(Q34606034)

3 August 2017

title

Empirical fitness landscapes reveal accessible evolutionary paths (English)

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3 August 2017

4

Sander J Tans

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3 August 2017

Frank J Poelwijk

1

1 reference

3 August 2017

Daniel J Kiviet

series ordinal

2

1 reference

3 August 2017

Daniel M Weinreich

series ordinal

3

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3 August 2017

language of work or name

English

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publication date

1 January 2007

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3 August 2017

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3 August 2017

volume

445

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3 August 2017

issue

7126

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3 August 2017

page(s)

383-386

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Chemical Paleogenetics. Molecular "Restoration Studies" of Extinct Forms of Life

3 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Natural Selection and the Concept of a Protein Space

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7 January 2021

Ancestral lysozymes reconstructed, neutrality tested, and thermostability linked to hydrocarbon packing.

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https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

The ribonuclease from an extinct bovid ruminant

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https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Evolution of coral pigments recreated.

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https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Resurrecting ancient genes: experimental analysis of extinct molecules

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https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Metastable evolutionary dynamics: crossing fitness barriers or escaping via neutral paths?

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Darwinian evolution can follow only very few mutational paths to fitter proteins

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Evolutionary potential of a duplicated repressor-operator pair: simulating pathways using mutation data

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Missense meanderings in sequence space: a biophysical view of protein evolution

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Protein stability promotes evolvability

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

The biochemical architecture of an ancient adaptive landscape

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

The selective cause of an ancient adaptation.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Evolution of hormone-receptor complexity by molecular exploitation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Robustness in simple biochemical networks

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

https://api.crossref.org/works/10.1038%2FNATURE05451

1 reference

7 January 2021

Biological robustness

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Robustness of cellular functions

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Stochastic gene expression in fluctuating environments

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Phenotypic diversity, population growth, and information in fluctuating environments.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

How enzymes adapt: lessons from directed evolution

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Microbial genetics: Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

In vivo molecular evolution reveals biophysical origins of organismal fitness

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Optimality and evolutionary tuning of the expression level of a protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Catalytic mechanism of NADP(+)-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and NADP+ complexes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Determinants of cofactor specificity in isocitrate dehydrogenase: structure of an engineered NADP+ --> NAD+ specificity-reversal mutant

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Plasticity in protein-DNA recognition: lac repressor interacts with its natural operator 01 through alternative conformations of its DNA-binding domain

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

Altered specificity in DNA binding by the lac repressor: a mutant lac headpiece that mimics the gal repressor

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05451

7 January 2021

MOLMOL: a program for display and analysis of macromolecular structures

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7 January 2021

Identifiers

DOI

10.1038/NATURE05451

1 reference

Dimensions Publication ID

3 August 2017

1013423006

0 references

1 reference