(Q51856579)

14 April 2018

review article

1 reference

title

Stochastic modelling for quantitative description of heterogeneous biological systems. (English)

1 reference

14 April 2018

Darren J Wilkinson

1

0 references

publication date

1 February 2009

1 reference

14 April 2018

published in

Nature Reviews Genetics

1 reference

14 April 2018

volume

10

1 reference

14 April 2018

issue

2

1 reference

14 April 2018

page(s)

122-133

1 reference

14 April 2018

https://scigraph.springernature.com/pub.10.1038/nrg2509

exact match

0 references

cites work

Computational systems biology

1 reference

It's a noisy business! Genetic regulation at the nanomolar scale

31 March 2020

1 reference

UV Irradiation Stimulates Levels of p53 Cellular Tumor Antigen in Nontransformed Mouse Cells

31 March 2020

1 reference

Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study

31 March 2020

1 reference

Dynamics of the p53-Mdm2 feedback loop in individual cells

31 March 2020

1 reference

Oscillations and variability in the p53 system

31 March 2020

1 reference

Mdm2 promotes the rapid degradation of p53

31 March 2020

1 reference

Unlocking the Mdm2-p53 loop: ubiquitin is the key.

31 March 2020

1 reference

The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models

31 March 2020

1 reference

A plausible model for the digital response of p53 to DNA damage.

31 March 2020

1 reference

Explaining oscillations and variability in the p53-Mdm2 system

31 March 2020

1 reference

Single cell resolution in regulation of gene expression

31 March 2020

1 reference

Living with noisy genes: how cells function reliably with inherent variability in gene expression

31 March 2020

1 reference

Selection to minimise noise in living systems and its implications for the evolution of gene expression

31 March 2020

1 reference

Cell-to-cell stochastic variation in gene expression is a complex genetic trait.

31 March 2020

1 reference

Noise in gene expression: origins, consequences, and control

31 March 2020

1 reference

Tuning gene expression to changing environments: from rapid responses to evolutionary adaptation

31 March 2020

1 reference

Exact stochastic simulation of coupled chemical reactions

31 March 2020

1 reference

Stochastic mechanisms in gene expression

31 March 2020

1 reference

Quantitation of transcription and clonal selection of single living cells with beta-lactamase as reporter

31 March 2020

1 reference

Algorithms and software for stochastic simulation of biochemical reacting systems

31 March 2020

1 reference

Stochastic focusing: fluctuation-enhanced sensitivity of intracellular regulation

31 March 2020

1 reference

Stochastic aspects of oscillatory Ca2+ dynamics in hepatocytes.

31 March 2020

1 reference

Stochastic protein expression in individual cells at the single molecule level

31 March 2020

1 reference

Colored extrinsic fluctuations and stochastic gene expression

31 March 2020

1 reference

Efficient Exact Stochastic Simulation of Chemical Systems with Many Species and Many Channels

31 March 2020

1 reference

Approximate accelerated stochastic simulation of chemically reacting systems

31 March 2020

1 reference

Hybrid simulation of cellular behavior

31 March 2020

1 reference

Bridging the gap between stochastic and deterministic regimes in the kinetic simulations of the biochemical reaction networks.

31 March 2020

1 reference

Stochastic chemical kinetics and the quasi-steady-state assumption: Application to the Gillespie algorithm

31 March 2020

1 reference

Accurate hybrid stochastic simulation of a system of coupled chemical or biochemical reactions

31 March 2020

1 reference

Overcoming stiffness in stochastic simulation stemming from partial equilibrium: a multiscale Monte Carlo algorithm.

31 March 2020

1 reference

Nested stochastic simulation algorithm for chemical kinetic systems with disparate rates.

31 March 2020

1 reference

The chemical Langevin equation

31 March 2020

1 reference

Intrinsic and extrinsic contributions to stochasticity in gene expression

31 March 2020

1 reference

Regulatory control and the costs and benefits of biochemical noise

31 March 2020

1 reference

BGX: a fully Bayesian integrated approach to the analysis of Affymetrix GeneChip data

31 March 2020

1 reference

Bayesian modeling of differential gene expression

31 March 2020

1 reference

Inferring cellular networks using probabilistic graphical models

31 March 2020

1 reference

Reconstruction of gene networks using Bayesian learning and manipulation experiments

31 March 2020

1 reference

A Bayesian approach to reconstructing genetic regulatory networks with hidden factors.

31 March 2020

1 reference

An empirical Bayes approach to inferring large-scale gene association networks.

31 March 2020

1 reference

Comparative evaluation of reverse engineering gene regulatory networks with relevance networks, graphical gaussian models and bayesian networks.

31 March 2020

1 reference

Sensitivity and specificity of inferring genetic regulatory interactions from microarray experiments with dynamic Bayesian networks

31 March 2020

1 reference

Advances to Bayesian network inference for generating causal networks from observational biological data

31 March 2020

1 reference

Learning causal networks from systems biology time course data: an effective model selection procedure for the vector autoregressive process

31 March 2020

1 reference

High-throughput fluorescence microscopy for systems biology

31 March 2020

1 reference

Automated tracking of gene expression in individual cells and cell compartments.

31 March 2020

1 reference

Linking data to models: data regression

31 March 2020

1 reference

Parameter estimation in biochemical pathways: a comparison of global optimization methods

31 March 2020

1 reference

Statistical mechanical approaches to models with many poorly known parameters

31 March 2020

1 reference

Ranked prediction of p53 targets using hidden variable dynamic modeling

31 March 2020

1 reference

Bayesian ranking of biochemical system models.

31 March 2020

1 reference

Biochemical networks with uncertain parameters.

31 March 2020

1 reference

Equation of State Calculations by Fast Computing Machines

31 March 2020

1 reference

Monte Carlo sampling methods using Markov chains and their applications

31 March 2020

1 reference

BioBayes: a software package for Bayesian inference in systems biology

31 March 2020

1 reference

Parameter estimation in stochastic biochemical reactions.

31 March 2020

1 reference

Simulated maximum likelihood method for estimating kinetic rates in gene expression.

31 March 2020

1 reference

A stochastic model of gene transcription: an application to L1 retrotransposition events.

31 March 2020

1 reference

Bayesian inference for stochastic kinetic models using a diffusion approximation.

31 March 2020

1 reference

Bayesian inference for dynamic transcriptional regulation; the Hes1 system as a case study.

31 March 2020

1 reference

Bayesian sequential inference for stochastic kinetic biochemical network models.

31 March 2020

1 reference

Bayesian calibration of computer models

31 March 2020

1 reference

On the Theory of the Brownian Motion

31 March 2020

1 reference

A probabilistic model for cell cycle distributions in synchrony experiments.

31 March 2020

1 reference

Global control of cell-cycle transcription by coupled CDK and network oscillators

31 March 2020

1 reference

The Bayesian revolution in genetics

31 March 2020

1 reference

Bayesian methods in bioinformatics and computational systems biology

31 March 2020

1 reference

Molecular level stochastic model for competence cycles in Bacillus subtilis

31 March 2020

1 reference

Stripping Bacillus: ComK auto-stimulation is responsible for the bistable response in competence development

31 March 2020

1 reference

Phosphatases modulate the bistable sporulation gene expression pattern in Bacillus subtilis.

31 March 2020

1 reference

A spatially extended stochastic model of the bacterial chemotaxis signalling pathway

31 March 2020

1 reference

Noise minimization in eukaryotic gene expression

31 March 2020

1 reference

Noise in protein expression scales with natural protein abundance

31 March 2020

1 reference

Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise

31 March 2020

1 reference

Towards an e-biology of ageing: integrating theory and data

31 March 2020

1 reference

Modelling the checkpoint response to telomere uncapping in budding yeast.

31 March 2020

1 reference

Modelling the actions of chaperones and their role in ageing.

31 March 2020

1 reference

Towards a network theory of ageing: a model combining the free radical theory and the protein error theory.

31 March 2020

1 reference

A stochastic model of cell replicative senescence based on telomere shortening, oxidative stress, and somatic mutations in nuclear and mitochondrial DNA

31 March 2020

1 reference

Transient heterogeneity in extracellular protease production by Bacillus subtilis

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19139763

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Stochastic kinetic analysis of developmental pathway bifurcation in phage lambda-infected Escherichia coli cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19139763

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRG2509

1 reference

14 April 2018

1 reference

14 April 2018