(Q34633750)

3 August 2017

Multiple signal pathways in obesity-associated cancer (English)

1 reference

3 August 2017

0 references

J Chen

1

1 reference

3 August 2017

22 August 2011

1 reference

3 August 2017

1 reference

3 August 2017

12

1 reference

3 August 2017

12

1 reference

3 August 2017

1063-1070

1 reference

Obesity and post-operative complications in patients undergoing non-bariatric surgery.

3 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Associations between adipokines and obesity-related cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Obesity and gastrointestinal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Obesity Increases the Risk of Postmenopausal Breast Cancer and is Associated with More Advanced Stage at Presentation But no Impact on Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Obesity is an independent prognostic variable in colon cancer survivors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Body-mass index and cancer mortality in the Asia-Pacific Cohort Studies Collaboration: pooled analyses of 424,519 participants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

High susceptibility to azoxymethane-induced colorectal carcinogenesis in obese KK-Ay mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Diet-induced obesity accelerates acute lymphoblastic leukemia progression in two murine models

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Insulin-like growth factor-I regulates the liver microenvironment in obese mice and promotes liver metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Dietary energy balance modulates signaling through the Akt/mammalian target of rapamycin pathways in multiple epithelial tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Obesity, the PI3K/Akt signal pathway and colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Associations between leptin and adiponectin receptor upregulation, visceral obesity and tumour stage in oesophageal and junctional adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Insulin and insulin-like growth factor signalling in neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Growth hormone, the insulin-like growth factor axis, insulin and cancer risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Obesity predisposes to Th17 bias

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Subcellular localization of cyclic AMP-responsive element binding protein-regulated transcription coactivator 2 provides a link between obesity and breast cancer in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

STATs in cancer inflammation and immunity: a leading role for STAT3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Targeting the mitogen-activated protein kinase cascade to treat cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

The role of MAP kinases and MAP kinase phosphatase-1 in resistance to breast cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

New strategies in colorectal cancer: biomarkers of response to epidermal growth factor receptor monoclonal antibodies and potential therapeutic targets in phosphoinositide 3-kinase and mitogen-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Tumours with PI3K activation are resistant to dietary restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Targeting the phosphoinositide 3-kinase pathway in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Signal integration by JNK and p38 MAPK pathways in cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Inhibitors of phosphatidylinositol-3-kinase in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Role of the PI3K/AKT and mTOR signaling pathways in acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

The PI3K-Akt mediates oncogenic Met-induced centrosome amplification and chromosome instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Lack of PTEN sequesters CHK1 and initiates genetic instability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

MAPK signaling in inflammation-associated cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Mechanisms of drug inhibition of signalling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Targeting the MAPK pathway in melanoma: why some approaches succeed and other fail

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Pharmacological inhibitors of MAPK pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

21 January 2018

Insulin and colon cancer

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Insulin, insulin-like growth factor-I, endogenous estradiol, and risk of colorectal cancer in postmenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Endocrine disruptors induce cytochrome P450 by affecting transcriptional regulation via pregnane X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Obesity provides a permissive milieu in inflammation-associated carcinogenesis: analysis of insulin and IGF pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Insulin-mediated acceleration of breast cancer development and progression in a nonobese model of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Reduced susceptibility to two-stage skin carcinogenesis in mice with low circulating insulin-like growth factor I levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Genetic reduction of circulating insulin-like growth factor-1 inhibits azoxymethane-induced colon tumorigenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Ten years of leptin replacement therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Leptin and gastro-intestinal malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Leptin induces functional activation of cyclooxygenase-2 through JAK2/STAT3, MAPK/ERK, and PI3K/AKT pathways in human endometrial cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Leptin promotes motility and invasiveness in human colon cancer cells by activating multiple signal-transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Adiponectin modulates C-jun N-terminal kinase and mammalian target of rapamycin and inhibits hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

IL-6 trans-signaling in formation and progression of malignant ascites in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

IL-6 is required for glioma development in a mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Interleukin-6 in bone metastasis and cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

The possible role of IL-17 in obesity-associated cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Leptin deficiency-induced obesity exacerbates ultraviolet B radiation-induced cyclooxygenase-2 expression and cell survival signals in ultraviolet B-irradiated mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Preventive effects of (-)-epigallocatechin gallate on diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BL/KsJ-db/db Mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Activation of a metabolic gene regulatory network downstream of mTOR complex 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Involvement of JNK pathway in the promotion of the early stage of colorectal carcinogenesis under high-fat dietary conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Obesity increases the risk of UV radiation-induced oxidative stress and activation of MAPK and NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Epac1-induced cellular proliferation in prostate cancer cells is mediated by B-Raf/ERK and mTOR signaling cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Enhancing mammalian target of rapamycin (mTOR)-targeted cancer therapy by preventing mTOR/raptor inhibition-initiated, mTOR/rictor-independent Akt activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Overcoming mTOR inhibition-induced paradoxical activation of survival signaling pathways enhances mTOR inhibitors' anticancer efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

The PI3K pathway as drug target in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Vertical targeting of the phosphatidylinositol-3 kinase pathway as a strategy for treating melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

The dual PI3K/mTOR inhibitor, NVP-BEZ235, is efficacious against follicular lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Dual inhibition of PI3K and mTORC1/2 signaling by NVP-BEZ235 as a new therapeutic strategy for acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

NVP-BEZ235 as a new therapeutic option for sarcomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Dual targeting of phosphoinositide 3-kinase and mammalian target of rapamycin using NVP-BEZ235 as a novel therapeutic approach in human ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

Obesity and cancer in Asia-Pacific populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1467-789X.2011.00917.X

10.1111/J.1467-789X.2011.00917.X

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

22093240