(Q34533772)

2 August 2017

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents (English)

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2 August 2017

Caenorhabditis elegans

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14

Johan Auwerx

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Laurent Mouchiroud

2

Laurent Mouchiroud

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Dongryeol Ryu

Dongryeol Ryu

1

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Evan G Williams

Evan G Williams

7

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Pooja Jha

Pooja Jha

8

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Carmen Sandi

Carmen Sandi

12

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author name string

Pénélope A Andreux

3

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2 August 2017

Elena Katsyuba

4

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2 August 2017

Norman Moullan

5

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2 August 2017

Amandine A Nicolet-Dit-Félix

6

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2 August 2017

Giuseppe Lo Sasso

9

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2 August 2017

Damien Huzard

10

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2 August 2017

Patrick Aebischer

11

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2 August 2017

Chris Rinsch

13

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2 August 2017

language of work or name

English

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publication date

11 July 2016

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2 August 2017

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2 August 2017

22

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2 August 2017

879-888

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2 August 2017

8

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https://scigraph.springernature.com/pub.10.1038/nm.4132

2 August 2017

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cites work

Food ellagitannins-occurrence, effects of processing and storage

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Pomegranate as a functional food and nutraceutical source

21 January 2018

1 reference

Strawberry processing does not affect the production and urinary excretion of urolithins, ellagic acid metabolites, in humans.

21 January 2018

1 reference

Occurrence of urolithins, gut microbiota ellagic acid metabolites and proliferation markers expression response in the human prostate gland upon consumption of walnuts and pomegranate juice.

21 January 2018

1 reference

Pomegranate ellagitannin-derived metabolites inhibit prostate cancer growth and localize to the mouse prostate gland

21 January 2018

1 reference

Urolithins, gut microbiota-derived metabolites of ellagitannins, inhibit LPS-induced inflammation in RAW 264.7 murine macrophages

21 January 2018

1 reference

Urolithin A, C, and D, but not iso-urolithin A and urolithin B, attenuate triglyceride accumulation in human cultures of adipocytes and hepatocytes.

21 January 2018

1 reference

21 January 2018

The genetics of ageing

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Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism.

21 January 2018

1 reference

Analysis of aging in Caenorhabditis elegans.

21 January 2018

1 reference

A C. elegans mutant that lives twice as long as wild type

21 January 2018

1 reference

The genetics of caloric restriction in Caenorhabditis elegans

21 January 2018

1 reference

Rates of behavior and aging specified by mitochondrial function during development

21 January 2018

1 reference

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

21 January 2018

1 reference

The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans

21 January 2018

1 reference

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes

21 January 2018

1 reference

Dual roles of autophagy in the survival of Caenorhabditis elegans during starvation

21 January 2018

1 reference

A role for autophagy in the extension of lifespan by dietary restriction in C. elegans

21 January 2018

1 reference

Autophagy genes are essential for dauer development and life-span extension in C. elegans

21 January 2018

1 reference

Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

21 January 2018

1 reference

Fusion and fission: interlinked processes critical for mitochondrial health

21 January 2018

1 reference

Small molecule inhibitors of mitochondrial division: tools that translate basic biological research into medicine

21 January 2018

1 reference

Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa

21 January 2018

1 reference

Eaten alive: a history of macroautophagy

21 January 2018

1 reference

A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications

21 January 2018

1 reference

Methods in mammalian autophagy research

21 January 2018

1 reference

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

21 January 2018

1 reference

Imaging intracellular pH in live cells with a genetically encoded red fluorescent protein sensor.

21 January 2018

1 reference

21 January 2018

Mechanisms of mitophagy

1 reference

Fate of microbial metabolites of dietary polyphenols in rats: is the brain their target destination?

21 January 2018

1 reference

A role for ubiquitin in selective autophagy

21 January 2018

1 reference

Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy

21 January 2018

1 reference

The role of mitochondria in aging

21 January 2018

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21 January 2018

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Pharmacological approaches to restore mitochondrial function

21 January 2018

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Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice

21 January 2018

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Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats

21 January 2018

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Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice

21 January 2018

1 reference

Reversal of hypertriglyceridemia, fatty liver disease, and insulin resistance by a liver-targeted mitochondrial uncoupler

21 January 2018

1 reference

Frailty in older adults: evidence for a phenotype

21 January 2018

1 reference

Downregulation of E3 ubiquitin ligases and mitophagy-related genes in skeletal muscle of physically inactive, frail older women: a cross-sectional comparison.

21 January 2018

1 reference

Nutrition and sarcopenia: a review of the evidence and implications for preventive strategies

21 January 2018

1 reference

Treatment of sporadic inclusion body myositis with bimagrumab

21 January 2018

1 reference

Clinical effectiveness of protein and amino acid supplementation on building muscle mass in elderly people: a meta-analysis

21 January 2018

1 reference

CRIF1 Is Essential for the Synthesis and Insertion of Oxidative Phosphorylation Polypeptides in the Mammalian Mitochondrial Membrane

21 January 2018

1 reference

Architecture of the large subunit of the mammalian mitochondrial ribosome

21 January 2018

1 reference

Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans

21 January 2018

1 reference

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

21 January 2018

1 reference

Mitonuclear protein imbalance as a conserved longevity mechanism

21 January 2018

1 reference

Caenorhabditis elegans as a model system for mtDNA replication defects.

21 January 2018

1 reference

Analysis of Mitochondrial Respiratory Chain Supercomplexes Using Blue Native Polyacrylamide Gel Electrophoresis (BN-PAGE).

21 January 2018

1 reference

Immortalization of mouse intestinal epithelial cells by the SV40-large T gene. Phenotypic and immune characterization of the MODE-K cell line

21 January 2018

1 reference

NCoR1 is a conserved physiological modulator of muscle mass and oxidative function

21 January 2018

1 reference

Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients

21 January 2018

1 reference

Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health Status

21 January 2018

1 reference

Biological significance of urolithins, the gut microbial ellagic Acid-derived metabolites: the evidence so far

21 January 2018

1 reference

12 December 2020

No longer going to waste

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12 December 2020

Pomegranate juice ellagitannin metabolites are present in human plasma and some persist in urine for up to 48 hours

1 reference

12 December 2020

Plant-animal subsistence ratios and macronutrient energy estimations in worldwide hunter-gatherer diets

1 reference

12 December 2020

Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans

1 reference

12 December 2020

Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblasts

1 reference

12 December 2020

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.4132

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Dimensions Publication ID

2 August 2017

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