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Molecular biology of lung cancer: clinical implications.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
11901922
retrieved
3 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Molecular biology of lung cancer: clinical implications.
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
11901922
retrieved
3 August 2017
main subject
molecular biology
0 references
author name string
Kwun M Fong
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11901922
retrieved
3 August 2017
John D Minna
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
11901922
retrieved
3 August 2017
publication date
1 March 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
11901922
retrieved
3 August 2017
published in
Clinics in Chest Medicine
1 reference
stated in
Europe PubMed Central
PubMed ID
11901922
retrieved
3 August 2017
volume
23
1 reference
stated in
Europe PubMed Central
PubMed ID
11901922
retrieved
3 August 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
11901922
retrieved
3 August 2017
page(s)
83-101
1 reference
stated in
Europe PubMed Central
PubMed ID
11901922
retrieved
3 August 2017
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Prognostic value of the expression of p53, bcl-2, and bax oncoproteins, and neovascularization in patients with radically resected non-small-cell lung cancer.
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Phase I studies of anti-epidermal growth factor receptor chimeric antibody C225 alone and in combination with cisplatin.
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Molecular epidemiology of human cancer risk: gene-environment interactions and p53 mutation spectrum in human lung cancer
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Prognostic significance of CCND1 (cyclin D1) overexpression in primary resected non-small-cell lung cancer
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Abnormal expression of CCND1 and RB1 in resection margin epithelia of lung cancer patients
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Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression
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Genetic polymorphisms in DNA repair genes and risk of lung cancer.
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p21waf1/cip1mda-6 expression in non-small-cell lung cancer: relationship to survival.
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Microsatellite alterations in plasma DNA of small cell lung cancer patients.
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Mutations in OGG1, a gene involved in the repair of oxidative DNA damage, are found in human lung and kidney tumours.
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Extracellular matrix expression in metastasizing and nonmetastasizing adenocarcinomas of the lung
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The pattern of K-ras mutation in pulmonary adenocarcinoma defines a new pathway of tumour development in the human lung
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Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer
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Molecular biologic substaging of stage I lung cancer according to gender and histology
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Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.
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Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.
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Bombesin receptor structure and expression in human lung carcinoma cell lines.
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Angiogenesis as a Prognostic Indicator of Survival in Non-Small-Cell Lung Carcinoma: a Prospective Study
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Bcl-2 protein: a prognostic factor inversely correlated to p53 in non-small-cell lung cancer
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Neoangiogenesis and p53 protein in lung cancer: their prognostic role and their relation with vascular endothelial growth factor (VEGF) expression
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Mutation analysis of the PTEN/MMAC1 gene in lung cancer
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Widely dispersed p53 mutation in respiratory epithelium. A novel mechanism for field carcinogenesis
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Mechanisms of p16INK4A inactivation in non small-cell lung cancers
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Prognostic significance of K-ras codon 12 mutations in patients with resected stage I and II non-small-cell lung cancer
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Cancer statistics, 2000.
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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
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Immunoreactivity for hepatocyte growth factor/scatter factor and its receptor, met, in human lung carcinomas and malignant mesotheliomas
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Early Lung Cancer Action Project: overall design and findings from baseline screening.
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MDM2 gene amplification and expression in non-small-cell lung cancer: immunohistochemical expression of its protein is a favourable prognostic marker in patients without p53 protein accumulation
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bcl-2 oncoprotein in surgically resected non-small cell lung cancer: possibly favorable prognostic factor in association with low incidence of distant metastasis
1 reference
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Crossref
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Telomerase activity in small-cell and non-small-cell lung cancers
1 reference
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Crossref
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inferred from DOI database lookup
Prognostic significance of p53 mutations in non-small cell lung cancer: a meta-analysis of 829 cases from eight published studies
1 reference
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Crossref
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Role of glutathione S-transferase GSTM1, GSTM3, GSTP1 and GSTT1 genotypes in modulating susceptibility to smoking-related lung cancer
1 reference
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Crossref
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Expression of bcl-2--protein in small cell lung cancer
1 reference
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Crossref
reference URL
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The TP53 genotype but not immunohistochemical result is predictive of response to cisplatin-based neoadjuvant therapy in stage III non-small cell lung cancer
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7 January 2021
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Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study
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Antitumor activity of a monoclonal antibody directed against gastrin-releasing peptide in patients with small cell lung cancer.
1 reference
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Crossref
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Differential inactivation of CDKN2 and Rb protein in non-small-cell and small-cell lung cancer cell lines.
1 reference
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Crossref
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Crossref
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1 reference
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1 reference
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1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
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1 reference
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7 January 2021
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Molecular pathologic substaging in 244 stage I non-small-cell lung cancer patients: clinical implications.
1 reference
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Crossref
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7 January 2021
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7 January 2021
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1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Identification of novel regions of altered DNA copy number in small cell lung tumors
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Serum p53 antibodies as early markers of lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Clonal genetic alterations in the lungs of current and former smokers
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations of P16 (MTS1) in node-positive non-small cell lung carcinomas
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
p53 mutations predict non-small cell lung carcinoma response to radiotherapy
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
The role of pRb2/p130 protein in diagnosing lung carcinoma on fine needle aspiration biopsies
1 reference
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Crossref
reference URL
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7 January 2021
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1 reference
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Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel molecular staging protocol for non-small cell lung cancer
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic significance of abnormal p53 accumulation in primary, resected non-small-cell lung cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Delineation of the centromeric and telomeric chromosome segment 11p15.5 lung cancer suppressor regions LOH11A and LOH11B.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion mapping of the short arm of chromosome 8 in non-small cell lung carcinoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vascular endothelial growth factor and lymph node metastasis in primary lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression and activation of hepatocyte growth factor/scatter factor in human non-small-cell lung carcinomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deletion mapping of chromosome 2 in human lung carcinoma
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein expression and functional analysis of the FHIT gene in human tumor cells
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunocytochemical markers in stage I lung cancer: relevance to prognosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
bcl-2 protein in non-small-cell lung carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of prognostic significance of epidermal growth factor receptor and the oncoprotein p185HER-2 in patients with systemically untreated non-small-cell lung cancer: an immunohistochemical study on cryosections
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-like growth factor expression in human cancer cell lines
1 reference
stated in
Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational activation of the K-ras oncogene and the effect of chemotherapy in advanced adenocarcinoma of the lung: a prospective study
1 reference
stated in
Crossref
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced survival in patients with stage-I non-small-cell lung cancer associated with DNA-replication errors
1 reference
stated in
Crossref
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7 January 2021
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inferred from DOI database lookup
Meta-analysis of studies of the CYP2D6 polymorphism in relation to lung cancer and Parkinson's disease.
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Gene replacement strategies for treating non-small cell lung cancer
1 reference
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Crossref
reference URL
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retrieved
7 January 2021
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inferred from DOI database lookup
Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intragenic mutations of the p16(INK4), p15(INK4B) and p18 genes in primary non-small-cell lung cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Non-ocular cancer in relatives of retinoblastoma patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A follow-up study of progression from dysplasia to squamous cell carcinoma with immunohistochemical examination of p53 protein overexpression in the bronchi of ex-chromate workers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus-mediated wild-type p53 gene transfer in patients receiving chemotherapy for advanced non-small-cell lung cancer: results of a multicenter phase II study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased cancer risk among relatives of nonsmoking lung cancer cases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Segregation analysis of smoking-associated malignancies: evidence for Mendelian inheritance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sex-specific expression of gastrin-releasing peptide receptor: relationship to smoking history and risk of lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microsatellite DNA instability in COPD
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TP53 gene mutations in plasma DNA of cancer patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relationship between K-ras oncogene activation and smoking in adenocarcinoma of the human lung.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
K-ras oncogene activation as a prognostic marker in adenocarcinoma of the lung
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extensive areas of aneuploidy are present in the respiratory epithelium of lung cancer patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cadherin and catenin expression in normal human bronchial epithelium and non-small cell lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mass screening for lung cancer with mobile spiral computed tomography scanner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The FHIT gene 3p14.2 is abnormal in lung cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular epidemiology of lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bombesin-like peptides and airway repair: a recapitulation of lung development?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced E-cadherin expression is associated with increased lymph node metastasis and unfavorable prognosis in non-small cell lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic value of the immunohistochemical detection of p16INK4 expression in nonsmall cell lung carcinoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Detection of aneuploidy in interphase nuclei from non-small cell lung carcinomas by fluorescence in situ hybridization using chromosome-specific repetitive DNA probes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53: a frequent target for genetic abnormalities in lung cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunohistochemical detection of basic fibroblast growth factor as a prognostic indicator in pulmonary adenocarcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Advances in the analysis of chromosome alterations in human lung carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal FHIT transcripts found in both lung cancer and normal lung tissue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Familial aggregation of lung cancer among hospital patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Correlation of intrinsic chemoresistance of non-small-cell lung cancer cell lines with HER-2/neu gene expression but not with ras gene mutations.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High K-ras mutation rates in goblet-cell-type adenocarcinomas of the lungs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Allelotyping demonstrates common and distinct patterns of chromosomal loss in human lung cancer types
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Promoter Methylation and Silencing of the Retinoic Acid Receptor- Gene in Lung Carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic value of vascular endothelial growth factor and its receptor Flt-1 in squamous cell lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic value of basic fibroblast growth factor and its receptor (FGFR-1) in patients with non-small cell lung carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations of the PPP2R1B gene in human lung and colon cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Refined mapping of two regions of loss of heterozygosity on chromosome band 11q23 in lung cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular damage in the bronchial epithelium of current and former smokers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metabolic polymorphisms in carcinogen metabolising enzymes and cancer susceptibility
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evaluation of telomerase activity in bronchial lavage as a potential diagnostic marker for malignant lung disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered retinoblastoma protein expression and prognosis in early-stage non-small-cell lung carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutational analysis of p73 and p53 in human cancer cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of Glut1 and Glut3 in stage I nonsmall cell lung carcinoma is associated with poor survival
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effective treatment of early endobronchial cancer with regional administration of liposome-p53 complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0272-5231%2803%2900062-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0272-5231(03)00062-5
1 reference
stated in
Europe PubMed Central
PubMed ID
11901922
retrieved
3 August 2017
PubMed ID
11901922
1 reference
stated in
Europe PubMed Central
PubMed ID
11901922
retrieved
3 August 2017
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