(Q34621367)

3 August 2017

title

Towards microfluidic technology-based MALDI-MS platforms for drug discovery: a review (English)

1 reference

matrix-assisted laser desorption/ionization

3 August 2017

main subject

0 references

0 references

1 reference

Sanjiv Sharma

4

0 references

author name string

Richard F Winkle

series ordinal

1

1 reference

3 August 2017

Judit M Nagy

series ordinal

2

1 reference

3 August 2017

Anthony Eg Cass

series ordinal

3

1 reference

3 August 2017

language of work or name

English

0 references

publication date

1 November 2008

1 reference

Expert Opinion on Drug Discovery

3 August 2017

number of pages

12

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

3 August 2017

volume

3

1 reference

3 August 2017

issue

11

1 reference

3 August 2017

page(s)

1281-1292

1 reference

High-throughput screening for kinase inhibitors

3 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Micro total analysis systems. 2. Analytical standard operations and applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Micro total analysis systems. Recent developments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

A rapid diffusion immunoassay in a T-sensor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Gold nanoparticle assembly microfluidic reactor for efficient on-line proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Label-free microelectronic PCR quantification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Microchip device for performing enzyme assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Development of a multichannel microfluidic analysis system employing affinity capillary electrophoresis for immunoassay

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Fabrication of phospholipid bilayer-coated microchannels for on-chip immunoassays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Capacitance cytometry: measuring biological cells one by one.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

An integrated microfluidics-tandem mass spectrometry system for automated protein analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

A microfluidic cartridge to prepare spores for PCR analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Integrated system for rapid PCR-based DNA analysis in microfluidic devices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Single-molecule DNA amplification and analysis in an integrated microfluidic device

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Dynamic DNA hybridization on a chip using paramagnetic beads.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Eight hundred-base sequencing in a microfabricated electrophoretic device.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Cell separation on microfabricated electrodes using dielectrophoretic/gravitational field-flow fractionation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Long-term monitoring of bacteria undergoing programmed population control in a microchemostat

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Combinatorial compound libraries for drug discovery: an ongoing challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Lab-on-a-chip: microfluidics in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Glass microchip with three-dimensional microchannel network for 2 x 2 parallel synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Synthesis and analysis of combinatorial libraries performed in an automated micro reactor system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Experimental test of scaling of mixing by chaotic advection in droplets moving through microfluidic channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

A microfluidic system for controlling reaction networks in time

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Formation of droplets of alternating composition in microfluidic channels and applications to indexing of concentrations in droplet-based assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Millisecond Kinetics on a Microfluidic Chip Using Nanoliters of Reagents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Man-made cell-like compartments for molecular evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

High-throughput screens and selections of enzyme-encoding genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Controlled microfluidic encapsulation of cells, proteins, and microbeads in lipid vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Selective encapsulation of single cells and subcellular organelles into picoliter- and femtoliter-volume droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Chemical transformations in individual ultrasmall biomimetic containers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

The genesis of high-throughput structure-based drug discovery using protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Solvent resistant microfluidic DNA synthesizer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Microreactor microfluidic systems with human microsomes and hepatocytes for use in metabolite studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

MALDI-TOF MS as a label-free approach to rapid inhibitor screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Mass spectrometry for enzyme assays and inhibitor screening: an emerging application in pharmaceutical research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Affinity selection-mass spectrometry screening techniques for small molecule drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

High-throughput mass spectrometry screening for inhibitors of phosphatidylserine decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Immunoassays with direct mass spectrometric detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Identification of protein ligands in complex biological samples using intensity-fading MALDI-TOF mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Functional screening of serine protease inhibitors in the medical leech Hirudo medicinalis monitored by intensity fading MALDI-TOF MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Imaging mass spectrometry: a new technology for the analysis of protein expression in mammalian tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Processing MALDI Mass Spectra to Improve Mass Spectral Direct Tissue Analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Imaging mass spectrometry: fundamentals and applications to drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Sensitivity and mass accuracy for proteins analyzed directly from polyacrylamide gels: implications for proteome mapping.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

A high pressure matrix-assisted laser desorption ion source for Fourier transform mass spectrometry designed to accommodate large targets with diverse surfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Coupling thin-layer chromatography with vibrational cooling matrix-assisted laser desorption/ionization Fourier transform mass spectrometry for the analysis of ganglioside mixtures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Analysis of gangliosides directly from thin-layer chromatography plates by infrared matrix-assisted laser desorption/ionization orthogonal time-of-flight mass spectrometry with a glycerol matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Infrared laser desorption and ionization of polypeptides from a polyacrylamide gel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

DNA sequencing using capillary array electrophoresis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Microfluidics for multiplexed MS analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Microfabricated devices: A new sample introduction approach to mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Microfluidic technologies for MALDI-MS in proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Proteome-on-a-chip: mirage, or on the horizon?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Electrospray interfacing of polymer microfluidics to MALDI-MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Electrophoresis separation in open microchannels. A method for coupling electrophoresis with MALDI-MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Autonomous protein sample processing on-chip using solid-phase microextraction, capillary force pumping, and microdispensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Integrated sample preparation and MALDI mass spectrometry on a microfluidic compact disk

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Electrowetting-based microfluidics for analysis of peptides and proteins by matrix-assisted laser desorption/ionization mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Digital microfluidics with in-line sample purification for proteomics analyses with MALDI-MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Integrated microfluidic system enabling (bio)chemical reactions with on-line MALDI-TOF mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

A MALDI-chip integrated system with a monitoring window

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Direct coupling of polymer-based microchip electrophoresis to online MALDI-MS using a rotating ball inlet

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Interfacing capillary gel microfluidic chips with infrared laser desorption mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

An integrated microfluidic chip for the analysis of biochemical reactions by MALDI mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Polymeric integrated selective enrichment target (ISET) for solid-phase-based sample preparation in MALDI-TOF MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

Development of an automated digestion and droplet deposition microfluidic chip for MALDI-TOF MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.11.1281

10.1517/17460441.3.11.1281

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference