(Q34627237)

3 August 2017

title

In vitro and in vivo antiplasmodial activities of risedronate and its interference with protein prenylation in Plasmodium falciparum (English)

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3 August 2017

main subject

Plasmodium falciparum

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author

Alejandro M Katzin

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ORCID Public Data File 2021

Danilo C Miguel

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ORCID Public Data File 2021

author name string

Fabiana Morandi Jordão

1

1 reference

3 August 2017

Alexandre Yukio Saito

2

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3 August 2017

Danilo Ciccone Miguel

3

1 reference

3 August 2017

Valnice de Jesus Peres

4

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3 August 2017

Emília Akemi Kimura

5

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3 August 2017

Alejandro Miguel Katzin

6

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3 August 2017

language of work or name

English

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publication date

28 February 2011

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Antimicrobial Agents and Chemotherapy

3 August 2017

published in

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3 August 2017

volume

55

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3 August 2017

issue

5

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3 August 2017

page(s)

2026-2031

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Molecular Characterization of a Novel Geranylgeranyl Pyrophosphate Synthase from Plasmodium Parasites

3 August 2017

cites work

1 reference

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Limonene arrests parasite development and inhibits isoprenylation of proteins in Plasmodium falciparum.

7 July 2018

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Protein geranylgeranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphonates and GGTI-298.

7 July 2018

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7 July 2018

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Active isoprenoid pathway in the intra-erythrocytic stages of Plasmodium falciparum: presence of dolichols of 11 and 12 isoprene units

7 July 2018

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Protein prenyl transferase activities of Plasmodium falciparum

7 July 2018

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7 July 2018

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Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

7 July 2018

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7 July 2018

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Regulation of the mevalonate pathway

7 July 2018

1 reference

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Protein isoprenylation and methylation at carboxyl-terminal cysteine residues

7 July 2018

1 reference

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Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A

7 July 2018

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Human malaria parasites in continuous culture

7 July 2018

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7 July 2018

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Efficacy, tolerability, and safety of risedronate in Japanese patients with Paget's disease of bone

7 July 2018

1 reference

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Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase.

26 October 2018

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The farnesyl-diphosphate/geranylgeranyl-diphosphate synthase of Toxoplasma gondii is a bifunctional enzyme and a molecular target of bisphosphonates

26 October 2018

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Risedronate in the treatment of Murine Chagas' disease

26 October 2018

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Radical cure of experimental cutaneous leishmaniasis by the bisphosphonate pamidronate

26 October 2018

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The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate: evidence for the formation in vivo of a metabolite that inhibits bone resorption and causes osteoclast and macrophage apoptosis

26 October 2018

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Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088194

Trypanosoma cruzi contains major pyrophosphate stores, and its growth in vitro and in vivo is blocked by pyrophosphate analogs

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088194

Phosphonate and bisphosphonate analogues of farnesyl pyrophosphate as potential inhibitors of farnesyl protein transferase

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088194

N-linked glycoproteins are related to schizogony of the intraerythrocytic stage in Plasmodium falciparum

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088194

Isoprenylation of proteins in the protozoan Giardia lamblia

26 October 2018

1 reference

12 December 2020

Identification and characterisation of Toxoplasma gondii protein farnesyltransferase

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12 December 2020

Mechanisms of action of bisphosphonates

1 reference

12 December 2020

Characterisation of protein isoprenylation in procyclic form Trypanosoma brucei

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12 December 2020

Bisphosphonates in cancer therapy

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12 December 2020

Identifiers

DOI

10.1128/AAC.01820-10

1 reference

3 August 2017

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3 August 2017

1 reference