(Q36381026)

English

The CD3-gammadeltaepsilon and CD3-zeta/eta modules are each essential for allelic exclusion at the T cell receptor beta locus but are both dispensable for the initiation of V to (D)J recombination at the T cell receptor-beta, -gamma, and -delta loci

scientific article

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

The CD3-gammadeltaepsilon and CD3-zeta/eta modules are each essential for allelic exclusion at the T cell receptor beta locus but are both dispensable for the initiation of V to (D)J recombination at the T cell receptor-beta, -gamma, and -delta loci (English)

1 reference

Europe PubMed Central

13 August 2017

object named as

M Malissen

4

0 references

Bernard Malissen

object named as

B Malissen

3

0 references

author name string

L Ardouin

1

1 reference

Europe PubMed Central

13 August 2017

J Ismaili

2

1 reference

Europe PubMed Central

13 August 2017

language of work or name

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publication date

1 January 1998

1 reference

Europe PubMed Central

13 August 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

13 August 2017

187

1 reference

Europe PubMed Central

13 August 2017

1

1 reference

Europe PubMed Central

13 August 2017

105-116

1 reference

Europe PubMed Central

13 August 2017

Allelic exclusion in pTalpha-deficient mice: no evidence for cell surface expression of two T cell receptor (TCR)-beta chains, but less efficient inhibition of endogeneous Vbeta--> (D)Jbeta rearrangements in the presence of a functional TCR-beta tra

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

T cell receptor (TCR)-beta gene recombination: dissociation from cell cycle regulation and developmental progression during T cell ontogeny

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Role of different T cell receptors in the development of pre-T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

CD3 delta deficiency arrests development of the alpha beta but not the gamma delta T cell lineage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Changes in locus-specific V(D)J recombinase activity induced by immunoglobulin gene products during B cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Early T-cell development in CD3-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Functions of TCR and pre-TCR subunits: lessons from gene ablation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Surrogate light chain in B cell development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Function of the pre-T-cell receptor alpha chain in T-cell development and allelic exclusion at the T-cell receptor beta locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

T cell development in mice lacking the CD3-zeta/eta gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Cell cycle regulation of V(D)J recombination-activating protein RAG-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Analysis and expression of a cloned pre-T cell receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

T cell receptor gene recombination patterns and mechanisms: cell death, rescue, and T cell production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Normal T lymphocytes can express two different T cell receptor beta chains: implications for the mechanism of allelic exclusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Dual T cell receptor beta chain expression on human T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

The molecular chaperone calnexin is expressed on the surface of immature thymocytes in association with clonotype-independent CD3 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

T cell tolerance to Mlsa encoded antigens in T cell receptor V beta 8.1 chain transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Profound block in thymocyte development in mice lacking p56lck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Inhibition of T-cell receptor beta-chain gene rearrangement by overexpression of the non-receptor protein tyrosine kinase p56lck

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Engagement of the T-cell receptor during positive selection in the thymus down-regulates RAG-1 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Regulation of TCR alpha and beta gene allelic exclusion during T-cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Early alpha beta T cell development in the thymus of normal and genetically altered mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Control of immunoglobulin gene rearrangements in developing B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

30 September 2017

Restoration of thymopoiesis in pT alpha-/- mice by anti-CD3epsilon antibody treatment or with transgenes encoding activated Lck or tailless pT alpha.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

28 June 2018

TCR zeta chain in T cell development and selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

28 June 2018

alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

28 June 2018

Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

28 June 2018

T cell receptor beta chain dimers on immature thymocytes from normal mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

28 June 2018

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

28 June 2018

Over-expression of CD3 epsilon transgenes blocks T lymphocyte development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

28 June 2018

In transgenic mice the introduced functional T cell receptor beta gene prevents expression of endogenous beta genes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

28 June 2018

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

28 June 2018

T cell receptor delta gene rearrangement and T early alpha (TEA) expression in immature alpha beta lineage thymocytes: implications for alpha beta/gamma delta lineage commitment.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

CD3 epsilon and CD3 zeta cytoplasmic domains can independently generate signals for T cell development and function.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

Regulation of thymocyte development through CD3: functional dissociation between p56lck and CD3 sigma in early thymic selection.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

Regulation of an early developmental checkpoint in the B cell pathway by Ig beta.

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199187

21 October 2018

Double-negative thymocyte subsets in CD3′ chain-deficient mice: Absence of HSA+CD44−CD25− cells

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

T lymphocyte development in p56lck deficient mice: allelic exclusion of the TcR β locus is incomplete but thymocyte development is not restored by TcR β or TcR αβ transgenes

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

T cell receptor δ gene mutant mice: Independent generation of αβ T cells and programmed rearrangements of γδ TCR genes

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

CD3 components at the surface of pro-T cells can mediate pre-T cell developmentin vivo

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

Pro-Thymocyte Expansion by c-kit and the Common Cytokine Receptor γ Chain Is Essential for Repertoire Formation

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

Fyn can partially substitute for Lck in T lymphocyte development

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

Gamma delta T cells promote CD4 and CD8 expression by SCID thymocytes

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

IL-7 transgenic mice: analysis of the role of IL-7 in the differentiation of thymocytes in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

Protein tyrosine kinase p56 lck controls allelic exclusion of T-cell receptor β-chain genes

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

Tracing interactions of thymocytes with individual stromal cell partners

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.1.105

21 January 2018

Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8- thymocyte differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9419216

12 December 2020

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10.1084/JEM.187.1.105

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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