(Q34635467)

3 August 2017

1 reference

title

The role of melanocortins in body weight regulation: opportunities for the treatment of obesity. (English)

1 reference

3 August 2017

0 references

17

Euan D MacIntyre

1 reference

3 August 2017

9

Alison M Strack

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3 August 2017

4

Tung M Fong

1 reference

3 August 2017

5

Ravi P Nargund

1 reference

3 August 2017

Douglas J MacNeil

1

1 reference

3 August 2017

Andrew D Howard

2

1 reference

3 August 2017

Xiaoming Guan

3

1 reference

3 August 2017

Maria A Bednarek

6

1 reference

3 August 2017

Mark T Goulet

7

1 reference

3 August 2017

David H Weinberg

8

1 reference

3 August 2017

Donald J Marsh

10

1 reference

3 August 2017

Howard Y Chen

11

1 reference

3 August 2017

Chun-Pyn Shen

12

1 reference

3 August 2017

Airu S Chen

13

1 reference

3 August 2017

Charles I Rosenblum

14

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3 August 2017

Tanya MacNeil

15

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3 August 2017

Michael Tota

16

1 reference

3 August 2017

Lex H T Van der Ploeg

18

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3 August 2017

language of work or name

English

0 references

publication date

1 April 2002

1 reference

European Journal of Pharmacology

3 August 2017

published in

1 reference

3 August 2017

volume

440

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3 August 2017

issue

2-3

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3 August 2017

page(s)

141-157

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Melanocortins and the brain: from effects via receptors to drug targets

3 August 2017

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Characterization of melanocortin receptor ligands on cloned brain melanocortin receptors and on grooming behavior in the rat

7 January 2021

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Expression of the melanocortin 5 receptor on rat lymphocytes

7 January 2021

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Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics

7 January 2021

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ACTH- and alpha-MSH-induced grooming, stretching, yawning and penile erection in male rats: site of action in the brain and role of melanocortin receptors

7 January 2021

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Anatomy of an endogenous antagonist: relationship between Agouti-related protein and proopiomelanocortin in brain.

7 January 2021

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Biochemical and genetic studies of pigment-type switching.

7 January 2021

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Selective, high affinity peptide antagonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro

7 January 2021

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Potent and selective peptide agonists of alpha-melanotropin action at human melanocortin receptor 4: their synthesis and biological evaluation in vitro.

7 January 2021

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A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences.

7 January 2021

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A combinatorial approach toward the discovery of non-peptide, subtype-selective somatostatin receptor ligands

7 January 2021

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7 January 2021

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Characterization of melanocortin receptor subtype expression in murine adipose tissues and in the 3T3-L1 cell line

7 January 2021

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Subtypes Y1 and Y2 of the neuropeptide Y receptor are respectively expressed in pro-opiomelanocortin- and neuropeptide-Y-containing neurons of the rat hypothalamic arcuate nucleus.

7 January 2021

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Changes in neuropeptide Y receptors and pro-opiomelanocortin in the anorexia (anx/anx) mouse hypothalamus.

7 January 2021

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Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat.

7 January 2021

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Linkage and association studies between the melanocortin receptors 4 and 5 genes and obesity-related phenotypes in the Québec Family Study

7 January 2021

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Enhanced expression of melanocortin-1 receptor (MC1-R) in normal human keratinocytes during differentiation: evidence for increased expression of POMC peptides near suprabasal layer of epidermis

7 January 2021

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Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides

7 January 2021

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Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass

7 January 2021

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Role of the melanocortin-4 receptor in metabolic rate and food intake in mice

7 January 2021

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Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA.

7 January 2021

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Molecular cloning of a novel human melanocortin receptor

7 January 2021

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In vitro and in vivo analysis of the processing and fate of the peptide products of the short proopiomelanocortin mRNA.

7 January 2021

1 reference

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Haplosufficiency of the melancortin-4 receptor gene in individuals with deletions of 18q

7 January 2021

1 reference

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A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

7 January 2021

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The Central Melanocortin System and Energy Homeostasis

7 January 2021

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Cyclic GMP phosphodiesterase-5: target of sildenafil

7 January 2021

1 reference

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Integration of NPY, AGRP, and melanocortin signals in the hypothalamic paraventricular nucleus: evidence of a cellular basis for the adipostat

7 January 2021

1 reference

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Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

7 January 2021

1 reference

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Neuropeptide Y innervation of ACTH-immunoreactive neurons in the arcuate nucleus of rats: a correlated light and electron microscopic double immunolabeling study

7 January 2021

1 reference

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Molecular screening of the proopiomelanocortin (POMC ) gene in Italian obese children: report of three new mutations

7 January 2021

1 reference

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Linkage and association studies between the proopiomelanocortin (POMC) gene and obesity in caucasian families

7 January 2021

1 reference

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Mutational analysis of melanocortin-4 receptor, agouti-related protein, and α-melanocyte-stimulating hormone genes in severely obese children

7 January 2021

1 reference

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Mutational analysis of the proopiomelanocortin gene in Caucasians with early onset obesity

7 January 2021

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Leptin activates hypothalamic CART neurons projecting to the spinal cord.

7 January 2021

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Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area.

7 January 2021

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Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists

7 January 2021

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Role of melanocortinergic neurons in feeding and the agouti obesity syndrome

7 January 2021

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The central melanocortin system can directly regulate serum insulin levels

7 January 2021

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Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency

7 January 2021

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Cloning, expression, and tissue distribution of a fifth melanocortin receptor subtype

7 January 2021

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A melanocortin agonist reduces neuronal firing rate in rat hypothalamic slices

7 January 2021

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ART (protein product of agouti-related transcript) as an antagonist of MC-3 and MC-4 receptors

7 January 2021

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NPY Y1 receptor like immunoreactivity exists in a subpopulation of beta-endorphin immunoreactive nerve cells in the arcuate nucleus: a double immunolabelling analysis in the rat.

7 January 2021

1 reference

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Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group

7 January 2021

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Molecular cloning and characterization of the rat fifth melanocortin receptor

7 January 2021

1 reference

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Brainstem application of melanocortin receptor ligands produces long-lasting effects on feeding and body weight.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Identification and functional analysis of novel human melanocortin-4 receptor variants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Mahogany/attractin: en route from phenotype to function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Leptin receptor immunoreactivity in chemically defined target neurons of the hypothalamus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Structure activity studies of the melanocortin-4 receptor by in vitro mutagenesis: identification of agouti-related protein (AGRP), melanocortin agonist and synthetic peptide antagonist interaction determinants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Beta-endorphin: cytokine and neuropeptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Systematic Mutation Screening of the Pro-Opiomelanocortin Gene: Identification of Several Genetic Variants Including Three Different Insertions, One Nonsense and Two Missense Point Mutations in Probands of Different Weight Extremes

7 January 2021

1 reference

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Several Mutations in the Melanocortin-4 Receptor Gene Including a Nonsense and a Frameshift Mutation Associated with Dominantly Inherited Obesity in Humans

7 January 2021

1 reference

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Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin recep

7 January 2021

1 reference

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Species-dependent pharmacological properties of the melanocortin-5 receptor

7 January 2021

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Targeted disruption of the melanocortin-4 receptor results in obesity in mice

7 January 2021

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alpha-Melanocyte stimulating hormone: immunohistochemical identification and mapping in neurons of rat brain

7 January 2021

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Unusual proopiomelanocortin ribonucleic acids in extrapituitary tissues: intronless transcripts in testes and long poly(A) tails in hypothalamus

7 January 2021

1 reference

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Melanocortin-3 receptor mRNA expression in pro-opiomelanocortin neurones of the rat arcuate nucleus

7 January 2021

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Immunocytochemical localization of ACTH perikarya in nucleus tractus solitarius: evidence for a second opiocortin neuronal system

7 January 2021

1 reference

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Evidence that orexigenic effects of melanocortin 4 receptor antagonist HS014 are mediated by neuropeptide Y.

7 January 2021

1 reference

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Melanocortin receptor binding determinants in the agouti protein

7 January 2021

1 reference

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Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone

7 January 2021

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The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin

7 January 2021

1 reference

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Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

7 January 2021

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Attractin/mahogany/zitter plays a critical role in myelination of the central nervous system

7 January 2021

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Molecular cloning of a mouse melanocortin 5 receptor gene widely expressed in peripheral tissues.

7 January 2021

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Melanocortin 3 receptor (MC3R) gene variants in extremely obese women

7 January 2021

1 reference

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Autoradiographic discrimination of melanocortin receptors indicates that the MC3 subtype dominates in the medial rat brain

7 January 2021

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Molecular mechanisms of beta-endorphin biosynthesis

7 January 2021

1 reference

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Detection of melanocortin-3 receptor mRNA in immature rat pituitary: functional relation to gamma3-MSH-induced changes in intracellular Ca2+ concentration?

7 January 2021

1 reference

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Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

7 January 2021

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Time course of short-term and long-term orexigenic effects of Agouti-related protein (86-132).

7 January 2021

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7 January 2021

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Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides.

7 January 2021

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Melanocortin-4 receptor mRNA expression in the developing autonomic and central nervous systems

7 January 2021

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Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain

7 January 2021

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Melanocortin mediated inhibition of feeding behavior in rats

7 January 2021

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The mahogany protein is a receptor involved in suppression of obesity

7 January 2021

1 reference

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AgRP(83-132) acts as an inverse agonist on the human-melanocortin-4 receptor

7 January 2021

1 reference

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Absence of genetic variation in some obesity candidate genes (GLP1R, ASIP, MC4R, MC5R) among Pima indians

7 January 2021

1 reference

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Central melanocortin receptors regulate insulin action

7 January 2021

1 reference

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Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein

7 January 2021

1 reference

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Design and biological activities of L-163,191 (MK-0677): a potent, orally active growth hormone secretagogue

7 January 2021

1 reference

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Expression of the pro-opiomelanocortin gene in dorsal root ganglia, spinal cord and sciatic nerve after sciatic nerve crush in the rat

7 January 2021

1 reference

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Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.

7 January 2021

1 reference

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Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system

7 January 2021

1 reference

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4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity

7 January 2021

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The melanocortin-1 receptor: red hair and beyond

7 January 2021

1 reference

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Binding of cyclic and linear MSH core peptides to the melanocortin receptor subtypes

7 January 2021

1 reference

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Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice

7 January 2021

1 reference

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Phenotypes in three pedigrees with autosomal dominant obesity caused by haploinsufficiency mutations in the melanocortin-4 receptor gene

7 January 2021

1 reference

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Long term orexigenic effect of a novel melanocortin 4 receptor selective antagonist

7 January 2021

1 reference

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EXPERIMENTAL ABLATION OF THE HYPOPHYSIS IN THE FROG EMBRYO

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Proopiomelanocortin processing in the pituitary, central nervous system, and peripheral tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

A metabolic defect promotes obesity in mice lacking melanocortin-4 receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Neural pathways and central sites involved in penile erection: neuroanatomy and clinical implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Receptor biology of the melanocortins, a family of neuroimmunomodulatory peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Molecular interaction of Agouti protein and Agouti-related protein with human melanocortin receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

A frameshift mutation in human MC4R is associated with a dominant form of obesity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Expression of melanocortin receptors and pro-opiomelanocortin in the rat spinal cord in relation to neurotrophic effects of melanocortins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Role of melanocortins in the central control of feeding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Melanocortins and cardiovascular regulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Evidence for two separate opiate peptide neuronal systems

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

The respiratory effects of the cytokine regulating agent HP 228 alone and in combination with morphine in human volunteers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo controlled crossover study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II

7 January 2021

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7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Melanocortin receptors: perspectives for novel drugs

1 reference

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Localization of ACTH receptor mRNA by in situ hybridization in mouse adrenal gland

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Polyclonal antibodies against human melanocortin MC1 receptor: preliminary immunohistochemical localisation of melanocortin MC1 receptor to malignant melanoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Molecular Basis for the Interaction of [Nle4,d-Phe7]Melanocyte Stimulating Hormone with the Human Melanocortin-1 Receptor (Melanocyte α-MSH Receptor)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Characterization of Agouti-related protein binding to melanocortin receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Molecular determinants of ligand binding to the human melanocortin-4 receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

A frameshift mutation in MC4R associated with dominantly inherited human obesity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901425-5

10.1016/S0014-2999(02)01425-5

7 January 2021

Identifiers

DOI

1 reference

3 August 2017

1 reference