(Q34611156)

3 August 2017

Modeling endotoxin-induced systemic inflammation using an indirect response approach (English)

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3 August 2017

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systemic inflammation

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P T Foteinou

1

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3 August 2017

S E Calvano

series ordinal

2

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3 August 2017

S F Lowry

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3

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3 August 2017

I P Androulakis

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4

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3 August 2017

20 September 2008

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3 August 2017

16

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inferred from page(s)

published in

Mathematical Biosciences

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3 August 2017

217

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3 August 2017

1

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3 August 2017

27-42

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maintained by WikiProject

3 August 2017

WikiProject Mathematics

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cites work

Severe sepsis and septic shock: the role of gram-negative bacteremia

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Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C.

7 July 2018

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Optimization by Simulated Annealing

7 July 2018

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Strategies to modulate cellular energetic metabolism during sepsis.

7 July 2018

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The JAK-STAT signaling pathway: input and output integration

7 July 2018

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Meta-analysis of several gene lists for distinct types of cancer: a simple way to reveal common prognostic markers

7 July 2018

1 reference

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In silico and in vivo approach to elucidate the inflammatory complexity of CD14-deficient mice

7 July 2018

1 reference

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In silico models of acute inflammation in animals.

7 July 2018

1 reference

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Gene expression profiles of peripheral blood leukocytes after endotoxin challenge in humans

7 July 2018

1 reference

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Human endotoxemia: a model for mechanistic insight and therapeutic targeting

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Modeling of the bacterial growth curve

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Significance analysis of time course microarray experiments

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

A network-based analysis of systemic inflammation in humans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Application of genome-wide expression analysis to human health and disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Inflammation suppressor genes: please switch out all the lights

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Acute inflammatory response to endotoxin in mice and humans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Toll-like receptors in the pathogenesis of human disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

The dynamics of acute inflammation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Bench to bedside: HMGB1-a novel proinflammatory cytokine and potential therapeutic target for septic patients in the emergency department

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Molecular mechanisms of endotoxin tolerance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Expression profiling analysis of the metabolic and inflammatory changes following burn injury in rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Lipopolysaccharide-mediated signal transduction: Stabilization of TNF-alpha mRNA contributes to increased lipopolysaccharide-stimulated TNF-alpha production by Kupffer cells after chronic ethanol feeding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

A systems approach to dissecting immunity and inflammation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

A positive-feedback-based bistable 'memory module' that governs a cell fate decision

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

ArrayTrack--supporting toxicogenomic research at the U.S. Food and Drug Administration National Center for Toxicological Research

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Diversity of mechanism-based pharmacodynamic models

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

A new paradigm for the treatment of sepsis: is it time to consider combination therapy?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Measurement of endotoxin activity in critically ill patients using whole blood neutrophil dependent chemiluminescence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

LPS induction of gene expression in human monocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Pharmacokinetic/pharmacodynamic modeling in drug research and development.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Analysis of Tlr4-mediated LPS signal transduction in macrophages by mutational modification of the receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

HMG-1 as a late mediator of endotoxin lethality in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Molecular basis of endotoxin tolerance.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Characteristics of indirect pharmacodynamic models and applications to clinical drug responses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Mathematical formalism for the properties of four basic models of indirect pharmacodynamic responses.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Changes in endotoxin-induced cytokine production by whole blood after in vivo exposure of normal humans to endotoxin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Influence of IL-1 receptor blockade on the human response to endotoxemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Tolerance to endotoxin-induced expression of the interleukin-1 beta gene in blood neutrophils of humans with the sepsis syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

The role of endotoxin during typhoid fever and tularemia in man. IV. The integrity of the endotoxin tolerance mechanisms during infection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Prevention by polymyxin B of endotoxin lethality in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

The acute splanchnic and peripheral tissue metabolic response to endotoxin in humans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Experimental endotoxemia in humans: analysis of cytokine release and coagulation, fibrinolytic, and complement pathways.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Analysis of a lumped model for tissue inflammation dynamics.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

The role of initial trauma in the host's response to injury and hemorrhage: insights from a correlation of mathematical simulations and hepatic transcriptomic analysis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

A reduced mathematical model of the acute inflammatory response II. Capturing scenarios of repeated endotoxin administration.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

A reduced mathematical model of the acute inflammatory response: I. Derivation of model and analysis of anti-inflammation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Differential gene expression profiling in whole blood during acute systemic inflammation in lipopolysaccharide-treated rats.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Multiorgan failure is an adaptive, endocrine-mediated, metabolic response to overwhelming systemic inflammation.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Compartmentalization of tolerance to endotoxin.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Modeling of corticosteroid pharmacogenomics in rat liver using gene microarrays

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

Association between mitochondrial dysfunction and severity and outcome of septic shock

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045970

IL-12 Suppression During Experimental Endotoxin Tolerance: Dendritic Cell Loss and Macrophage Hyporesponsiveness

26 October 2018

1 reference

12 December 2020

Integrated functions for four basic models of indirect pharmacodynamic response

1 reference

12 December 2020

Kinetics of binding of LPS to recombinant CD14, TLR4, and MD-2 proteins

1 reference

12 December 2020

On the use of the Kolmogorov-Smirnov statistical test for immunofluorescence histogram comparison

1 reference

12 December 2020

Modulation of mouse endotoxin shock by inhibition of phosphatidylcholine-specific phospholipase C

1 reference

12 December 2020

Nicotine exposure alters in vivo human responses to endotoxin

1 reference

12 December 2020

Bioinformatics analysis of the early inflammatory response in a rat thermal injury model

1 reference

12 December 2020

The acute inflammatory response in diverse shock states

1 reference

12 December 2020

Septic shock without documented infection: an uncommon entity with a high mortality

1 reference

12 December 2020

Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma : a molecular basis for priming and synergism with bacterial lipopolysaccharide

1 reference

12 December 2020

Cell fates as high-dimensional attractor states of a complex gene regulatory network

1 reference

12 December 2020

10.1016/J.MBS.2008.09.003

Identifiers

DOI

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3 August 2017

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3 August 2017

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