(Q34580781)

3 August 2017

title

Engineering anthrax toxin variants that exclusively form octamers and their application to targeting tumors (English)

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3 August 2017

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13

Stephen H Leppla

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3 August 2017

6

Mahtab Moayeri

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3 August 2017

5

Shihui Liu

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3 August 2017

3

Devorah Crown

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3 August 2017

11

Alexander N Wein

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3 August 2017

2

Rasem J Fattah

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3 August 2017

14

Clinton E Leysath

1 reference

3 August 2017

Damilola D Phillips

1

1 reference

3 August 2017

Yi Zhang

4

1 reference

3 August 2017

Elizabeth R Fischer

7

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3 August 2017

Bryan T Hansen

8

1 reference

3 August 2017

Rodolfo Ghirlando

9

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3 August 2017

Ekaterina M Nestorovich

10

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3 August 2017

Lacy Simons

12

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3 August 2017

language of work or name

English

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publication date

7 February 2013

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Journal of Biological Chemistry

3 August 2017

published in

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3 August 2017

volume

288

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3 August 2017

issue

13

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3 August 2017

page(s)

9058-9065

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Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Domain Flexibility Modulates the Heterogeneous Assembly Mechanism of Anthrax Toxin Protective Antigen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

A Bacillus anthracis strain deleted for six proteases serves as an effective host for production of recombinant proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Noninvasive imaging technologies reveal edema toxin as a key virulence factor in anthrax

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Anthrax toxin receptor drives protective antigen oligomerization and stabilizes the heptameric and octameric oligomer by a similar mechanism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Cellular and systemic effects of anthrax lethal toxin and edema toxin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

The Protective Antigen Component of Anthrax Toxin Forms Functional Octameric Complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

The surface of Bacillus anthracis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Analytical ultracentrifugation: sedimentation velocity and sedimentation equilibrium

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Anthrax toxin: receptor binding, internalization, pore formation, and translocation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Intermolecular complementation achieves high-specificity tumor targeting by anthrax toxin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Binary bacterial toxins: biochemistry, biology, and applications of common Clostridium and Bacillus proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Structure of heptameric protective antigen bound to an anthrax toxin receptor: a role for receptor in pH-dependent pore formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Involvement of domain 3 in oligomerization by the protective antigen moiety of anthrax toxin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Oligomerization of anthrax toxin protective antigen and binding of lethal factor during endocytic uptake into mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Staphylococcal alpha-hemolysin can form hexamers in phospholipid bilayers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Internalization of a Bacillus anthracis protective antigen-c-Myc fusion protein mediated by cell surface anti-c-Myc antibodies.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Anthrax protective antigen forms oligomers during intoxication of mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3610978

Targeting of tumor cells by cell surface urokinase plasminogen activator-dependent anthrax toxin

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M113.452110

Hydrophobic residues Phe552, Phe554, Ile562, Leu566, and Ile574 are required for oligomerization of anthrax protective antigen

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M113.452110

A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo

21 January 2018

1 reference

12 December 2020

Optimized production and purification of Bacillus anthracis lethal factor

1 reference

12 December 2020

Hydrodynamics of nanoscopic tubulin rings in dilute solutions

1 reference

12 December 2020

Tumor cell-selective cytotoxicity of matrix metalloproteinase-activated anthrax toxin

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M113.452110

1 reference

OpenCitations bibliographic resource ID

3 August 2017

0 references

1 reference

3 August 2017

1 reference