(Q34627230)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21354971%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway (English)

1 reference

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23 January 2020

0 references

16

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23 January 2020

18

Ralf Gold

1 reference

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23 January 2020

author name string

Ralf A Linker

1

1 reference

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23 January 2020

De-Hyung Lee

2

1 reference

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23 January 2020

Sarah Ryan

3

1 reference

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23 January 2020

Anne M van Dam

4

1 reference

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23 January 2020

Rebecca Conrad

5

1 reference

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23 January 2020

Pradeep Bista

6

1 reference

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23 January 2020

Weike Zeng

7

1 reference

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23 January 2020

Xiaoping Hronowsky

8

1 reference

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23 January 2020

Alex Buko

9

1 reference

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23 January 2020

Sowmya Chollate

10

1 reference

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23 January 2020

Gisa Ellrichmann

11

1 reference

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23 January 2020

Wolfgang Brück

12

1 reference

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23 January 2020

Kate Dawson

13

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23 January 2020

Susan Goelz

14

1 reference

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23 January 2020

Stefan Wiese

15

1 reference

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23 January 2020

Matvey Lukashev

17

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23 January 2020

language of work or name

English

0 references

publication date

1 March 2011

1 reference

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23 January 2020

1 reference

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23 January 2020

volume

134

1 reference

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23 January 2020

issue

Pt 3

1 reference

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23 January 2020

page(s)

678-692

1 reference

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Green tea epigallocatechin-3-gallate mediates T cellular NF-kappa B inhibition and exerts neuroprotection in autoimmune encephalomyelitis

23 January 2020

cites work

1 reference

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Neuronal damage in autoimmune neuroinflammation mediated by the death ligand TRAIL.

21 January 2018

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Axonal protection using flecainide in experimental autoimmune encephalomyelitis.

21 January 2018

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TASK1 modulates inflammation and neurodegeneration in autoimmune inflammation of the central nervous system

21 January 2018

1 reference

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Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Sulforaphane protects astrocytes against oxidative stress and delayed death caused by oxygen and glucose deprivation

21 January 2018

1 reference

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Selective stimulation of T helper 2 cytokine responses by the anti-psoriasis agent monomethylfumarate

21 January 2018

1 reference

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Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research.

21 January 2018

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Vacuolar leukoencephalopathy with widespread astrogliosis in mice lacking transcription factor Nrf2

21 January 2018

1 reference

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 January 2018

1 reference

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The absence of the pro-antioxidant transcription factor Nrf2 exacerbates experimental autoimmune encephalomyelitis

21 January 2018

1 reference

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Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

21 January 2018

1 reference

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Chitosan prevents oxidative stress-induced amyloid beta formation and cytotoxicity in NT2 neurons: involvement of transcription factors Nrf2 and NF-kappaB.

21 January 2018

1 reference

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Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Cytoprotective effects of lindenenyl acetate isolated from Lindera strychnifolia on mouse hippocampal HT22 cells

21 January 2018

1 reference

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Identification and development of new therapeutics for multiple sclerosis

21 January 2018

1 reference

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Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis

21 January 2018

1 reference

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Fumarates for the treatment of multiple sclerosis: potential mechanisms of action and clinical studies

21 January 2018

1 reference

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Monomethylfumarate affects polarization of monocyte-derived dendritic cells resulting in down-regulated Th1 lymphocyte responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

A genomic screen for activators of the antioxidant response element

21 January 2018

1 reference

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Dimethylfumarate inhibits TNF-induced nuclear entry of NF-kappa B/p65 in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

The carboxy-terminal Neh3 domain of Nrf2 is required for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Direct measurement of NAD(P)H:quinone reductase from cells cultured in microtiter wells: A screening assay for anticarcinogenic enzyme inducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Simple ortho- and para-hydroquinones as compounds neuroprotective against oxidative stress in a manner associated with specific transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Oral fumaric acid esters for the treatment of active multiple sclerosis: an open-label, baseline-controlled pilot study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Reactivity of dimethyl fumarate and methylhydrogen fumarate towards glutathione and N-acetyl-L-cysteine--preparation of S-substituted thiosuccinic acid esters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo.

21 January 2018

1 reference

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A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Reduction of H2O2-evoked, intracellular calcium increases in the rat N18-RE-105 neuronal cell line by pretreatment with an electrophilic antioxidant inducer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Fumaric acid dialkyl esters deprive cultured rat oligodendroglial cells of glutathione and upregulate the expression of heme oxygenase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Dimethylfumarate is a potent inducer of apoptosis in human T cells

21 January 2018

1 reference

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L-Dopa stimulates expression of the antioxidant enzyme NAD(P)H:quinone oxidoreductase (NQO) in cultured astroglial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ386

Nrf2 and DJ1 are consistently upregulated in inflammatory multiple sclerosis lesions.

21 January 2018

1 reference

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Dimethylfumarate is an inhibitor of cytokine-induced E-selectin, VCAM-1, and ICAM-1 expression in human endothelial cells.

21 January 2018

1 reference

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Detoxication enzyme inducers modify cytokine production in rat mixed glial cells

21 January 2018

1 reference

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Axon loss in the spinal cord determines permanent neurological disability in an animal model of multiple sclerosis.

21 January 2018

1 reference

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Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription.

21 January 2018

1 reference

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Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: Implications for multiple sclerosis

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1093/BRAIN/AWQ386

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21354971%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference