(Q34393131)

1 August 2017

Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise (English)

1 reference

1 August 2017

7

1 reference

1 August 2017

8

1 reference

1 August 2017

9

1 reference

1 August 2017

Edita Aksamitiene

4

0 references

Maciej Dobrzyński

Maciej Dobrzyński

5

0 references

Jens Rauch

Jens Rauch

2

0 references

Anatoly Kiyatkin

Anatoly Kiyatkin

3

0 references

Marc R. Birtwistle

Marc R Birtwistle

1

0 references

Jan B. Hoek

Jan B Hoek

6

0 references

publication date

24 August 2012

1 reference

1 August 2017

1 reference

1 August 2017

6

1 reference

1 August 2017

109

1 reference

https://scigraph.springernature.com/pub.10.1186/1752-0509-6-109

1 August 2017

0 references

cites work

Prolactin-stimulated activation of ERK1/2 mitogen-activated protein kinases is controlled by PI3-kinase/Rac/PAK signaling pathway in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Strong negative feedback from Erk to Raf confers robustness to MAPK signalling.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Biology using engineering tools: the negative feedback amplifier

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Ligand-specific c-Fos expression emerges from the spatiotemporal control of ErbB network dynamics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Four-dimensional dynamics of MAPK information processing systems.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

The incoherent feedforward loop can provide fold-change detection in gene regulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Dynamics and variability of ERK2 response to EGF in individual living cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Non-genetic cell-to-cell variability and the consequences for pharmacology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Differential effects of EGFR ligands on endocytic sorting of the receptor.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Protein dynamics in individual human cells: experiment and theory

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Systems-level interactions between insulin-EGF networks amplify mitogenic signaling.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Digital signaling and hysteresis characterize ras activation in lymphoid cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Origin of the sharp boundary that discriminates positive and negative selection of thymocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Analytical distributions for stochastic gene expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Activation of the MAPK module from different spatial locations generates distinct system outputs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Long-range signaling by phosphoprotein waves arising from bistability in protein kinase cascades

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Stochastic mRNA synthesis in mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Noise in protein expression scales with natural protein abundance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Phospho-proteomic immune analysis by flow cytometry: from mechanism to translational medicine at the single-cell level

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Cell-signalling dynamics in time and space

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Noise in gene expression: origins, consequences, and control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Regulated cell-to-cell variation in a cell-fate decision system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Graded mitogen-activated protein kinase activity precedes switch-like c-Fos induction in mammalian cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Quantitative analysis of signaling networks.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

The dynamics of cell cycle regulation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Stochastic focusing: fluctuation-enhanced sensitivity of intracellular regulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Stochastic mechanisms in gene expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Ultrasensitivity in the mitogen-activated protein kinase cascade

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

An amplified sensitivity arising from covalent modification in biological systems

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3484110

Subcellular localization determines MAP kinase signal output.

6 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-6-109

Stochastic modelling for quantitative description of heterogeneous biological systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-6-109

Effects of molecular memory and bursting on fluctuations in gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-6-109

Probing gene expression in live cells, one protein molecule at a time.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-6-109

Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-6-109

Stochastic protein expression in individual cells at the single molecule level

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1752-0509-6-109

Regulation of ras signaling dynamics by Sos-mediated positive feedback

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22920937

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Linking stochastic dynamics to population distribution: an analytical framework of gene expression

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22920937

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Intracellular trafficking of epidermal growth factor family ligands is directly influenced by the pH sensitivity of the receptor/ligand interaction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22920937

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1752-0509-6-109

1 reference

journals/bmcsb/BirtwistleRKADHKOK12

1 August 2017

1 reference

DBLP Dataset 2021-01-02

Dimensions Publication ID

28 January 2021

0 references

1 reference

1 August 2017

1 reference

PubMed ID

22920937