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Generation of 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-) mouse line
scientific article
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
title
Generation of 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-) mouse line
(English)
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
author
Nadine Dragin
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
author name string
Shigeyuki Uno
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
Bin Wang
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
Timothy P Dalton
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
Daniel W Nebert
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
language of work or name
English
0 references
publication date
6 June 2007
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
published in
Biochemical and Biophysical Research Communications
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
volume
359
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
issue
3
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
page(s)
635-642
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
cites work
Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
The role of cytochrome P450 enzymes in endogenous signalling pathways and environmental carcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Systematic analysis of head-to-head gene organization: evolutionary conservation and potential biological relevance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Proteasome activator PA200 is required for normal spermatogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Mosaic analysis with double markers in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Interspecies metabolism of heterocyclic aromatic amines and the uncertainties in extrapolation of animal toxicity data for human risk assessment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Engineering chromosomal rearrangements in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
How knockout mouse lines will be used to study the role of drug-metabolizing enzymes and their receptors during reproduction and development, and in environmental toxicity, cancer, and oxidative stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Cre-mediated site-specific translocation between nonhomologous mouse chromosomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Relationship between "aromatic hydrocarbon responsiveness" and the survival times in mice treated with various drugs and environmental compounds
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
2 October 2017
Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
27 July 2018
Human cDNA-expressed cytochrome P450 IA2: mutagen activation and substrate specificity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
27 July 2018
Constitutive and inducible forms of cytochrome P450 from hepatic mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
27 July 2018
Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
23 September 2018
Theophylline pharmacokinetics: comparison of Cyp1a1(-/-) and Cyp1a2(-/-) knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
23 September 2018
Balancer-Cre transgenic mouse germ cells direct the incomplete resolution of a tri-loxP-targeted Cyp1a1 allele, producing a conditional knockout allele.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
23 September 2018
Uroporphyrin accumulation in hepatoma cells expressing human or mouse CYP1A2: relation to the role of CYP1A2 in human porphyria cutanea tarda
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
23 September 2018
Dual renin gene targeting by Cre-mediated interchromosomal recombination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
23 September 2018
Cancer chemotherapy using suicide genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648
retrieved
23 September 2018
Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17560947
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Efficient removal of loxP-flanked DNA sequences in a gene-targeted locus by transient expression of Cre recombinase in fertilized eggs
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17560947
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.BBRC.2007.05.202
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
PMCID
1994648
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
PubMed ID
17560947
1 reference
stated in
Europe PubMed Central
PMCID
1994648
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 December 2019
ResearchGate publication ID
6275913
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