(Q34536666)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

author name string

Xia Ding

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Arnab Ray Chaudhuri

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Elsa Callen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Yan Pang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Kajal Biswas

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Kimberly D Klarmann

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Betty K Martin

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Sandra Burkett

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Linda Cleveland

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Stacey Stauffer

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Teresa Sullivan

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Aashish Dewan

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Hanna Marks

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Anthony T Tubbs

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Nancy Wong

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Keiko Akagi

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Scott E Martin

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Jonathan R Keller

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

André Nussenzweig

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Shyam K Sharan

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

language of work or name

English

0 references

publication date

8 August 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

page(s)

12425

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

20 March 2020

copyright license

start time

8 August 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4979061/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms12425

0 references

cites work

Replication fork stability confers chemoresistance in BRCA-deficient cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979061

PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining.

7 July 2018

1 reference

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7 July 2018

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Readers of poly(ADP-ribose): designed to be fit for purpose

7 July 2018

1 reference

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Timeless Interacts with PARP-1 to Promote Homologous Recombination Repair

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979061

Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4.

7 July 2018

1 reference

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Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial.

7 July 2018

1 reference

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CtIP-mediated resection is essential for viability and can operate independently of BRCA1.

7 July 2018

1 reference

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Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation

7 July 2018

1 reference

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Genome engineering using the CRISPR-Cas9 system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979061

Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979061

A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.

7 July 2018

1 reference

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Topoisomerase I poisoning results in PARP-mediated replication fork reversal

7 July 2018

1 reference

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Analysis of protein dynamics at active, stalled, and collapsed replication forks.

7 July 2018

1 reference

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Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

7 July 2018

1 reference

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Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells.

7 July 2018

1 reference

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53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

7 July 2018

1 reference

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Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks

7 July 2018

1 reference

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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

7 July 2018

1 reference

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PARP inhibition: PARP1 and beyond

7 July 2018

1 reference

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PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.

7 July 2018

1 reference

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Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

7 July 2018

1 reference

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Linking the cellular functions of BRCA genes to cancer pathogenesis and treatment

7 July 2018

1 reference

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Mouse embryonic stem cell-based functional assay to evaluate mutations in BRCA2

7 July 2018

1 reference

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PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites

7 July 2018

1 reference

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ATM prevents the persistence and propagation of chromosome breaks in lymphocytes

7 July 2018

1 reference

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Loss of Parp-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells

7 July 2018

1 reference

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The concept of synthetic lethality in the context of anticancer therapy

7 July 2018

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

7 July 2018

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Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

7 July 2018

1 reference

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Involvement of poly(ADP-ribose) polymerase in base excision repair

7 July 2018

1 reference

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PARP is important for genomic stability but dispensable in apoptosis

7 July 2018

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Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

7 July 2018

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B lymphocyte-specific, Cre-mediated mutagenesis in mice

7 July 2018

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A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage

7 July 2018

1 reference

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Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4979061

Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS12425

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS12425

Monitoring the spatiotemporal dynamics of proteins at replication forks and in assembled chromatin using isolation of proteins on nascent DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS12425

Mre11-dependent degradation of stalled DNA replication forks is prevented by BRCA2 and PARP1

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27498558

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Laser capture microdissection for protein and NanoString RNA analysis

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS12425

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS12425

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

20 March 2020

ADS bibcode

2016NatCo...712425D

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27498558%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference