(Q34574445)

3 August 2017

Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a). (English)

1 reference

3 August 2017

3

John M Sedivy

1 reference

3 August 2017

Isil Guney

1

1 reference

PubMed ID

16537449

3 August 2017

Shirley Wu

series ordinal

2

1 reference

PubMed ID

16537449

3 August 2017

language of work or name

English

0 references

publication date

28 February 2006

1 reference

Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

1 reference

3 August 2017

103

1 reference

3 August 2017

3645-3650

1 reference

3 August 2017

10

1 reference

Ink4a/Arf expression is a biomarker of aging

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Mitogen stimulation cooperates with telomere shortening to activate DNA damage responses and senescence signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

A DNA damage checkpoint response in telomere-initiated senescence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

DNA damage foci at dysfunctional telomeres

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Reversal of human cellular senescence: roles of the p53 and p16 pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Werner syndrome protein limits MYC-induced cellular senescence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Genomic targets of the human c-Myc protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Abolition of cyclin-dependent kinase inhibitor p16Ink4a and p21Cip1/Waf1 functions permits Ras-induced anchorage-independent growth in telomerase-immortalized human fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Lentivirus-delivered stable gene silencing by RNAi in primary cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

A large scale genetic analysis of c-Myc-regulated gene expression patterns

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Programming off and on states in chromatin: mechanisms of Polycomb and trithorax group complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

The myc oncogene: MarvelouslY Complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Proliferation, cell cycle and apoptosis in cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

MYC oncogenes and human neoplastic disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1450136

Tumor suppressor p16INK4a determines sensitivity of human cells to transformation by cooperating cellular oncogenes

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600069103

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600069103

Ink4a/Arf expression is a biomarker of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600069103

The tumor-suppressive functions of the human INK4A locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0600069103

Real-time imaging of transcriptional activation in live cells reveals rapid up-regulation of the cyclin-dependent kinase inhibitor gene CDKN1A in replicative cellular senescence

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16537449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/16537449

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0600069103

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference

PubMed ID

16537449