment of the human exposure to heterocyclic amines

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Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes

1 reference

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7 July 2018

Efficient method for rapid induction of aberrant crypt foci in rats with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

1 reference

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Signal transduction through beta-catenin and specification of cell fate during embryogenesis

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Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis.

1 reference

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7 July 2018

Exposure to heterocyclic amines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026842

7 July 2018

Metabolic activation pathway for the formation of DNA adducts of the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat extrahepatic tissues.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3026842

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Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes.

1 reference

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The role of fat and calcium in the production of foci of aberrant crypts in the colon of rats fed 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine

1 reference

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Metabolic activation of N-hydroxy arylamines and N-hydroxy heterocyclic amines by human sulfotransferase(s).

1 reference

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Species differences in the biotransformation of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by hepatic microsomes and cytosols from humans, rats, and mice

1 reference

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Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings

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Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

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Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon

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Induction of lymphoma in CDF1 mice by the food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

1 reference

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1 reference

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Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2.

1 reference

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1 reference

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Colonic adenocarcinomas rapidly induced by the combined treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate in male ICR mice possess beta-catenin gene mutations and increases immunoreactivity for beta-catenin, c

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Expression of beta-catenin and full-length APC protein in normal and neoplastic colonic tissues.

1 reference

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27 October 2018

Macromolecular adduct formation and metabolism of heterocyclic amines in humans and rodents at low doses.

1 reference

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1 reference

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27 October 2018

Re: "Fried foods and the risk of colon cancer".

1 reference

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27 October 2018

Identifiers

10.1093/CARCIN/BGQ235

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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