(Q34580969)

25368144

3 August 2017

title

Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome (English)

1 reference

3 August 2017

1 reference

2

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7 June 2020

Manuel F Juette

9

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7 June 2020

Scott C Blanchard

15

1 reference

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7 June 2020

13

Jamie H D Cate

1 reference

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7 June 2020

author name string

Nelson B Olivier

1

1 reference

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7 June 2020

Jonas Noeske

3

1 reference

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7 June 2020

Gregory S Basarab

4

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7 June 2020

Erin Code

5

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7 June 2020

Andrew D Ferguson

6

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7 June 2020

Ning Gao

7

1 reference

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7 June 2020

Jian Huang

8

1 reference

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7 June 2020

Stephania Livchak

10

1 reference

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7 June 2020

Matthew D Miller

11

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7 June 2020

D Bryan Prince

12

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7 June 2020

Ed T Buurman

14

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7 June 2020

language of work or name

English

0 references

publication date

3 November 2014

1 reference

25368144

Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

published in

1 reference

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7 June 2020

volume

111

1 reference

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7 June 2020

issue

46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25368144%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

page(s)

16274-16279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25368144%20AND%20SRC:MED&resulttype=core&format=json

Tools for characterizing bacterial protein synthesis inhibitors

7 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

How good are my data and what is the resolution?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Mechanistic insights into antibiotic action on the ribosome through single-molecule fluorescence imaging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Unraveling the dynamics of ribosome translocation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Structural basis for TetM-mediated tetracycline resistance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Allosteric control of the ribosome by small-molecule antibiotics.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Pharmaceutical therapies to recode nonsense mutations in inherited diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

How should we think about the ribosome?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Target- and resistance-based mechanistic studies with TP-434, a novel fluorocycline antibiotic.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Data processing and analysis with the autoPROC toolbox

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Antibiotic selectivity for prokaryotic vs. eukaryotic decoding sites

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Conformational sampling of aminoacyl-tRNA during selection on the bacterial ribosome.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Features and development of Coot

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

PHENIX: a comprehensive Python-based system for macromolecular structure solution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Aminoglycoside activity observed on single pre-translocation ribosome complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Structures of the ribosome in intermediate states of ratcheting

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Federal funding for the study of antimicrobial resistance in nosocomial pathogens: no ESKAPE

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Negamycin Binds to the Wall of the Nascent Chain Exit Tunnel of the 50S Ribosomal Subunit

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

tRNA dynamics on the ribosome during translation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

When the message goes awry: disease-producing mutations that influence mRNA content and performance.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

A new antibiotic, negamycin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Mechanism of action of negamycin in Escherichia coli K12. II. Miscoding activity in polypeptide synthesis directed by snythetic polynucleotide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Mechanism of action of negamycin in Escherichia coli K12. I. Inhibition of initiation of protein synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Negamycin, a miscoding antibiotic with a unique structure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Streptococcal tetracycline resistance mediated at the level of protein synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

Interaction of antibiotics with functional sites in 16S ribosomal RNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246262

N- and C-terminal modifications of negamycin.

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1414401111

Conformationally restricted analogs of deoxynegamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1414401111

Negamycin restores dystrophin expression in skeletal and cardiac muscles of mdx mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1414401111

tRNA selection and kinetic proofreading in translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1414401111

The tetracycline resistance protein Tet(o) perturbs the conformation of the ribosomal decoding centre

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1414401111

Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1414401111

Continuum electrostatic methods applied to pH-dependent properties of antibody-antigen association

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1414401111

[19] Preparation of functional ribosomal complexes and effect of buffer conditions on tRNA positions observed by cryoelectron microscopy

21 January 2018

1 reference

12 December 2020

Negamycin, a novel hydrazide antibiotic

1 reference

12 December 2020

Total syntheses of negamycin and the antipode

1 reference

12 December 2020

Negamycin inhibits termination of protein synthesis directed by phage f2 RNA in vitro

1 reference

12 December 2020

Specific inhibition of the termination process of protein synthesis by negamycin

1 reference

12 December 2020

Inhibitory effect of negamycin on polysomal ribosomes of Escherichia coli

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1414401111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25368144%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25368144%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

25368144

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25368144%20AND%20SRC:MED&resulttype=core&format=json