(Q34556382)

11 November 2017

Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly (English)

1 reference

11 November 2017

0 references

Unnur Þorsteinsdóttir

18

Unnur Thorsteinsdottir

0 references

Ingileif Jonsdottir

6

Ingileif Jonsdottir

0 references

Thorunn Rafnar

17

Thorunn Rafnar

1 reference

11 November 2017

Thorgeir E. Thorgeirsson

Thorgeir E Thorgeirsson

7

0 references

Augustine Kong

Augustine Kong

21

0 references

Patrick Sulem

16

Patrick Sulem

1 reference

11 November 2017

Daníel F. Guðbjartsson

19

Daniel F Gudbjartsson

1 reference

11 November 2017

22

Kari Stefansson

1 reference

11 November 2017

12

Laufey Tryggvadottir

1 reference

11 November 2017

Florian Zink

1

1 reference

11 November 2017

Simon N Stacey

2

1 reference

11 November 2017

Gudmundur L Norddahl

3

1 reference

11 November 2017

Michael L Frigge

4

1 reference

11 November 2017

Olafur T Magnusson

5

1 reference

11 November 2017

Asgeir Sigurdsson

8

1 reference

11 November 2017

Sigurjon A Gudjonsson

9

1 reference

11 November 2017

Julius Gudmundsson

10

1 reference

11 November 2017

Jon G Jonasson

11

1 reference

11 November 2017

Thorvaldur Jonsson

13

1 reference

11 November 2017

Agnar Helgason

14

1 reference

11 November 2017

Arnaldur Gylfason

15

1 reference

11 November 2017

Gisli Masson

20

1 reference

11 November 2017

language of work or name

English

0 references

publication date

8 May 2017

1 reference

11 November 2017

1 reference

11 November 2017

130

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11 November 2017

6

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11 November 2017

742-752

1 reference

describes a project that uses

11 November 2017

1 reference

10 June 2022

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&rettype=xml&id=5553576

cites work

Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult Animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Somatic Mosaic Mutations in PPM1D and TP53 in the Blood of Women With Ovarian Carcinoma.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

PPM1D Mosaic Truncating Variants in Ovarian Cancer Cases May Be Treatment-Related Somatic Mutations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Stochastic modeling reveals an evolutionary mechanism underlying elevated rates of childhood leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Large-scale whole-genome sequencing of the Icelandic population

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Bone marrow failure and the telomeropathies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Estimating telomere length from whole genome sequence data

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

The germline sequence variant rs2736100_C in TERT associates with myeloproliferative neoplasms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Short telomeres: from dyskeratosis congenita to sporadic aplastic anemia and malignancy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

The origin and evolution of mutations in acute myeloid leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Universal patterns of stem cell fate in cycling adult tissues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

The replication rate of human hematopoietic stem cells in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Hematopoietic stem cell heterogeneity: subtypes, not unpredictable behavior.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Parental origin of sequence variants associated with complex diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Skewing of X-inactivation ratios in blood cells of aging women is confirmed by independent methodologies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Detection of sharing by descent, long-range phasing and haplotype imputation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

(A)symmetric stem cell replication and cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Allometric scaling of the active hematopoietic stem cell pool across mammals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Clonal haemopoiesis in normal elderly women: implications for the myeloproliferative disorders and myelodysplastic syndromes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Nonrandom X-inactivation patterns in normal females: lyonization ratios vary with age.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Evidence for a multistep pathogenesis of a myelodysplastic syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Clonal analysis of chronic myeloproliferative disorders using X-linked DNA polymorphisms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

X-chromosome inactivation patterns using HPRT and PGK polymorphisms in haematologically normal and post-chemotherapy females.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Probable clonal origin of acute myeloblastic leukemia following radiation and chemotherapy of colon cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

PPM1D mutations in circulating white blood cells and the risk for ovarian cancer.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Age-associated aneuploidy: loss of Y chromosome from human bone marrow cells with aging.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5553576

Pigmentary traits, ethnic origin, benign nevi, and family history as risk factors for cutaneous malignant melanoma

27 October 2018

1 reference

12 December 2020

Clonality and X-inactivation patterns in hematopoietic cell populations detected by the highly informative M27 beta DNA probe

1 reference

12 December 2020

Evidence that essential thrombocythemia is a clonal disorder with origin in a multipotent stem cell

1 reference

12 December 2020

Change of Human Chromosome Count Distributions with Age: Evidence for a Sex Difference

1 reference

12 December 2020

10.1182/BLOOD-2017-02-769869

Identifiers

DOI

1 reference

11 November 2017

1 reference

11 November 2017

1 reference