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On the brink of becoming a T cell.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
On the brink of becoming a T cell
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
author
Fabio Grassi
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
Iannis Aifantis
series ordinal
5
object named as
Iannis Aifantis
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
Harald von Boehmer
series ordinal
7
object named as
Harald von Boehmer
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
author name string
Christine Borowski
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
Colin Martin
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
Fotini Gounari
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
Loralee Haughn
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
publication date
1 April 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
published in
Current Opinion in Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
volume
14
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
page(s)
200-206
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
cites work
Purification and characterization of mouse hematopoietic stem cells
1 reference
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reference URL
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7 January 2021
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The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype
1 reference
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7 January 2021
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7 January 2021
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Identification of clonogenic common lymphoid progenitors in mouse bone marrow
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reference URL
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7 January 2021
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CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mouse thymus dendritic cells: kinetics of development and changes in surface markers during maturation
1 reference
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reference URL
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7 January 2021
based on heuristic
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Early T lymphocyte progenitors
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Frequency analysis of the T cell precursors in the thymus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bipotential precursors of B cells and macrophages in murine fetal liver
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lymphoid precursors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Direct evidence for the commitment of hematopoietic stem cells to T, B and myeloid lineages in murine fetal liver.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
T cell progenitors emerge earlier than B cell progenitors in the murine fetal liver.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Deficient T cell fate specification in mice with an induced inactivation of Notch1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch1 expression in early lymphopoiesis influences B versus T lineage determination.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Notch activity influences the alphabeta versus gammadelta T cell lineage decision
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pleiotropic changes controlled by the pre-T-cell receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Different initiation of pre-TCR and gammadeltaTCR signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymocyte development in the absence of pre-T cell receptor extracellular immunoglobulin domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An endoplasmic reticulum retention function for the cytoplasmic tail of the human pre-T cell receptor (TCR) alpha chain: potential role in the regulation of cell surface pre-TCR expression levels
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The biological activity of natural and mutant pTalpha alleles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic structure of the human pre-T cell receptor alpha chain and expression of two mRNA isoforms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential developmental regulation and functional effects on pre-TCR surface expression of human pTalpha(a) and pTalpha(b) spliced isoforms.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pre-T cell receptor (TCR) and TCR-controlled checkpoints in T cell differentiation are set by Ikaros
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early thymocyte development is regulated by modulation of E2A protein activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The upstream enhancer is necessary and sufficient for the expression of the pre-T cell receptor alpha gene in immature T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2A and HEB activate the pre-TCR alpha promoter during immature T cell development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
On the role of the pre-T cell receptor in alphabeta versus gammadelta T lineage commitment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence that gammadelta versus alphabeta T cell fate determination is initiated independently of T cell receptor signaling.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role of the pre-T cell receptor in allelic exclusion of the T cell receptor beta locus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crucial function of the pre-T-cell receptor (TCR) in TCR beta selection, TCR beta allelic exclusion and alpha beta versus gamma delta lineage commitment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allelic exclusion of the T cell receptor beta locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allelic exclusion and differentiation by protein kinase C-mediated signals in immature thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exclusion and inclusion of α and β T cell receptor alleles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in κ transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of two T cell receptor α chains on the surface of normal murine T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The joining of germ-line V alpha to J alpha genes replaces the preexisting V alpha-J alpha complexes in a T cell receptor alpha, beta positive T cell line.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tight interallelic positional coincidence that distinguishes T-cell receptor Jalpha usage does not result from homologous chromosomal pairing during ValphaJalpha rearrangement
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymocyte Expression of RAG-1 and RAG-2: Termination by T Cell Receptor Cross-Linking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor editing in developing T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
New perspectives on a developmental dilemma: the kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lck activity controls CD4/CD8 T cell lineage commitment.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inducible Expression of a p56Lck Transgene Reveals a Central Role for Lck in the Differentiation of CD4 SP Thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion of the CD4 silencer element supports a stochastic mechanism of thymocyte lineage commitment.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A human CD4 transgene rescues CD4-CD8+ cells in beta 2-microglobulin-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive CD8 expression allows inefficient maturation of CD4+ helper T cells in class II major histocompatibility complex mutant mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900322-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0952-7915(02)00322-9
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
PubMed ID
11869893
1 reference
stated in
Europe PubMed Central
PubMed ID
11869893
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869893%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
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