(Q34632490)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

0 references

0 references

1

1 reference

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16 February 2020

Sunia A Trauger

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Jack P. Antel

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

15

Howard L Weiner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Francisco J. Quintana

16

object named as

Francisco J Quintana

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

13

Alexandre Prat

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

11

Benjamin Ellezam

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Manon Blain

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Meghan Nadeau

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Bonny Patel

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Jorge I Alvarez

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Ivan D Mascanfroni

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Ada Yeste

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Pia Kivisäkk

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Keith Kallas

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Rohit Bakshi

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

language of work or name

English

0 references

publication date

14 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

number of pages

10

1 reference

inferred from page(s)

published in

Nature Medicine

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

20

1 reference

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16 February 2020

issue

10

1 reference

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16 February 2020

page(s)

1147-1156

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

β4GalT6 is involved in the synthesis of lactosylceramide with less intensity than β4GalT5.

16 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Lactosylceramide interacts with and activates cytosolic phospholipase A2α.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Emerging roles of astrocytes in neural circuit development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Regional astrocyte allocation regulates CNS synaptogenesis and repair.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

The innate immune system in demyelinating disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Lipids and lipid-reactive antibodies as biomarkers for multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Lactosylceramide Mediates the Expression of Adhesion Molecules in TNF-α and IFNγ-stimulated Primary Cultured Astrocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Transcriptional regulation of macrophage polarization: enabling diversity with identity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Protective and pathogenic functions of macrophage subsets

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Repertoire of microglial and macrophage responses after spinal cord injury

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Reactive astrocytes form scar-like perivascular barriers to leukocytes during adaptive immune inflammation of the CNS.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

The challenge of multiple sclerosis: how do we cure a chronic heterogeneous disease?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Distinct stages of myelination regulated by gamma-secretase and astrocytes in a rapidly myelinating CNS coculture system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Resolvin E1 and protectin D1 activate inflammation-resolution programmes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Astrocyte dysfunction in neurological disorders: a molecular perspective

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Lactosylceramide recruits PKCalpha/epsilon and phospholipase A2 to stimulate PECAM-1 expression in human monocytes and adhesion to endothelial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Inhibition of reactive astrocytosis in established experimental autoimmune encephalomyelitis favors infiltration by myeloid cells over T cells and enhances severity of disease.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Beta4-galactosyltransferase-5 is a lactosylceramide synthase essential for mouse extra-embryonic development

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Astroglial metabolic networks sustain hippocampal synaptic transmission

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Essential protective roles of reactive astrocytes in traumatic brain injury

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Lipid microarrays identify key mediators of autoimmune brain inflammation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Experimental autoimmune encephalomyelitis repressed by microglial paralysis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4255949

IL-17 silencing does not protect nonobese diabetic mice from autoimmune diabetes

26 October 2018

1 reference

PubMed

12 December 2020

Lactosylceramide synthase as a therapeutic target to mitigate multiple human diseases in animal models

1 reference

PubMed

12 December 2020

1 reference

12 December 2020

GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitis

1 reference

PubMed

12 December 2020

GFAP promoter-controlled EGFP-expressing transgenic mice: a tool to visualize astrocytes and astrogliosis in living brain tissue

1 reference

7 January 2021

Isolation of murine microglial cells for RNA analysis or flow cytometry

1 reference

7 January 2021

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

1 reference

7 January 2021

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

1 reference

7 January 2021

Genomic analysis of reactive astrogliosis

1 reference

7 January 2021

Expander: from expression microarrays to networks and functions

1 reference

7 January 2021

High-yield isolation of murine microglia by mild trypsinization.

1 reference

7 January 2021

IFN-γ-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair

1 reference

7 January 2021

Derivation of primary choroid plexus epithelial cells from the mouse.

1 reference

7 January 2021

TLR signaling tailors innate immune responses in human microglia and astrocytes

1 reference

7 January 2021

The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM.3681

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

25216636

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25216636%20AND%20SRC:MED&resulttype=core&format=json