(Q34929087)

5 August 2017

title

Digital signaling and hysteresis characterize ras activation in lymphoid cells (English)

1 reference

5 August 2017

6

Arthur Weiss

1 reference

5 August 2017

Jeroen P Roose

8

1 reference

ORCID Public Data File 2021

author name string

Jayajit Das

1

1 reference

5 August 2017

Mary Ho

2

1 reference

5 August 2017

Julie Zikherman

3

1 reference

5 August 2017

Christopher Govern

4

1 reference

5 August 2017

Ming Yang

5

1 reference

5 August 2017

Arup K Chakraborty

7

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 January 2009

1 reference

5 August 2017

1 reference

5 August 2017

volume

136

1 reference

5 August 2017

issue

2

1 reference

5 August 2017

page(s)

337-351

1 reference

Origin of the sharp boundary that discriminates positive and negative selection of thymocytes

5 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

RasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Plasma membrane nanoswitches generate high-fidelity Ras signal transduction

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

A Ras-induced conformational switch in the Ras activator Son of sevenless

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Spontaneous separation of bi-stable biochemical systems into spatial domains of opposite phases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Oligomerization of signaling complexes by the multipoint binding of GRB2 to both LAT and SOS1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Compartmentalized Ras/MAPK signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Modeling T cell antigen discrimination based on feedback control of digital ERK responses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Structural analysis of autoinhibition in the Ras activator Son of sevenless

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Positive and negative selection of T cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Untangling the wires: a strategy to trace functional interactions in signaling and gene networks

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

RasGRP is essential for mouse thymocyte differentiation and TCR signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

RasGRP links T-cell receptor signaling to Ras

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Ras regulation and function in lymphocytes.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Emergent properties of networks of biological signaling pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Regulation of Sos activity by intramolecular interactions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Stochastic mechanisms in gene expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Ligand-receptor interactions required for commitment to the activation of the interleukin 2 gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Increasing complexity of Ras signaling.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662698

Circadian clocks limited by noise

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19167334

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antigen receptors on immature, but not mature, B and T cells are coupled to cytosolic phospholipase A2 activation: expression and activation of cytosolic phospholipase A2 correlate with lymphocyte maturation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19167334

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of ras signaling dynamics by Sos-mediated positive feedback

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19167334

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2008.11.051

1 reference

5 August 2017

1 reference

5 August 2017

1 reference