(Q34553191)

7 October 2017

Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γ. (English)

1 reference

7 October 2017

3

Dennis McGonagle

0 references

Joseph S Ainscough

object named as

Joseph S Ainscough

1

0 references

author name string

Tom Macleod

2

1 reference

7 October 2017

Rosella Brakefield

4

1 reference

7 October 2017

Jens M Baron

5

1 reference

7 October 2017

Ade Alase

6

1 reference

7 October 2017

Miriam Wittmann

7

1 reference

7 October 2017

Martin Stacey

8

1 reference

7 October 2017

language of work or name

English

0 references

publication date

13 March 2017

1 reference

full work available at URL

7 October 2017

http://eprints.whiterose.ac.uk/112691

content deliverer

White Rose Research Online

object has role

postprint

1 reference

White Rose Research Online

Proceedings of the National Academy of Sciences of the United States of America

15 December 2018

published in

1 reference

7 October 2017

114

1 reference

7 October 2017

13

1 reference

7 October 2017

E2748-E2757

1 reference

Cell death and inflammation: the case for IL-1 family cytokines as the canonical DAMPs of the immune system

7 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Neutrophil Elastase-mediated proteolysis activates the anti-inflammatory cytokine IL-36 Receptor antagonist.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Distinct expression of interleukin (IL)-36α, β and γ, their antagonist IL-36Ra and IL-38 in psoriasis, rheumatoid arthritis and Crohn's disease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Cutting Edge: IL-36 Receptor Promotes Resolution of Intestinal Damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Update on psoriasis immunopathogenesis and targeted immunotherapy.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Regulation and function of interleukin-36 cytokines in homeostasis and pathological conditions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

IL-36γ (IL-1F9) is a biomarker for psoriasis skin lesions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

The interleukin-1 family: back to the future

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

The secretion of IL-1β and options for release

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Neutrophil recruitment and function in health and inflammation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Current and emerging systemic treatment strategies for psoriasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

PSORS2 is due to mutations in CARD14.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

DIRA, DITRA, and new insights into pathways of skin inflammation: what's in a name?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Understanding the mechanism of IL-1β secretion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36α, IL-36β, and IL-36γ) or antagonist (IL-36Ra) activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

IL-1F5, -F6, -F8, and -F9: a novel IL-1 family signaling system that is active in psoriasis and promotes keratinocyte antimicrobial peptide expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Role of IL-1beta in type 2 diabetes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

IL-1 pathways in inflammation and human diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Upregulation of cathepsin S in psoriatic keratinocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Molecular mechanisms involved in inflammasome activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Immunological and inflammatory functions of the interleukin-1 family

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Discontinued drugs in 2006: pulmonary-allergy, dermatological, gastrointestinal and arthritis drugs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

A pilot study of IL-1 inhibition by anakinra in acute gout

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

The inflammasome: first line of the immune response to cell stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Immune surveillance in the skin: mechanisms and clinical consequences

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

The secretory route of the leaderless protein interleukin 1beta involves exocytosis of endolysosome-related vesicles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5380102

IL-1RL2 and its ligands contribute to the cytokine network in psoriasis.

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1620954114

Novel IL36RN mutation in a Japanese case of early onset generalized pustular psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1620954114

Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1620954114

Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1620954114

Cutaneous reactions to recombinant cytokine therapy

21 January 2018

1 reference

12 December 2020

An essential role for Langerhans cell-derived IL-1 beta in the initiation of primary immune responses in skin

1 reference

12 December 2020

Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha

1 reference

12 December 2020

Stimulation of Langerhans cell migration in mice by tumour necrosis factor alpha and interleukin 1 beta

1 reference

12 December 2020

Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1620954114

1 reference

Dimensions Publication ID

7 October 2017

10.1073/PNAS.1620954114

0 references

CORE ID

155010125

0 references

1084152945

0 references

Microsoft Academic ID

0 references

1 reference

7 October 2017

PubMed publication ID

28289191

1 reference