(Q34594036)

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Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: a comprehensive study using the most potent and broadly neutralizing monoclonal antibodies.

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16 February 2020

Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: a comprehensive study using the most potent and broadly neutralizing monoclonal antibodies (English)

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16 February 2020

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16 February 2020

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16 February 2020

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P D Kwong

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16 February 2020

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M Bouvin-Pley

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16 February 2020

M Morgand

2

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16 February 2020

L Meyer

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16 February 2020

C Goujard

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16 February 2020

A Moreau

5

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16 February 2020

H Mouquet

6

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16 February 2020

M Nussenzweig

7

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16 February 2020

C Pace

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16 February 2020

D Ho

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16 February 2020

P J Bjorkman

10

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16 February 2020

M Pancera

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16 February 2020

P Poignard

15

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16 February 2020

F Barin

16

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16 February 2020

M Braibant

17

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16 February 2020

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17 September 2014

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16 February 2020

Journal of Virology

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16 February 2020

88

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16 February 2020

13910-13917

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16 February 2020

23

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16 February 2020

Passive transfer of modest titers of potent and broadly neutralizing anti-HIV monoclonal antibodies block SHIV infection in macaques

1 reference

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7 July 2018

Impact of clade, geography, and age of the epidemic on HIV-1 neutralization by antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248973

7 July 2018

Anti-MPER antibodies with heterogeneous neutralization capacity are detectable in most untreated HIV-1 infected individuals.

1 reference

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7 July 2018

Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4248973

7 July 2018

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers

1 reference

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7 July 2018

Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike

1 reference

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7 July 2018

Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection

1 reference

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7 July 2018

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

1 reference

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7 July 2018

Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia

1 reference

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7 July 2018

HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice

1 reference

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7 July 2018

Bispecific antibodies directed to CD4 domain 2 and HIV envelope exhibit exceptional breadth and picomolar potency against HIV-1

1 reference

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7 July 2018

Evidence for a continuous drift of the HIV-1 species towards higher resistance to neutralizing antibodies over the course of the epidemic

1 reference

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7 July 2018

Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites

1 reference

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7 July 2018

Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies

1 reference

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7 July 2018

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

1 reference

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7 July 2018

Straightforward selection of broadly neutralizing single-domain antibodies targeting the conserved CD4 and coreceptor binding sites of HIV-1 gp120

1 reference

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7 July 2018

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

1 reference

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7 July 2018

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

1 reference

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7 July 2018

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

1 reference

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7 July 2018

Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo

1 reference

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7 July 2018

A Blueprint for HIV Vaccine Discovery

1 reference

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7 July 2018

Previously transmitted HIV-1 strains are preferentially selected during subsequent sexual transmissions

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7 July 2018

Broadly neutralizing antibodies developed by an HIV-positive elite neutralizer exact a replication fitness cost on the contemporaneous virus

1 reference

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7 July 2018

Broad neutralization by a combination of antibodies recognizing the CD4 binding site and a new conformational epitope on the HIV-1 envelope protein

1 reference

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7 July 2018

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

1 reference

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Increasing the potency and breadth of an HIV antibody by using structure-based rational design

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A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

1 reference

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7 July 2018

Broad neutralization coverage of HIV by multiple highly potent antibodies

1 reference

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Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

1 reference

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The neutralization breadth of HIV-1 develops incrementally over four years and is associated with CD4+ T cell decline and high viral load during acute infection

1 reference

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1 reference

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1 reference

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Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

1 reference

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Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

1 reference

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1 reference

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The role of antibodies in HIV vaccines

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Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

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1 reference

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In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth

1 reference

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1 reference

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Broad HIV-1 neutralization mediated by CD4-binding site antibodies

1 reference

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In vivo and in vitro escape from neutralizing antibodies 2G12, 2F5, and 4E10.

1 reference

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Antibody domain exchange is an immunological solution to carbohydrate cluster recognition

1 reference

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1 reference

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A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic seropositive individuals

1 reference

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Adaptation of HIV-1 envelope gp120 to humoral immunity at a population level

1 reference

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Antibodies to conserved epitopes of the HIV-1 envelope in sera from long-term non-progressors: prevalence and association with neutralizing activity

1 reference

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9 December 2018

Identifiers

10.1128/JVI.02083-14

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Europe PubMed Central

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16 February 2020

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Europe PubMed Central

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16 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25231299%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

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