(Q34520921)

2 August 2017

Nonlinear signalling networks and cell-to-cell variability transform external signals into broadly distributed or bimodal responses (English)

1 reference

2 August 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Walter Kolch

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Boris Kholodenko

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Maciej Dobrzyński

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Marc R. Birtwistle

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Alex von Kriegsheim

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Alex Cheong

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Alfonso Blanco Fernández

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

publication date

1 September 2014

1 reference

Journal of the Royal Society Interface

2 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

98

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

20140383

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

Crosstalk and signaling switches in mitogen-activated protein kinase cascades

10 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Fractional proliferation: a method to deconvolve cell population dynamics from single-cell data

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Exploring the contextual sensitivity of factors that determine cell-to-cell variability in receptor-mediated apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Hypoxia-inducible factors in physiology and medicine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

A two-dimensional ERK-AKT signaling code for an NGF-triggered cell-fate decision

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Dynamic modelling of oestrogen signalling and cell fate in breast cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Bimodal gene expression in noncooperative regulatory systems

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Noisy-threshold control of cell death.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Signalling ballet in space and time

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Design of versatile biochemical switches that respond to amplitude, duration, and spatial cues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Non-genetic cell-to-cell variability and the consequences for pharmacology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

A stochastic spectral analysis of transcriptional regulatory cascades

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Dynamic proteomics of individual cancer cells in response to a drug.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Analytical distributions for stochastic gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Variability and robustness in T cell activation from regulated heterogeneity in protein levels

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Information flow and optimization in transcriptional regulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Quantification of mRNA in single cells and modelling of RT-qPCR induced noise

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Engineering synthetic signaling proteins with ultrasensitive input/output control

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Phenotypic consequences of promoter-mediated transcriptional noise

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Stochastic mRNA synthesis in mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Cell-signalling dynamics in time and space

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Stochasticity in gene expression: from theories to phenotypes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Stochastic simulations of the origins and implications of long-tailed distributions in gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Stochastic amplification and signaling in enzymatic futile cycles through noise-induced bistability with oscillations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

RNA dynamics in live Escherichia coli cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Oxygen sensing by HIF hydroxylases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Noise in eukaryotic gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

A conserved family of prolyl-4-hydroxylases that modify HIF

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Construction of a genetic toggle switch in Escherichia coli

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Ultrasensitivity in the mitogen-activated protein kinase cascade

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4233687

Origins of stochastic intracellular processes and consequences for cell-to-cell variability and cellular survival strategies.

7 July 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSIF.2014.0383

Probing gene expression in live cells, one protein molecule at a time.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSIF.2014.0383

An investigation into the population abundance distribution of mRNAs, proteins, and metabolites in biological systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSIF.2014.0383

Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSIF.2014.0383

A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSIF.2014.0383

A new look at the statistical model identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSIF.2014.0383

Mammalian protein expression noise: scaling principles and the implications for knockdown experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1098%2FRSIF.2014.0383

A simple coding procedure enhances a neuron's information capacity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24966234

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1098/RSIF.2014.0383

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24966234%20AND%20SRC:MED&resulttype=core&format=json