(Q37698293)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20182652%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

review article

1 reference

title

Four-dimensional dynamics of MAPK information processing systems (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20182652%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

main subject

information processing

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20182652%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Marc R. Birtwistle

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20182652%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Marc R Birtwistle

series ordinal

2

1 reference

22 August 2017

1 July 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20182652%20AND%20SRC:MED&resulttype=core&format=json

Wiley interdisciplinary reviews. Systems biology and medicine

18 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20182652%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20182652%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20182652%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

28-44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20182652%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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23 August 2017

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Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate

23 August 2017

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23 August 2017

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Long-range signaling by phosphoprotein waves arising from bistability in protein kinase cascades

23 August 2017

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Modelling microtubule patterns

23 August 2017

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An intrinsic cell cycle checkpoint pathway mediated by MEK and ERK in Drosophila.

23 August 2017

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Bistability from double phosphorylation in signal transduction. Kinetic and structural requirements

23 August 2017

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MAPK signalling: ERK5 versus ERK1/2.

23 August 2017

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Inhibition of ERK-MAP kinase signaling by RSK during Drosophila development

23 August 2017

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Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops

23 August 2017

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Dual role for membrane localization in yeast MAP kinase cascade activation and its contribution to signaling fidelity.

23 August 2017

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Cell-signalling dynamics in time and space

23 August 2017

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D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells

23 August 2017

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Scaffold proteins in MAP kinase signaling: more than simple passive activating platforms.

23 August 2017

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The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

23 August 2017

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Bistability, stochasticity, and oscillations in the mitogen-activated protein kinase cascade

23 August 2017

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Modeling T cell antigen discrimination based on feedback control of digital ERK responses

23 August 2017

1 reference

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Coordinating ERK/MAPK signalling through scaffolds and inhibitors

23 August 2017

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Protein phosphatases in MAPK signalling: we keep learning from yeast.

23 August 2017

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Systems-level dissection of the cell-cycle oscillator: bypassing positive feedback produces damped oscillations

23 August 2017

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When kinases meet mathematics: the systems biology of MAPK signalling

23 August 2017

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Identification of major ERK-related phosphorylation sites in Gab1.

23 August 2017

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Signaling in small subcellular volumes. II. Stochastic and diffusion effects on synaptic network properties

23 August 2017

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Signaling in small subcellular volumes. I. Stochastic and diffusion effects on individual pathways

23 August 2017

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Roles of MAP kinase cascades in Caenorhabditis elegans

23 August 2017

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Not just a sink: endosomes in control of signal transduction

23 August 2017

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Quantitative analysis of signaling networks.

23 August 2017

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Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase

23 August 2017

1 reference

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Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

23 August 2017

1 reference

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Mitogen-activated protein kinase feedback phosphorylation regulates MEK1 complex formation and activation during cellular adhesion

23 August 2017

1 reference

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Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems

23 August 2017

1 reference

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Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades

23 August 2017

1 reference

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Retrograde transport of neurotrophins: fact and function

23 August 2017

1 reference

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Signaling endosome hypothesis: A cellular mechanism for long distance communication

23 August 2017

1 reference

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A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration.

23 August 2017

1 reference

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A positive-feedback-based bistable 'memory module' that governs a cell fate decision

23 August 2017

1 reference

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Four-dimensional organization of protein kinase signaling cascades: the roles of diffusion, endocytosis and molecular motors

23 August 2017

1 reference

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Trafficking of the ErbB receptors and its influence on signaling

23 August 2017

1 reference

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Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2.

23 August 2017

1 reference

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Hysteresis drives cell-cycle transitions in Xenopus laevis egg extracts

23 August 2017

1 reference

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Computational approaches to cellular rhythms

23 August 2017

1 reference

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Expression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational control

23 August 2017

1 reference

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Mixed-lineage kinase control of JNK and p38 MAPK pathways

23 August 2017

1 reference

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Signal transduction and endocytosis: close encounters of many kinds

23 August 2017

1 reference

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MAP kinase cascade signaling and endocytic trafficking: a marriage of convenience?

23 August 2017

1 reference

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KSR is a scaffold required for activation of the ERK/MAPK module

23 August 2017

1 reference

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Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells

23 August 2017

1 reference

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Mammalian MAP kinase signalling cascades

23 August 2017

1 reference

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p38 MAPK signalling cascades: ancient roles and new functions

23 August 2017

1 reference

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Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Why cytoplasmic signalling proteins should be recruited to cell membranes.

23 August 2017

1 reference

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Signal transduction: hanging on a scaffold.

23 August 2017

1 reference

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Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation

23 August 2017

1 reference

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Xenopus oocyte maturation: new lessons from a good egg.

23 August 2017

1 reference

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Emergent properties of networks of biological signaling pathways

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Dimerization of Ste5, a mitogen-activated protein kinase cascade scaffold protein, is required for signal transduction

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Ultrasensitivity in the mitogen-activated protein kinase cascade

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Downregulation of the Ras activation pathway by MAP kinase phosphorylation of Sos.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

An amplified sensitivity arising from covalent modification in biological systems

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Ultrasensitivity in biochemical systems controlled by covalent modification. Interplay between zero-order and multistep effects

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Mutational removal of the Thr669 and Ser671 phosphorylation sites alters substrate specificity and ligand-induced internalization of the epidermal growth factor receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Dynamics of the p53-Mdm2 feedback loop in individual cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Bistability in the JNK cascade

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Molecular identification and functional characterization of a Drosophila dual-specificity phosphatase DMKP-4 which is involved in PGN-induced activation of the JNK pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

The molecular scaffold KSR1 regulates the proliferative and oncogenic potential of cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Stathmin-tubulin interaction gradients in motile and mitotic cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

The JNK cascade as a biochemical switch in mammalian cells: ultrasensitive and all-or-none responses

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

FGF induces oscillations of Hes1 expression and Ras/ERK activation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Mathematical and computational analysis of adaptation via feedback inhibition in signal transduction pathways

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Signal processing at the Ras circuit: what shapes Ras activation patterns?

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Molecular interpretation of ERK signal duration by immediate early gene products

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Ste5 RING-H2 domain: role in Ste4-promoted oligomerization for yeast pheromone signaling

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Positive feedback between MAP kinase and Mos during Xenopus oocyte maturation.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Numerical analysis of a comprehensive model of M-phase control in Xenopus oocyte extracts and intact embryos.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Negative Feedback Regulation and Desensitization of Insulin- and Epidermal Growth Factor-stimulated p21ras Activation

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Signaling cascades as cellular devices for spatial computations

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Drosophila eggshell is patterned by sequential action of feedforward and feedback loops

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Multistationarity in the activation of a MAPK: parametrizing the relevant region in parameter space

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Bistable MAP kinase activity: a plausible mechanism contributing to maintenance of late long-term potentiation.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

GLH-1, the C. elegans P granule protein, is controlled by the JNK KGB-1 and by the COP9 subunit CSN-5.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Untangling the signalling wires

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Steady state and (bi-) stability evaluation of simple protease signalling networks.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Vimentin binding to phosphorylated Erk sterically hinders enzymatic dephosphorylation of the kinase.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Potential for control of signaling pathways via cell size and shape

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Effects of sequestration on signal transduction cascades.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Subcellular localization determines MAP kinase signal output.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Fast vesicle transport in PC12 neurites: velocities and forces

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

How robust are switches in intracellular signaling cascades?

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Spatial requirements for TrkA kinase activity in the support of neuronal survival and axon growth in rat sympathetic neurons

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Mathematical models of protein kinase signal transduction.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Retrograde support of neuronal survival without retrograde transport of nerve growth factor

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Role of scaffolds in MAP kinase pathway specificity revealed by custom design of pathway-dedicated signaling proteins.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Spatial gradients of cellular phospho-proteins.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Quantification of information transfer via cellular signal transduction pathways.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

How responses get more switch-like as you move down a protein kinase cascade.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

SOS phosphorylation and disassociation of the Grb2-SOS complex by the ERK and JNK signaling pathways

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Dynamic stability of steady states and static stabilization in unbranched metabolic pathways.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826817

Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades

1 September 2018

1 reference

Why do protein kinase cascades have more than one level?

21 January 2018

1 reference

Principles behind the multifarious control of signal transduction

21 January 2018

1 reference

Dynamics of the Ras/ERK MAPK Cascade as Monitored by Fluorescent Probes

21 January 2018

1 reference

Oscillatory dynamics arising from competitive inhibition and multisite phosphorylation

21 January 2018

1 reference

Differential feedback regulation of the MAPK cascade underlies the quantitative differences in EGF and NGF signalling in PC12 cells

21 January 2018

1 reference

Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve

21 January 2018

1 reference

12 December 2020

The dual specificity mitogen-activated protein kinase phosphatase-1 and -2 are induced by the p42/p44MAPK cascade

1 reference

12 December 2020

Prediction and validation of the distinct dynamics of transient and sustained ERK activation

1 reference

12 December 2020

Gradients in the self-organization of the mitotic spindle

1 reference

12 December 2020

Thapsigargin, a novel promoter, phosphorylates the epidermal growth factor receptor at threonine 669

1 reference

12 December 2020

Isolation and characterization of two growth factor-stimulated protein kinases that phosphorylate the epidermal growth factor receptor at threonine 669

1 reference

12 December 2020

Multistability: a major means of differentiation and evolution in biological systems

1 reference

12 December 2020

Substrate Recognition Domains within Extracellular Signal-regulated Kinase Mediate Binding and Catalytic Activation of Mitogen-activated Protein Kinase Phosphatase-3

1 reference

12 December 2020

Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling

1 reference

12 December 2020

Identifiers

DOI

10.1002/WSBM.16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20182652%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20182652%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

20182652

1 reference