(Q34552674)

3 August 2017

1 reference

title

Glycogen synthase kinase 3: an emerging therapeutic target (English)

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3 August 2017

Hagit Eldar-Finkelman

series ordinal

1

object named as

Hagit Eldar-Finkelman

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3 August 2017

1 March 2002

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Trends in Molecular Medicine

3 August 2017

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3 August 2017

8

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3 August 2017

126-132

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3 August 2017

3

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The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

3 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

GSK3 takes centre stage more than 20 years after its discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

The role of glucose 6-phosphate in the control of glycogen synthase

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Expression and characterization of glycogen synthase kinase-3 mutants and their effect on glycogen synthase activity in intact cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Transient increases in intracellular calcium result in prolonged site-selective increases in Tau phosphorylation through a glycogen synthase kinase 3beta-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Glycogen synthase kinase 3beta is tyrosine phosphorylated by PYK2.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

The novel tyrosine kinase ZAK1 activates GSK3 to direct cell fate specification.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Structure of GSK3beta reveals a primed phosphorylation mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

In vivo regulation of muscle glycogen synthase and the control of glycogen synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Glycogen synthase kinase 3 is an insulin-regulated C/EBPalpha kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

PPAR gamma and the molecular control of adipogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Role of IRS-1-GRB-2 complexes in insulin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Piecing together Alzheimer's.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Phosphorylation of tau by glycogen synthase kinase 3beta in intact mammalian cells influences the stability of microtubules

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Distribution of active glycogen synthase kinase 3beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Preferential labeling of Alzheimer neurofibrillary tangles with antisera for tau protein kinase (TPK) I/glycogen synthase kinase-3 beta and cyclin-dependent kinase 5, a component of TPK II.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Glycogen synthase kinase-3beta phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Amyloid beta peptide induces cytoplasmic accumulation of amyloid protein precursor via tau protein kinase I/glycogen synthase kinase-3 beta in rat hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Direct association of presenilin-1 with beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Insulin rescues retinal neurons from apoptosis by a phosphatidylinositol 3-kinase/Akt-mediated mechanism that reduces the activation of caspase-3.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Activation of glycogen synthase kinase 3 beta (GSK-3beta) by platelet activating factor mediates migration and cell death in cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Glycogen synthase kinase-3beta facilitates staurosporine- and heat shock-induced apoptosis. Protection by lithium

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Glycogen synthase kinase-3 beta activity is critical for neuronal death caused by inhibiting phosphatidylinositol 3-kinase or Akt but not for death caused by nerve growth factor withdrawal.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Selective small-molecule inhibitors of glycogen synthase kinase-3 activity protect primary neurones from death

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Molecular targets of lithium action

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

'Insulin-like' effects of lithium ion on isolated rat adipocytes. I. Stimulation of glycogenesis beyond glucose transport

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Glycogen synthase kinase-3beta, beta-catenin, and tau in postmortem bipolar brain

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

Anti-mitotic properties of indirubin-3'-monoxime, a CDK/GSK-3 inhibitor: induction of endoreplication following prophase arrest

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

The pathogenic L392V mutation of presenilin 1 decreases the affinity to glycogen synthase kinase-3 beta

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2801%2902266-3

7 January 2021

10.1016/S1471-4914(01)02266-3

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

11879773