(Q34541179)

2 August 2017

title

Conserved acidic amino acid residues in a second RNA recognition motif regulate assembly and function of TDP-43. (English)

1 reference

RNA recognition motif domain

2 August 2017

main subject

1 reference

Makoto Urushitani

10

0 references

author name string

Akemi Shodai

1

1 reference

2 August 2017

Akemi Ido

2

1 reference

2 August 2017

Noriko Fujiwara

3

1 reference

2 August 2017

Takashi Ayaki

4

1 reference

2 August 2017

Toshifumi Morimura

5

1 reference

2 August 2017

Miki Oono

6

1 reference

2 August 2017

Tsukasa Uchida

7

1 reference

2 August 2017

Ryosuke Takahashi

8

1 reference

2 August 2017

Hidefumi Ito

9

1 reference

2 August 2017

language of work or name

English

0 references

publication date

26 December 2012

1 reference

2 August 2017

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2 August 2017

volume

7

1 reference

2 August 2017

issue

12

1 reference

2 August 2017

page(s)

e52776

1 reference

Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

26 December 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.

7 July 2018

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Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion

7 July 2018

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Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

7 July 2018

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A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions

7 July 2018

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TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling

7 July 2018

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The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism

7 July 2018

1 reference

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Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA.

7 July 2018

1 reference

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Neurotoxic effects of TDP-43 overexpression in C. elegans

7 July 2018

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Mutations of optineurin in amyotrophic lateral sclerosis

7 July 2018

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Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP-43.

7 July 2018

1 reference

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Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43.

7 July 2018

1 reference

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Structural insights into TDP-43 in nucleic-acid binding and domain interactions

7 July 2018

1 reference

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Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis

7 July 2018

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A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

7 July 2018

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TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

7 July 2018

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TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

7 July 2018

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Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation

7 July 2018

1 reference

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Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43.

7 July 2018

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TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions

7 July 2018

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TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

7 July 2018

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7 July 2018

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Structural basis of protein kinetic stability: resistance to sodium dodecyl sulfate suggests a central role for rigidity and a bias toward beta-sheet structure.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3530536

Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3530536

TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation

7 July 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052776

TDP-43 mutation in familial amyotrophic lateral sclerosis

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052776

Delineation of the core aggregation sequences of TDP-43 C-terminal fragment

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052776

An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052776

TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052776

Axonal ligation induces transient redistribution of TDP-43 in brainstem motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0052776

Novel method for evaluation of the oligomeric structure of membrane proteins

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3530536

Aggregation of the 35-kDa fragment of TDP-43 causes formation of cytoplasmic inclusions and alteration of RNA processing

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23300771

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0052776

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference