(Q34538158)

2 August 2017

A transmembrane leucine zipper is required for activation of the dimeric receptor tyrosine kinase DDR1. (English)

1 reference

2 August 2017

transmembrane protein

0 references

5

Birgit Leitinger

1 reference

2 August 2017

3

Erhard Hohenester

1 reference

2 August 2017

2

Federico Carafoli

1 reference

2 August 2017

Nafeesa A Noordeen

1

1 reference

PubMed ID

16774916

2 August 2017

Michael A Horton

series ordinal

4

1 reference

PubMed ID

16774916

2 August 2017

language of work or name

English

0 references

publication date

14 June 2006

1 reference

Journal of Biological Chemistry

2 August 2017

1 reference

2 August 2017

281

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2 August 2017

22744-22751

1 reference

2 August 2017

32

1 reference

Cell signaling by receptor tyrosine kinases

2 August 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Ligand-independent dimer formation of epidermal growth factor receptor (EGFR) is a step separable from ligand-induced EGFR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Preformed oligomeric epidermal growth factor receptors undergo an ectodomain structure change during signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

The discoidin domain receptor tyrosine kinases are activated by collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

The D2 period of collagen II contains a specific binding site for the human discoidin domain receptor, DDR2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Discoidin domain receptor 1 tyrosine kinase has an essential role in mammary gland development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

The discoidin domain receptor tyrosine kinase DDR1 in arterial wound repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling: potential implications in atherosclerosis and lymphangioleiomyomatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Overexpression of the cell adhesion molecules DDR1, Claudin 3, and Ep-CAM in metaplastic ovarian epithelium and ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

p53 induction and activation of DDR1 kinase counteract p53-mediated apoptosis and influence p53 regulation through a positive feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Identification of genes associated with the invasive status of human mammary carcinoma cell lines by transcriptional profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Discoidin domain receptor 2 mediates tumor cell cycle arrest induced by fibrillar collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Discoidin domain receptor-1a (DDR1a) promotes glioma cell invasion and adhesion in association with matrix metalloproteinase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Activation of discoidin domain receptor 1 on CD14-positive bronchoalveolar lavage fluid cells induces chemokine production in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Molecular analysis of collagen binding by the human discoidin domain receptors, DDR1 and DDR2. Identification of collagen binding sites in DDR2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

TOXCAT: a measure of transmembrane helix association in a biological membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Mapping of epitopes in discoidin domain receptor 1 critical for collagen binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

A sequence motif in the transmembrane region of growth factor receptors with tyrosine kinase activity mediates dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

The GxxxG motif: a framework for transmembrane helix-helix association

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

A transmembrane helix dimer: structure and implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

The single transmembrane domains of ErbB receptors self-associate in cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

In vitro selection of membrane-spanning leucine zipper protein-protein interaction motifs using POSSYCCAT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Coiled coil domains: stability, specificity, and biological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Self assembly of the transmembrane domain promotes signal transduction through the erythropoietin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Ligand-induced shedding of discoidin domain receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Oligomerization of epidermal growth factor receptors on A431 cells studied by time-resolved fluorescence imaging microscopy. A stereochemical model for tyrosine kinase receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Mechanism of transmembrane signaling: insulin binding and the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Ligand-independent growth hormone receptor dimerization occurs in the endoplasmic reticulum and is required for ubiquitin system-dependent endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Model for growth hormone receptor activation based on subunit rotation within a receptor dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Two motifs within a transmembrane domain, one for homodimerization and the other for heterodimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

The interface between self-assembling erythropoietin receptor transmembrane segments corresponds to a membrane-spanning leucine zipper

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603233200

21 January 2018

Identifiers

DOI

10.1074/JBC.M603233200

1 reference

2 August 2017

1 reference

PubMed ID

16774916