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Allelic exclusion at the TCRbeta locus.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11869897
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869897%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Allelic exclusion at the TCRbeta locus
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11869897
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869897%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
author
Bernard Khor
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11869897
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869897%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
author name string
Barry P Sleckman
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11869897
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869897%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
publication date
1 April 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
11869897
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869897%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
published in
Current Opinion in Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
11869897
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869897%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
volume
14
1 reference
stated in
Europe PubMed Central
PubMed ID
11869897
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869897%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11869897
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869897%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
page(s)
230-234
1 reference
stated in
Europe PubMed Central
PubMed ID
11869897
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869897%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
cites work
Differential activity of allelic gamma-globulin genes in antibody-producing cells
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reference URL
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7 January 2021
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Cellular localization of immunoglobulins with different allotypic specificities in rabbit lymphoid tissues
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7 January 2021
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Clonal selection and learning in the antibody system
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
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7 January 2021
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Regulation of TCR alpha and beta gene allelic exclusion during T-cell development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
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inferred from DOI database lookup
Exclusion and inclusion of α and β T cell receptor alleles
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
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7 January 2021
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T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
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7 January 2021
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Expression of two T cell receptor alpha chains: dual receptor T cells
1 reference
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Crossref
reference URL
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7 January 2021
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Allelic exclusion of the T cell receptor alpha-chain: developmental regulation of a post-translational event
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Allelic inclusion of T cell receptor alpha genes poses an autoimmune hazard due to low-level expression of autospecific receptors.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
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7 January 2021
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Somatic generation of antibody diversity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
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7 January 2021
based on heuristic
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The RAG proteins and V(D)J recombination: complexes, ends, and transposition
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
V(D)J recombination and double-strand break repair
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
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7 January 2021
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Factors and forces controlling V(D)J recombination
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
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7 January 2021
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V(D)J recombination becomes accessible
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative genomics of the human and mouse T cell receptor loci
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A transcriptional enhancer 3' of C beta 2 in the T cell receptor beta locus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of V(D)J recombinational accessibility of the D beta 1 gene segment at the TCR beta locus by a germline promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of V(D)J recombination by transcriptional promoters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromatin remodeling by the T cell receptor (TCR)-beta gene enhancer during early T cell development: Implications for the control of TCR-beta locus recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and function of the pre-T cell receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Different initiation of pre-TCR and gammadeltaTCR signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymocyte development in the absence of pre-T cell receptor extracellular immunoglobulin domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptors and signals in early thymic selection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The roles of preB and B cell receptors in the stepwise allelic exclusion of mouse IgH and L chain gene loci
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allelic exclusion in B and T lymphopoiesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In transgenic mice the introduced functional T cell receptor beta gene prevents expression of endogenous beta genes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exit of the pre-TCR from the ER/cis-Golgi is necessary for signaling differentiation, proliferation, and allelic exclusion in immature thymocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CD3-gammadeltaepsilon and CD3-zeta/eta modules are each essential for allelic exclusion at the T cell receptor beta locus but are both dispensable for the initiation of V to (D)J recombination at the T cell receptor-beta, -gamma, and -delta loci
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role of the pre-T cell receptor in allelic exclusion of the T cell receptor beta locus.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein tyrosine kinase p56 lck controls allelic exclusion of T-cell receptor β-chain genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allelic exclusion of the T cell receptor beta locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allelic exclusion and differentiation by protein kinase C-mediated signals in immature thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct signals mediate maturation and allelic exclusion in lymphocyte progenitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activated Ras signals differentiation and expansion of CD4+8+ thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Assembly of productive T cell receptor delta variable region genes exhibits allelic inclusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Asynchronous replication and allelic exclusion in the immune system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kappa chain monoallelic demethylation and the establishment of allelic exclusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and Function in the Nucleus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two waves of recombinase gene expression in developing thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Vbeta germline transcription in RAG-deficient mice by the CD3epsilon-mediated signals: implication of Vbeta transcriptional regulation in TCR beta allelic exclusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A change in the structure of Vbeta chromatin associated with TCR beta allelic exclusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900326-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0952-7915(02)00326-6
1 reference
stated in
Europe PubMed Central
PubMed ID
11869897
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869897%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
PubMed ID
11869897
1 reference
stated in
Europe PubMed Central
PubMed ID
11869897
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11869897%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
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