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Overexpression of Mcl-1L splice variant is associated with poor prognosis and chemoresistance in oral cancers
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scholarly article
1 reference
stated in
Q5412157
PubMed ID
25409302
retrieved
2 August 2017
title
Overexpression of Mcl-1L splice variant is associated with poor prognosis and chemoresistance in oral cancers
(English)
1 reference
stated in
Q5412157
PubMed ID
25409302
retrieved
2 August 2017
main subject
overexpression
1 reference
based on heuristic
inferred from title
lip and oral cavity carcinoma
1 reference
based on heuristic
inferred from title
author
Vinayak C Palve
object named as
Vinayak Palve
series ordinal
1
0 references
Sadhana Kannan
series ordinal
4
object named as
Sadhana Kannan
1 reference
stated in
Q5412157
PubMed ID
25409302
retrieved
2 August 2017
author name string
Sanchita Mallick
series ordinal
2
1 reference
stated in
Q5412157
PubMed ID
25409302
retrieved
2 August 2017
Gauri Ghaisas
series ordinal
3
1 reference
stated in
Q5412157
PubMed ID
25409302
retrieved
2 August 2017
Tanuja Teni
series ordinal
5
1 reference
stated in
Q5412157
PubMed ID
25409302
retrieved
2 August 2017
language of work or name
English
0 references
publication date
19 November 2014
1 reference
stated in
Q5412157
PubMed ID
25409302
retrieved
2 August 2017
published in
PLOS One
1 reference
stated in
Q5412157
PubMed ID
25409302
retrieved
2 August 2017
volume
9
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stated in
Q5412157
PubMed ID
25409302
retrieved
2 August 2017
page(s)
e111927
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Q5412157
PubMed ID
25409302
retrieved
2 August 2017
issue
11
1 reference
stated in
Q5412157
PubMed ID
25409302
retrieved
2 August 2017
copyright license
Creative Commons Attribution 4.0 International
start time
19 November 2014
1 reference
stated in
April 2022 Public Data File from Crossref
copyright status
copyrighted
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describes a project that uses
ImageJ
1 reference
stated in
Q5412157
retrieved
11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4237324/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
Single-agent obatoclax (GX15-070) potently induces apoptosis and pro-survival autophagy in head and neck squamous cell carcinoma cells
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7 July 2018
The pan-Bcl-2 blocker obatoclax promotes the expression of Puma, Noxa, and Bim mRNA and induces apoptosis in neoplastic mast cells
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7 July 2018
Challenges of the oral cancer burden in India
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7 July 2018
Association of anti-apoptotic Mcl-1L isoform expression with radioresistance of oral squamous carcinoma cells
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PubMed Central
reference URL
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7 July 2018
Targeting Mcl-1 for the therapy of cancer
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PubMed Central
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7 July 2018
Nuclear localization of Nm23-H1 in head and neck squamous cell carcinoma is associated with radiation resistance
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7 July 2018
Mcl-1 is critical for survival in a subgroup of non-small-cell lung cancer cell lines
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7 July 2018
Up-regulation of survivin in oral squamous cell carcinoma correlates with poor prognosis and chemoresistance
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
PCNA and anti-apoptotic Mcl-1 proteins predict disease-free survival in oral cancer patients treated with definitive radiotherapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Mcl-1; the molecular regulation of protein function
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Mcl-1 is an important determinant of the apoptotic response to the BH3-mimetic molecule HA14-1 in cisplatin-resistant ovarian carcinoma cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
MCL-1ES, a novel variant of MCL-1, associates with MCL-1L and induces mitochondrial cell death
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Prognostic role of myeloid cell leukemia-1 protein (Mcl-1) expression in human gastric cancer
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Role of myeloid cell leukemia-1 in cell growth of squamous cell carcinoma
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Mcl1 downregulation sensitizes neuroblastoma to cytotoxic chemotherapy and small molecule Bcl2-family antagonists.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Mcl-1 is a potential therapeutic target in multiple types of cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Human oral cancers have altered expression of Bcl-2 family members and increased expression of the anti-apoptotic splice variant of Mcl-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Analyzing real-time PCR data by the comparative C(T) method
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Down-regulation of mcl-1 by small interfering RNA sensitizes resistant melanoma cells to fas-mediated apoptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Suppression of Mcl-1 via RNA interference sensitizes human hepatocellular carcinoma cells towards apoptosis induction.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Mcl-1 overexpression in hepatocellular carcinoma: a potential target for antisense therapy
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Implications of cytokeratin 8/18 filament formation in stratified epithelial cells: induction of transformed phenotype
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Expression and prognostic relevance of Mcl-1 in breast cancer.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
The Bcl2 family: regulators of the cellular life-or-death switch
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Dysregulation of apoptosis in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
Establishment and characterization of four new squamous cell carcinoma cell lines derived from oral tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
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7 July 2018
DOK, a cell line established from human dysplastic oral mucosa, shows a partially transformed non-malignant phenotype
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
retrieved
7 July 2018
Cancer mortality in India: a nationally representative survey.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0111927
retrieved
21 January 2018
Mcl-1 is downregulated in cisplatin-induced apoptosis, and proteasome inhibitors restore Mcl-1 and promote survival in renal tubular epithelial cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0111927
retrieved
21 January 2018
Expression of Mcl-1 splicing variants in clear-cell renal cancer and their correlation with histopathological parameters and prognosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0111927
retrieved
21 January 2018
MiR-101 and Mcl-1 in non-small-cell lung cancer: expression profile and clinical significance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0111927
retrieved
21 January 2018
The expression of Mcl-1 in human cervical cancer and its clinical significance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0111927
retrieved
21 January 2018
Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0111927
retrieved
21 January 2018
Increased MCL-1 expression is associated with poor prognosis in ovarian carcinomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237324
retrieved
27 October 2018
Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25409302
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1371/JOURNAL.PONE.0111927
1 reference
stated in
Q5412157
PubMed ID
25409302
retrieved
2 August 2017
ADS bibcode
2014PLoSO...9k1927P
0 references
PMCID
4237324
1 reference
stated in
Q5412157
PubMed ID
25409302
retrieved
2 August 2017
PubMed ID
25409302
1 reference
stated in
Q5412157
PubMed ID
25409302
retrieved
2 August 2017
ResearchGate publication ID
268791205
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