(Q34626953)

3 August 2017

The why and how of phenotypic small-molecule screens (English)

1 reference

3 August 2017

Ulrike S Eggert

1

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publication date

1 April 2013

1 reference

3 August 2017

Nature Chemical Biology

1 reference

3 August 2017

9

1 reference

3 August 2017

4

1 reference

3 August 2017

206-209

1 reference

https://scigraph.springernature.com/pub.10.1038/nchembio.1206

3 August 2017

0 references

cites work

How were new medicines discovered?

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Small molecule probes of cellular pathways and networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Target profiling of small molecules by chemical proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Searching for the protein targets of bioactive molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Identifying mechanism-of-action targets for drugs and probes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Target identification and mechanism of action in chemical biology and drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Small molecules in an RNAi world

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Dynasore, a cell-permeable inhibitor of dynamin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Dopamine receptor D3 regulates endocytic sorting by a Prazosin-sensitive interaction with the coatomer COPI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Brefeldin A's effects on endosomes, lysosomes, and the TGN suggest a general mechanism for regulating organelle structure and membrane traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin A suggests an ER recycling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: evidence for membrane cycling from Golgi to ER

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Brefeldin A acts to stabilize an abortive ARF-GDP-Sec7 domain protein complex: involvement of specific residues of the Sec7 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Structural basis for the inhibitory effect of brefeldin A on guanine nucleotide-exchange proteins for ADP-ribosylation factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

The art of the chemical probe

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Colloidal aggregation affects the efficacy of anticancer drugs in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Open access chemical and clinical probes to support drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

21 January 2018

Too many roads not taken

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Antiviral activity of brefeldin A and verrucarin A.

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

21 January 2018

https://pubmed.ncbi.nlm.nih.gov/23508174

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1206

21 January 2018

Identifiers

DOI

10.1038/NCHEMBIO.1206

1 reference

3 August 2017

1 reference

PubMed ID

23508174