(Q34540424)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23300602%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

A natural small molecule harmine inhibits angiogenesis and suppresses tumour growth through activation of p53 in endothelial cells (English)

1 reference

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21 February 2020

0 references

1 reference

2

1 reference

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21 February 2020

Mingyao Liu

11

1 reference

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21 February 2020

author name string

Fujun Dai

1

1 reference

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21 February 2020

Yajuan Song

3

1 reference

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21 February 2020

Li Huang

4

1 reference

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21 February 2020

Dong Zhai

5

1 reference

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21 February 2020

Yanmin Dong

6

1 reference

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21 February 2020

Li Lai

7

1 reference

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21 February 2020

Tao Zhang

8

1 reference

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21 February 2020

Dali Li

9

1 reference

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21 February 2020

Xiufeng Pang

10

1 reference

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21 February 2020

Zhengfang Yi

12

1 reference

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21 February 2020

language of work or name

English

0 references

publication date

27 December 2012

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21 February 2020

1 reference

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21 February 2020

volume

7

1 reference

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21 February 2020

issue

12

1 reference

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21 February 2020

page(s)

e52162

1 reference

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Creative Commons Attribution 4.0 International

21 February 2020

copyright license

start time

27 December 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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A small molecule Inauhzin inhibits SIRT1 activity and suppresses tumour growth through activation of p53.

7 July 2018

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Harmine induces apoptosis in HepG2 cells via mitochondrial signaling pathway.

7 July 2018

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Plumbagin inhibits tumour angiogenesis and tumour growth through the Ras signalling pathway following activation of the VEGF receptor-2

7 July 2018

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β-carboline compounds, including harmine, inhibit DYRK1A and tau phosphorylation at multiple Alzheimer's disease-related sites

7 July 2018

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Activation of p53 by nutlin-3a induces apoptosis and cellular senescence in human glioblastoma multiforme

7 July 2018

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Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2-mediated JAK/STAT3 signaling in endothelial cell.

7 July 2018

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Harmine inhibits tumour specific neo-vessel formation by regulating VEGF, MMP, TIMP and pro-inflammatory mediators both in vivo and in vitro

7 July 2018

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Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway.

7 July 2018

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Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis

7 July 2018

1 reference

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Structure-based Design of High Affinity Peptides Inhibiting the Interaction of p53 with MDM2 and MDMX

7 July 2018

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Kisspeptin-10, a KISS1-derived decapeptide, inhibits tumor angiogenesis by suppressing Sp1-mediated VEGF expression and FAK/Rho GTPase activation

7 July 2018

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Efficient activation of p53 pathway in A549 cells exposed to L2, a novel compound targeting p53-MDM2 interaction

7 July 2018

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Restoration of p53 pathway by nutlin-3 induces cell cycle arrest and apoptosis in human rhabdomyosarcoma cells

7 July 2018

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7 July 2018

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A novel peptide from human apolipoprotein(a) inhibits angiogenesis and tumor growth by targeting c-Src phosphorylation in VEGF-induced human umbilical endothelial cells

7 July 2018

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Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

7 July 2018

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A complex barcode underlies the heterogeneous response of p53 to stress

7 July 2018

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15-deoxy-Delta(12,14)-prostaglandin J2 induces vascular endothelial cell apoptosis through the sequential activation of MAPKS and p53.

7 July 2018

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7 July 2018

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7 July 2018

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Survivin repression by p53, Rb and E2F2 in normal human melanocytes

7 July 2018

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7 July 2018

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Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: binding to MDM2, stabilization of p53 protein, and activation of p53 function

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

1 reference

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7 July 2018

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7 July 2018

1 reference

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Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3

7 July 2018

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K-Ras-independent effects of the farnesyl transferase inhibitor L-744,832 on cyclin B1/Cdc2 kinase activity, G2/M cell cycle progression and apoptosis in human pancreatic ductal adenocarcinoma cells

7 July 2018

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

7 July 2018

1 reference

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Cooperative phosphorylation at multiple sites is required to activate p53 in response to UV radiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531399

Antiviral effect of harmine, a photoactive beta-carboline alkaloid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531399

Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531399

Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways.

7 July 2018

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Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation

21 January 2018

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The anti-angiogenic effect of sinomenine

21 January 2018

1 reference

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Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

21 January 2018

1 reference

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Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

21 January 2018

1 reference

12 December 2020

Relationship between VEGF and p53 expression and tumor cell proliferation in human gastrointestinal carcinomas

1 reference

12 December 2020

Exploring "one-shot" kinetics and small molecule analysis using the ProteOn XPR36 array biosensor

1 reference

12 December 2020

Functional interactions of p53 with poly(ADP-ribose) polymerase (PARP) during apoptosis following DNA damage: covalent poly(ADP-ribosyl)ation of p53 by exogenous PARP and noncovalent binding of p53 to the M(r) 85,000 proteolytic fragment

1 reference

12 December 2020

The comet assay: a method to measure DNA damage in individual cells

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0052162

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23300602%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23300602%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23300602%20AND%20SRC:MED&resulttype=core&format=json