(Q34556912)

3 August 2017

title

Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells (English)

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3 August 2017

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9

Nico Ghilardi

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author name string

Marcel Batten

1

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3 August 2017

Ji Li

2

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3 August 2017

Sothy Yi

3

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3 August 2017

Noelyn M Kljavin

4

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3 August 2017

Dimitry M Danilenko

5

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3 August 2017

Sophie Lucas

6

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3 August 2017

James Lee

7

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3 August 2017

Frederic J de Sauvage

8

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3 August 2017

language of work or name

English

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publication date

13 August 2006

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3 August 2017

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3 August 2017

volume

7

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3 August 2017

issue

9

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3 August 2017

page(s)

929-936

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https://scigraph.springernature.com/pub.10.1038/ni1375

3 August 2017

exact match

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cites work

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

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7 January 2021

IL-27 and IFN-αSignal via Stat1 and Stat3 and Induce T-Bet and IL-12Rβ2 in Naive T Cells

1 reference

7 January 2021

IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms

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7 January 2021

Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

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7 January 2021

Development of Th1-type immune responses requires the type I cytokine receptor TCCR

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7 January 2021

WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

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7 January 2021

Cloning and characterization of a novel class I cytokine receptor

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7 January 2021

The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis

1 reference

7 January 2021

IL-27 signaling compromises control of bacterial growth in mycobacteria-infected mice

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7 January 2021

The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection

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7 January 2021

WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection

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7 January 2021

The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity

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7 January 2021

WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production

1 reference

7 January 2021

Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice

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7 January 2021

Hyperproduction of proinflammatory cytokines by WSX-1-deficient NKT cells in concanavalin A-induced hepatitis

1 reference

7 January 2021

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

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7 January 2021

Understanding the IL-23-IL-17 immune pathway

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7 January 2021

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

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7 January 2021

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

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7 January 2021

Microbial lipopeptides induce the production of IL-17 in Th cells.

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7 January 2021

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

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7 January 2021

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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7 January 2021

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

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7 January 2021

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

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7 January 2021

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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7 January 2021

Transforming growth factor-beta induces development of the T(H)17 lineage

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7 January 2021

IL-27 limits IL-2 production during Th1 differentiation.

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7 January 2021

IL-27 suppresses CD28-mediated [correction of medicated] IL-2 production through suppressor of cytokine signaling 3.

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7 January 2021

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

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7 January 2021

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

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7 January 2021

Interleukin-17 family members and inflammation

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7 January 2021

Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation

1 reference

7 January 2021

Granulocyte macrophage colony-stimulating factor: a new putative therapeutic target in multiple sclerosis.

1 reference

7 January 2021

STAT3 and NF-kappaB signal pathway is required for IL-23-mediated IL-17 production in spontaneous arthritis animal model IL-1 receptor antagonist-deficient mice

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7 January 2021

Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells

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7 January 2021

IL-2 and autoimmune disease

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7 January 2021

T helper 1-inducing property of IL-27/WSX-1 signaling is required for the induction of experimental colitis

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7 January 2021

A protective role for IL-6 during early infection with Toxoplasma gondii

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7 January 2021

Impaired resistance to the development of toxoplasmic encephalitis in interleukin-6-deficient mice

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7 January 2021

Interleukin-6 is required for parasite specific response and host resistance to Trypanosoma cruzi.

1 reference

7 January 2021

Interleukin-17/interleukin-17 receptor-mediated signaling is important for generation of an optimal polymorphonuclear response against Toxoplasma gondii infection

1 reference

7 January 2021

Pathological role of IL-6 in the experimental allergic bronchial asthma in mice

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7 January 2021

Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system

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7 January 2021

Identifiers

DOI

10.1038/NI1375

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Dimensions Publication ID

3 August 2017

1026540507

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