(Q39041714)

8 September 2017

title

Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation (English)

1 reference

8 September 2017

13

1 reference

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12 June 2020

Zhongwei Zhou

4

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12 June 2020

Cornelis F Calkhoven

11

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12 June 2020

author name string

WooKee Min

1

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12 June 2020

Christopher Bruhn

2

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12 June 2020

Paulius Grigaravicius

3

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12 June 2020

Fu Li

5

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12 June 2020

Anja Krüger

6

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12 June 2020

Bénazir Siddeek

7

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12 June 2020

Karl-Otto Greulich

8

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12 June 2020

Oliver Popp

9

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12 June 2020

Chris Meisezahl

10

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12 June 2020

Alexander Bürkle

12

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12 June 2020

Zhao-Qi Wang

14

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12 June 2020

language of work or name

English

0 references

publication date

1 January 2013

1 reference

8 September 2017

published in

Nature Communications

1 reference

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12 June 2020

volume

4

1 reference

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12 June 2020

page(s)

2993

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https://scigraph.springernature.com/pub.10.1038/ncomms3993

12 June 2020

exact match

0 references

cites work

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Studying the DNA damage response using in vitro model systems

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Replication protein A-mediated recruitment and activation of Rad17 complexes

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

TopBP1 activates the ATR-ATRIP complex

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

TopBP1 activates ATR through ATRIP and a PIKK regulatory domain

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

New insights into checkpoint kinase 1 in the DNA damage response signaling network

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

ATR: an essential regulator of genome integrity

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

ATR/Mec1: coordinating fork stability and repair.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Chk1 requirement for high global rates of replication fork progression during normal vertebrate S phase

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

The ATR pathway: fine-tuning the fork

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Chk1 promotes replication fork progression by controlling replication initiation

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Poly(ADP-ribose). The most elaborate metabolite of NAD+.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Poly (ADP-ribose) glycohydrolase (PARG) and its therapeutic potential

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Single-strand break repair and genetic disease

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Introduction to poly(ADP-ribose) metabolism

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Poly(ADP-ribose): novel functions for an old molecule

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

ATR signaling mediates an S-phase checkpoint after inhibition of poly(ADP-ribose) polymerase activity.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

APLF (C2orf13) is a novel component of poly(ADP-ribose) signaling in mammalian cells.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Learning how to read ADP-ribosylation

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Inhibition of DNA synthesis by ionizing radiation: a marker for an S-phase checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Activation of mammalian Chk1 during DNA replication arrest: a role for Chk1 in the intra-S phase checkpoint monitoring replication origin firing

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Cdk-mediated phosphorylation of Chk1 is required for efficient activation and full checkpoint proficiency in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Monitoring the spatiotemporal dynamics of proteins at replication forks and in assembled chromatin using isolation of proteins on nascent DNA.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Poly(ADP-ribose) binding properties of histone H1 variants

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Poly(ADP-ribose) effectively competes with DNA for histone H4 binding

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Quantitative analysis of the binding affinity of poly(ADP-ribose) to specific binding proteins as a function of chain length

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

https://api.crossref.org/works/10.1038%2FNCOMMS3993

1 reference

7 January 2021

Chk1 C-terminal regulatory phosphorylation mediates checkpoint activation by de-repression of Chk1 catalytic activity.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

PARP inhibition: PARP1 and beyond

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Targeting the S and G2 checkpoint to treat cancer.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Anticancer therapy with checkpoint inhibitors: what, where and when?

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA.

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

PARP is important for genomic stability but dispensable in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1-Cdc25 pathway

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

High resolution fractionation and characterization of ADP-ribose polymers

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Poly(ADP-ribose) quantification at the femtomole level in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Characterization of polymers of adenosine diphosphate ribose generated in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Chk2 activation and phosphorylation-dependent oligomerization

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS3993

7 January 2021

Identifiers

DOI

10.1038/NCOMMS3993

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24356582%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 June 2020

ADS bibcode

2013NatCo...4.2993M

0 references

1014680261

0 references

Fatcat ID

release_w2rhor644jabrfhqxvskz5e2ka

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/w2rhor644jabrfhqxvskz5e2ka

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24356582%20AND%20SRC:MED&resulttype=core&format=json