(Q34610822)

3 August 2017

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title

The clinical pharmacokinetics of escitalopram (English)

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3 August 2017

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Niranjan Rao

1

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3 August 2017

1 January 2007

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Clinical Pharmacokinetics

3 August 2017

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3 August 2017

46

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3 August 2017

281-290

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3 August 2017

4

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https://scigraph.springernature.com/pub.10.2165/00003088-200746040-00002

3 August 2017

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12 December 2020

Drug interactions with newer antidepressants: role of human cytochromes P450

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Steady-state pharmacokinetics of the enantiomers of citalopram and its metabolites in humans

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The pharmacokinetics of escitalopram after oral and intravenous administration of single and multiple doses to healthy subjects

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Tricyclic antidepressant plasma levels after augmentation with citalopram: a case study

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The emerging role of cytochrome P450 3A in psychopharmacology

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Fixed-dose trial of the single isomer SSRI escitalopram in depressed outpatients

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Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities

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Metabolism of citalopram enantiomers in CYP2C19/CYP2D6 phenotyped panels of healthy Swedes

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Carbamazepine augmentation in depressive patients non-responding to citalopram: a pharmacokinetic and clinical pilot study

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The kinetics of citalopram: single and multiple dose studies in man

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Escitalopram in the treatment of generalized anxiety disorder: double-blind, placebo controlled, flexible-dose study

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Selective serotonin reuptake inhibitors and cytochrome P-450 mediated drug-drug interactions: an update

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Non-response to citalopram in depressive patients: pharmacokinetic and clinical consequences of a fluvoxamine augmentation

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The pharmacological effect of citalopram residues in the (S)-(+)-enantiomer

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Efficacy comparison of escitalopram and citalopram in the treatment of major depressive disorder: pooled analysis of placebo-controlled trials.

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High-performance liquid chromatographic determination of citalopram and four of its metabolites in plasma and urine samples from psychiatric patients

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Fluvoxamine inhibits the CYP2C19-catalysed metabolism of proguanil in vitro.

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Stereoselective biotransformation of the selective serotonin reuptake inhibitor citalopram and its demethylated metabolites by monoamine oxidases in human liver

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Investigation of multiple dose citalopram on the pharmacokinetics and pharmacodynamics of racemic warfarin.

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Inhibition of P-glycoprotein by newer antidepressants

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The effect of cimetidine or omeprazole on the pharmacokinetics of escitalopram in healthy subjects

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Single-dose pharmacokinetics of citalopram in patients with moderate renal insufficiency or hepatic cirrhosis compared with healthy subjects.

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Escitalopram versus citalopram: the surprising role of the R-enantiomer

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The pharmacokinetics of escitalopram in patients with hepatic impairment

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Effect of citalopram on plasma levels of oral theophylline.

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Lack of citalopram effect on oral digoxin pharmacokinetics

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Transport mechanisms for the antidepressant citalopram in brain microvessel endothelium.

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Escitalopram : a review of its use in the management of major depressive and anxiety disorders

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Penetration of amitriptyline, but not of fluoxetine, into brain is enhanced in mice with blood-brain barrier deficiency due to mdr1a P-glycoprotein gene disruption

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Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram

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Determination of the enantiomers of citalopram, its demethylated and propionic acid metabolites in human plasma by chiral HPLC

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An evaluation of the potential for pharmacokinetic interaction between escitalopram and the cytochrome P450 3A4 inhibitor ritonavir

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Lack of effect of citalopram on the steady-state pharmacokinetics of carbamazepine in healthy male subjects

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A double-blind, placebo-controlled study of citalopram with and without lithium in the treatment of therapy-resistant depressive patients: a clinical, pharmacokinetic, and pharmacogenetic investigation

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Escitalopram 10 mg/day is effective and well tolerated in a placebo-controlled study in depression in primary care

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12 December 2020

Escitalopram continuation treatment prevents relapse of depressive episodes

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abcb1ab P-glycoprotein is involved in the uptake of citalopram and trimipramine into the brain of mice

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12 December 2020

In vitro biotransformation of the selective serotonin reuptake inhibitor citalopram, its enantiomers and demethylated metabolites by monoamine oxidase in rat and human brain preparations

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12 December 2020

Lack of interaction between citalopram and the CYP3A4 substrate triazolam

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12 December 2020

Metabolism and excretion of citalopram in man: identification of O-acyl- and N-glucuronides

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12 December 2020

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12 December 2020

Fluoxetine augmentation in citalopram non-responders: pharmacokinetic and clinical consequences

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Cytochrome P450 enzymes: interpretation of their interactions with selective serotonin reuptake inhibitors. Part II.

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12 December 2020

10.2165/00003088-200746040-00002

Identifiers

DOI

1 reference

PubMed ID

17375980

Dimensions Publication ID

3 August 2017

0 references

1 reference

PubMed ID

17375980