(Q34540964)

2 August 2017

title

Global DNA hypomethylation prevents consolidation of differentiation programs and allows reversion to the embryonic stem cell state (English)

1 reference

2 August 2017

Fabio Spada

10

0 references

author name string

Christine S Schmidt

1

1 reference

2 August 2017

Sebastian Bultmann

2

1 reference

2 August 2017

Daniela Meilinger

3

1 reference

2 August 2017

Benedikt Zacher

4

1 reference

2 August 2017

Achim Tresch

5

1 reference

2 August 2017

Kerstin C Maier

6

1 reference

2 August 2017

Christian Peter

7

1 reference

2 August 2017

Dietmar E Martin

8

1 reference

2 August 2017

Heinrich Leonhardt

9

1 reference

2 August 2017

language of work or name

English

0 references

publication date

27 December 2012

1 reference

2 August 2017

1 reference

2 August 2017

volume

7

1 reference

2 August 2017

issue

12

1 reference

2 August 2017

page(s)

e52629

1 reference

Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

27 December 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3531338

based on heuristic

inferred from PubMed Central ID database lookup

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Inactivation of Dnmt3b in mouse embryonic fibroblasts results in DNA hypomethylation, chromosomal instability, and spontaneous immortalization.

7 July 2018

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Replication-independent chromatin loading of Dnmt1 during G2 and M phases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

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7 July 2018

1 reference

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Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

7 July 2018

1 reference

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Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b.

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

7 July 2018

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The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

7 July 2018

1 reference

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Multipotent cell lineages in early mouse development depend on SOX2 function

7 July 2018

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MethPrimer: designing primers for methylation PCRs

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

Comprehensive analysis of CpG islands in human chromosomes 21 and 22

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

DNA methylation patterns and epigenetic memory

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

7 July 2018

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Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

DNA hypomethylation can activate Xist expression and silence X-linked genes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3531338

A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

7 July 2018

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7 July 2018

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Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells

21 January 2018

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Dnmt3L and the establishment of maternal genomic imprints

21 January 2018

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Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5.

21 January 2018

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DNA methylation is dispensable for the growth and survival of the extraembryonic lineages.

21 January 2018

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DNA methylation represses transcription in vivo.

21 January 2018

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Stage- and cell-specific expression of Dnmt3a and Dnmt3b during embryogenesis.

21 January 2018

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Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation

21 January 2018

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Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors.

21 January 2018

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The orphan nuclear receptor GCNF recruits DNA methyltransferase for Oct-3/4 silencing

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23300728

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0052629

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference