(Q34616057)

3 August 2017

title

The development of highly potent inhibitors for porcupine (English)

1 reference

3 August 2017

Chuo Chen

14

0 references

author name string

Xiaolei Wang

1

1 reference

3 August 2017

Jesung Moon

2

1 reference

3 August 2017

Michael E Dodge

3

1 reference

3 August 2017

Xinchao Pan

4

1 reference

3 August 2017

Lishu Zhang

5

1 reference

3 August 2017

Jordan M Hanson

6

1 reference

3 August 2017

Rubina Tuladhar

7

1 reference

3 August 2017

Zhiqiang Ma

8

1 reference

3 August 2017

Heping Shi

9

1 reference

3 August 2017

Noelle S Williams

10

1 reference

3 August 2017

James F Amatruda

11

1 reference

3 August 2017

Thomas J Carroll

12

1 reference

3 August 2017

Lawrence Lum

13

1 reference

3 August 2017

language of work or name

English

0 references

publication date

19 March 2013

1 reference

Journal of Medicinal Chemistry

3 August 2017

published in

1 reference

3 August 2017

volume

56

1 reference

3 August 2017

issue

6

1 reference

3 August 2017

page(s)

2700-2704

1 reference

Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer.

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631274

Cell biology. The unusual case of Porcupine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631274

Wnt/β-catenin signaling and disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631274

Diverse chemical scaffolds support direct inhibition of the membrane-bound O-acyltransferase porcupine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631274

Significant species difference in amide hydrolysis of GDC-0834, a novel potent and selective Bruton's tyrosine kinase inhibitor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631274

Genome-wide RNAi screen reveals disease-associated genes that are common to Hedgehog and Wnt signaling.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631274

Tankyrase is necessary for canonical Wnt signaling during kidney development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631274

Structure-activity relationship studies of small-molecule inhibitors of Wnt response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631274

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631274

Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631274

In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631274

Utility of the carboxylesterase inhibitor bis-para-nitrophenylphosphate (BNPP) in the plasma unbound fraction determination for a hydrolytically unstable amide derivative and agonist of the TGR5 receptor

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631274

Suppression of PPN/MG61 attenuates Wnt/beta-catenin signaling pathway and induces apoptosis in human lung cancer.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3631274

Esterase activities in the blood, liver and intestine of several preclinical species and humans

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23477365

12 December 2020

inferred from PubMed ID database lookup

Comparative analysis of esterase activities of human, mouse, and rat blood

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23477365

12 December 2020

inferred from PubMed ID database lookup

Species difference of esterase expression and hydrolase activity in plasma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23477365

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1021/JM400159C

1 reference

release_rkgwgwjmyjb7fp3axaln3w62oq

3 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/rkgwgwjmyjb7fp3axaln3w62oq

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3631274

1 reference

3 August 2017

1 reference