(Q34611677)

3 August 2017

title

A GDI (AGS3) and a GEF (GIV) regulate autophagy by balancing G protein activity and growth factor signals (English)

1 reference

3 August 2017

0 references

3

Marilyn G Farquhar

1 reference

3 August 2017

Mikel Garcia-Marcos

1

1 reference

3 August 2017

Jason Ear

series ordinal

2

1 reference

3 August 2017

Pradipta Ghosh

series ordinal

4

1 reference

3 August 2017

publication date

5 January 2011

1 reference

Molecular Biology of the Cell

3 August 2017

published in

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3 August 2017

volume

22

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3 August 2017

issue

5

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3 August 2017

page(s)

673-686

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describes a project that uses

3 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3046063/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

A G{alpha}i-GIV molecular complex binds epidermal growth factor receptor and determines whether cells migrate or proliferate

1 reference

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A structural determinant that renders G alpha(i) sensitive to activation by GIV/girdin is required to promote cell migration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Biochemical isolation and characterization of the tubulovesicular LC3-positive autophagosomal compartment

7 July 2018

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7 July 2018

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Heterotrimeric G proteins and apoptosis: intersecting signaling pathways leading to context dependent phenotypes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

A non-canonical MEK/ERK signaling pathway regulates autophagy via regulating Beclin 1.

7 July 2018

1 reference

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Slit diaphragms contain tight junction proteins

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Galpha(i1) and Galpha(i3) are required for epidermal growth factor-mediated activation of the Akt-mTORC1 pathway

7 July 2018

1 reference

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GIV is a nonreceptor GEF for G alpha i with a unique motif that regulates Akt signaling

7 July 2018

1 reference

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The role of autophagy in mammalian development: cell makeover rather than cell death

7 July 2018

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Activation of Galphai3 triggers cell migration via regulation of GIV.

7 July 2018

1 reference

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Ric-8A catalyzes guanine nucleotide exchange on G alphai1 bound to the GPR/GoLoco exchange inhibitor AGS3.

7 July 2018

1 reference

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An actin-binding protein Girdin regulates the motility of breast cancer cells

7 July 2018

1 reference

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Regulation of VEGF-mediated angiogenesis by the Akt/PKB substrate Girdin.

7 July 2018

1 reference

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7 July 2018

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7 July 2018

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7 July 2018

1 reference

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An obligatory requirement for the heterotrimeric G protein Gi3 in the antiautophagic action of insulin in the liver

7 July 2018

1 reference

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Proteomics fingerprinting of phagosome maturation and evidence for the role of a Galpha during uptake

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome

7 July 2018

1 reference

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Targeted knockdown of G protein subunits selectively prevents receptor-mediated modulation of effectors and reveals complex changes in non-targeted signaling proteins

7 July 2018

1 reference

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Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Autophagy in metazoans: cell survival in the land of plenty

7 July 2018

1 reference

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7 July 2018

1 reference

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STRING: known and predicted protein-protein associations, integrated and transferred across organisms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Autophagy in health and disease: a double-edged sword

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Regulation and role of autophagy in mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Return of the GDI: the GoLoco motif in cell division.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Thermodynamic Characterization of the Binding of Activator of G Protein Signaling 3 (AGS3) and Peptides Derived from AGS3 with Gαi1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

The G-protein regulator AGS3 controls an early event during macroautophagy in human intestinal HT-29 cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

The phagosome proteome: insight into phagosome functions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Activator of G protein signaling 3 is a guanine dissociation inhibitor for Galpha i subunits

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Stabilization of the GDP-bound conformation of Gialpha by a peptide derived from the G-protein regulatory motif of AGS3.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Control of the expression and activity of the Galpha-interacting protein (GAIP) in human intestinal cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Guanine nucleotide exchange on heterotrimeric Gi3 protein controls autophagic sequestration in HT-29 cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

A heterotrimeric Gi3-protein controls autophagic sequestration in the human colon cancer cell line HT-29.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

G proteins: transducers of receptor-generated signals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

Monitoring autophagy in mammalian cultured cells through the dynamics of LC3.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

A systems biology analysis of the Drosophila phagosome

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3046063

26 October 2018

Identifiers

DOI

10.1091/MBC.E10-08-0738

1 reference

3 August 2017

1 reference

3 August 2017

1 reference